Military Dictatorship and the Faculty of Medicine-USP: the Experimental Medicine Course, 1967-1982. / Ditadura Militar e a Faculdade de Medicina-USP: o Curso Experimental de Medicina, 1967-1982.

This article aimed to historically assess the impact undergone by the Faculty of Medicine-USP when it formally supported the military regime established in Brazil from 1964 onwards and the consequences of this support in its daily life. Another objective was unearthing how this context, lived between persecution, prisons, and torture, also intervened in didactic-pedagogical actions, such as the creation of a new model of medical education in 1967, known as the Experimental Course. This course would be immediately attacked by groups that saw it as a communist stronghold and a threat to the tradition of the so-called "Casa de Arnaldo", resulting in the closure of its activities in 1974.

O objetivo deste artigo é estudar historicamente o impacto sofrido pela Faculdade de Medicina-USP quando ela apoiou formalmente o regime militar que se estabelecia no Brasil a partir de 1964 e os reflexos desse apoio em seu cotidiano. Outro objetivo é apresentar como esse contexto, vivido entre perseguições, prisões e torturas, interveio também em ações de ordem didático-pedagógica, como na criação de um novo modelo de ensino médico no ano de 1967, conhecido como Curso Experimental. Esse curso seria imediatamente atacado por grupos que o viam como um reduto comunista e uma ameaça à tradição da chamada "Casa de Arnaldo", logrando o encerramento de suas atividades no ano de 1974.

How to Design a (Cybernetic) Revolution: Chileans Remember Salvador Allende's Techno-Utopian Project.

The recent commemoration of the fiftieth anniversary of the military coup led by General Augusto Pinochet offered an opportunity to explore unknown aspects of daily life before and during the dictatorship. This essay focuses on one particular exhibition (How to Design a Revolution: The Chilean Road to Design), which featured a complete reconstruction of the Cybersyn operation room. Based on participant observation, the essay argues that the interaction between visitors and the re-creation in such a particular moment is an invitation to reflect on how technology, socialism, and democracy sought to reinforce each other during the Cold War. The Cybersyn project, one of the most globally recognizable pieces of technology designed in the Global South, still resonates five decades after its implementation (and further destruction by the military), prompting new questions in an era of artificial intelligence and new threats to democracy.

Coronel (SM-M) Doctor Waldemar Vanini Perrone: segundo Director Técnico del Servicio de Sanidad Militar (1974 - 1978) / Colonel (SM-M) Dr. Waldemar Vanini Perrone: second Technical Director of the Military Health Service (1974 - 1978) / Coronel (SM-M) Dr. Waldemar Vanini Perrone: segundo Diretor Técnico do Serviço de Saúde Militar (1974 - 1978)

El 23 de diciembre de 1918 se creó por ley el Servicio de Sanidad del Ejército y la Armada, dependencia del Ministerio respectivo y remoto antecedente de la actual Dirección Nacional de Sanidad de las Fuerzas Armadas de Uruguay. Un Director General con título médico fue designado como jerarca del nuevo Servicio y presidente de su Consejo de Administración. Fue asimilado al grado militar acorde con su jerarquía administrativa: coronel. Mientras la dirección general estuvo a cargo de médicos, éstos fueron designados por ley como Directores Científicos de Sanidad Militar. El Director General Científico tuvo amplísimas atribuciones técnicas y administrativas: reglamentación de los servicios a crearse; representación de la institución; superintendencia técnica de todos los establecimientos; propuesta de nombramientos; asesoramiento del ministerio respectivo; remoción y propuesta de destituciones. El primer Director General de Sanidad fue el médico Francisco Fernández Enciso (1878-1925) quien ejerció el cargo entre 1918 y 1920. Y el último, el médico Guillermo Rodríguez Guerrero, entre 1948 y 1953. Desde entonces, y en forma definitiva, la dirección general quedó a cargo de militares de carrera, pero no médicos, asistidos de un Consejo Técnico Consultivo por médicos del hospital central. El 24 de abril de 1962, se insertó en la Orden del Servicio de Sanidad el nombramiento del coronel médico Hugo Brugnini como Subdirector del Servicio e Inspector General de Servicios de Sanidad. De acuerdo a esta documentación, la Subdirección Técnica del Servicio de Sanidad Militar se inició en 1962 y su primer titular fue el médico Hugo Brugnini. Desde entonces se han nombrado numerosos profesionales para ocupar el cargo de subdirección o lisa y llanamente dirección técnica. Quien sucedió al doctor Brugnini fue el coronel médico Waldemar Vanini, nacido en Montevideo el 16 de febrero de 1924 y fallecido en 1979 en la misma ciudad a la edad de 55 años.

