ABSTRACT
A 10-year-old child presented after accidental exposure of the left eye to a blue hair dye containing methylene blue. Mild ocular surface changes and a selective blue staining of the usually invisible corneal nerve fibre bundles were present. Corneal sensitivity was reduced. Despite copious lubrication a transient neurotrophic keratitis developed which did not resolve until corneal sensitivity became normal 2 weeks later. Association of mild chemical burns with neurotrophic keratitis is unusual but is of high clinical relevance as keratitis is a vision-threatening complication.
Subject(s)
Burns, Chemical/etiology , Cranial Nerve Diseases/chemically induced , Eye Burns/chemically induced , Keratitis/chemically induced , Methylene Blue/poisoning , Ophthalmic Nerve/drug effects , Burns, Chemical/diagnosis , Burns, Chemical/therapy , Child , Cornea/drug effects , Cornea/innervation , Cranial Nerve Diseases/diagnosis , Cranial Nerve Diseases/therapy , Eye Burns/diagnosis , Eye Burns/therapy , Hair Dyes/chemistry , Hair Dyes/poisoning , Humans , Keratitis/diagnosis , Keratitis/therapy , Male , Treatment OutcomeSubject(s)
Acute Kidney Injury/complications , Acute Kidney Injury/drug therapy , Complementary Therapies/adverse effects , Methylene Blue/poisoning , Shock/chemically induced , Aged , Confusion , Female , Fever , Humans , Hypotension , Methylene Blue/therapeutic use , Shock/physiopathology , Shock/urine , Tachycardia , ThailandABSTRACT
The appearance of a single blob of denatured haemoglobin in red cells staining prominently with supravital dyes is described in a case of fatal haemolysis following infusions of methylene blue (MB) for the treatment of toxic methaemoglobinaemia. This unique inclusion hitherto unreported may be used to predict impending haemolysis.
Subject(s)
Erythrocytes, Abnormal/pathology , Hemolysis/drug effects , Methylene Blue/poisoning , Adolescent , Erythrocytes, Abnormal/drug effects , Fatal Outcome , Humans , Male , Methemoglobinemia/bloodABSTRACT
The authors report two cases of neonatal hemolytic anemia without methemoglobinemia secondary to intraamniotic injection of 10 mg of methylene blue. Evolution was favourable without exchange transfusion. This emphasizes the importance of searching for a toxic origin in case of neonatal hemolytic anemia without apparent cause.