Honores a Sir Ernest Shackleton en Sanidad Militar / Honors to Sir Ernest Shackleton in Military Health / Honras a Sir Ernest Shackleton em Saúde Militar

Ernest Shackleton ha sido en la historia, un personaje que dejó huella como ejemplo de resiliencia y liderazgo. En 1914 realizó como jefe de expedición su segundo viaje antártico, frustrado por el hundimiento de su buque insignia. La operación de rescate del grueso de la tripulación varada en el continente más meridional lo llevó a recalar en Montevideo. Desde este puerto partió el buque Instituto de Pesca N°1, con tripulación de Uruguay y Shackleton incluido, no logrando completar el salvamento. De esta acción nació el aprecio hacia la persona del explorador por parte del gobierno de la República. En su postrer travesía, ya fallecido llegó a las Islas Georgia del Sur y a su cuerpo se le realizó un proceso de conservación para ser traído a nuestro país y continuar viaje al puerto de origen en Inglaterra. Es en esa circunstancia que el gobierno del doctor Baltasar Brum solicitó a la Comisión Permanente del Parlamento, se le rindieran honores fúnebres de Ministro de Estado. El embalsamado del cuerpo fue realizado el 30 de enero de 1922, por parte de personal médico y técnico del Hospital Militar, así como los honores que le rindieron por el Servicio de Sanidad del Ejército y la Armada.

Ernest Shackleton has been in history, a character who left his mark as an example of resilience and leadership. In 1914, as expedition leader, he made his second Antarctic voyage, frustrated by the sinking of his flagship. The operation to rescue the bulk of the crew stranded on the southernmost continent led him to Montevideo. The Instituto de Pesca N°1, with Uruguayan crew and Shackleton included, departed from this port, but was unable to complete the rescue. From this action was born the appreciation of the explorer by the government of the Republic. In his last voyage, when he died, he reached the South Georgia Islands and his body underwent a preservation process to be brought to our country and continue his voyage to the port of origin in England. It is in this circumstance that the government of Dr. Baltasar Brum requested the Permanent Commission of the Parliament to pay him the funeral honors of a Minister of State. The embalming of the body was carried out on January 30, 1922, by medical and technical personnel of the Military Hospital, as well as the honors rendered by the Army and Navy Health Service.

Ernest Shackleton deixou sua marca na história como um exemplo de resiliência e liderança. Em 1914, ele fez sua segunda viagem à Antártica como líder da expedição, frustrado pelo naufrágio de seu navio principal. A operação para resgatar a maior parte da tripulação encalhada no continente mais ao sul o levou a Montevidéu. O Instituto de Pesca N°1, com tripulação do Uruguai e Shackleton incluído, partiu desse porto, mas não conseguiu concluir o resgate. Essa ação deu origem ao reconhecimento do explorador pelo governo da República. Em sua última viagem, quando morreu, chegou às Ilhas Geórgia do Sul e seu corpo foi preservado para que pudesse ser trazido ao nosso país e continuar sua viagem até o porto de origem na Inglaterra. Foi nessa circunstância que o governo do Dr. Baltasar Brum solicitou ao Comitê Permanente do Parlamento que lhe prestasse as honras fúnebres de um Ministro de Estado. O embalsamamento do corpo foi realizado em 30 de janeiro de 1922, pela equipe médica e técnica do Hospital Militar, bem como as honras prestadas a ele pelo Serviço de Saúde do Exército e da Marinha.

Teniente Coronel Médico Profesor Agregado de Cirugía Edgardo Torterolo Prado (1939 ­ 2003), precursor del trasplante hepático en Uruguay / Lieutenant Colonel Medical Attaché Professor of Surgery Edgardo Torterolo Prado (1939 - 2003), precursor of liver transplantation in Uruguay / Tenente Coronel Médico Adido Professor de Cirurgia Edgardo Torterolo Prado (1939 - 2003), precursor do transplante de fígado no Uruguai

Edgardo Gualberto Torterolo Prado, nació en Montevideo el 20 de diciembre de 1939 y falleció en esa ciudad, en la plenitud de su ejercicio profesional, el 31 de julio de 2003. Fueron sus padres Pío Gualberto Torterolo y María Rosaura Prado. Estaba unido en matrimonio con María Elena Minetti (1966) del cual nació su hijo Pablo Daniel un año después. Su vocación lo dirigió hacia la medicina, ingresando a la Facultad oficial en 1959. Luego de su desempeño como practicante interno del Ministerio de Salud Pública (1964-69) obtuvo el título de médico (1968). Se hizo cirujano y en esa especialidad desarrolló dos carreras paralelas: Facultad de Medicina y Servicio de Sanidad Militar.

Edgardo Gualberto Torterolo Prado was born in Montevideo on December 20, 1939 and died in that city, in the fullness of his professional practice, on July 31, 2003. His parents were Pío Gualberto Torterolo and María Rosaura Prado. He was married to María Elena Minetti (1966) and their son Pablo Daniel was born a year later. His vocation directed him towards medicine, entering the official School of Medicine in 1959. After working as an intern at the Ministry of Public Health (1964-69), he obtained his medical degree (1968). He became a surgeon and in that specialty he developed two parallel careers: Medical School and Military Health Service.

Edgardo Gualberto Torterolo Prado nasceu em Montevidéu em 20 de dezembro de 1939 e morreu em Montevidéu, no auge de sua carreira profissional, em 31 de julho de 2003. Seus pais eram Pío Gualberto Torterolo e María Rosaura Prado. Ele foi casado com María Elena Minetti (1966), com quem seu filho Pablo Daniel nasceu um ano mais tarde. Sua vocação o levou à medicina, e ele entrou na Faculdade oficial em 1959. Após trabalhar como estagiário no Ministério da Saúde Pública (1964-69), ele obteve seu diploma de médico (1968). Ele se tornou cirurgião e nessa especialidade desenvolveu duas carreiras paralelas: Faculdade de Medicina e Serviço de Saúde Militar.

Covid-19 y gripe de 1918-1919: paralelos históricos, preguntas y respuestas / Covid-19 and the 1918-1919 influenza: historical parallels, questions and answers

Resumen El desarrollo de la pandemia de la covid-19 ha motivado un renovado interés por la gripe de 1918-1919 para buscar elementos que facilitaran la comprensión de la experiencia presente, pero también como oportunidad para reevaluar la grave crisis sanitaria del siglo XX a la luz de lo que estamos viviendo. En este contexto y con ese objetivo se inserta esta reflexión histórica sobre estos dos fenómenos pandémicos, que muestra los paralelismos existentes y la necesidad de una toma de conciencia de que nuestro modelo de sociedad está en crisis y se requiere una transformación profunda.

Abstract The rise of the covid-19 pandemic has led to renewed interest in the 1918-1919 influenza in search of aspects that might help us understand the current situation, but also as an opportunity to re-evaluate the serious twentieth-century health crisis in light of what we are experiencing now. In this context and with that goal, this historical reflection shows the parallels that exist and the need for a realization that our model of society is undergoing a crisis and requires profound transformation.

Las epidemias en La Pampa (Argentina), en perspectiva histórica* / The epidemics in La Pampa (Argentina), from a historical perspective

Resumen Este artículo describe el inicio de las preocupaciones sanitarias vinculadas a las epidemias ocurridas durante el siglo XX en La Pampa, provincia argentina. Las epidemias, como las de la viruela, fueron un estímulo para estas políticas que frecuentemente tuvieron origen en Buenos Aires, la capital del país. El contagio de muchas epidemias dependía de carencias de infraestructura: agua, desagüe y desecho adecuado de basuras, de la ausencia de un número suficiente de trabajadores de salud, de la presencia de vectores transmisores de enfermedades como los mosquitos y, en última instancia, de la pobreza. La experiencia histórica descrita en este texto resalta la importancia de analizar el impacto del SARS-CoV-2 más allá de las grandes ciudades.

Abstract This article describes the emergence of health concerns relating to the epidemics that occurred during the twentieth century in La Pampa, a province in Argentina. Epidemics such as smallpox drove such policies, which frequently originated in Buenos Aires, the country's capital. The spread of many epidemics was due to shortages: water, sewage and adequate refuse disposal, an insufficient number of health care workers, the presence of disease transmission vectors such as mosquitos, and, ultimately, poverty. The historical experience described in this text highlights the importance of analyzing the impact of SARS-CoV-2 beyond the big cities.

[The epidemics in La Pampa (Argentina), from a historical perspective]. / Las epidemias en La Pampa (Argentina), en perspectiva histórica.

This article describes the emergence of health concerns relating to the epidemics that occurred during the twentieth century in La Pampa, a province in Argentina. Epidemics such as smallpox drove such policies, which frequently originated in Buenos Aires, the country's capital. The spread of many epidemics was due to shortages: water, sewage and adequate refuse disposal, an insufficient number of health care workers, the presence of disease transmission vectors such as mosquitos, and, ultimately, poverty. The historical experience described in this text highlights the importance of analyzing the impact of SARS-CoV-2 beyond the big cities.

Este artículo describe el inicio de las preocupaciones sanitarias vinculadas a las epidemias ocurridas durante el siglo XX en La Pampa, provincia argentina. Las epidemias, como las de la viruela, fueron un estímulo para estas políticas que frecuentemente tuvieron origen en Buenos Aires, la capital del país. El contagio de muchas epidemias dependía de carencias de infraestructura: agua, desagüe y desecho adecuado de basuras, de la ausencia de un número suficiente de trabajadores de salud, de la presencia de vectores transmisores de enfermedades como los mosquitos y, en última instancia, de la pobreza. La experiencia histórica descrita en este texto resalta la importancia de analizar el impacto del SARS-CoV-2 más allá de las grandes ciudades.

[Covid-19 and the 1918-1919 influenza: historical parallels, questions and answers]. / Covid-19 y gripe de 1918-1919: paralelos históricos, preguntas y respuestas.

The rise of the covid-19 pandemic has led to renewed interest in the 1918-1919 influenza in search of aspects that might help us understand the current situation, but also as an opportunity to re-evaluate the serious twentieth-century health crisis in light of what we are experiencing now. In this context and with that goal, this historical reflection shows the parallels that exist and the need for a realization that our model of society is undergoing a crisis and requires profound transformation.

El desarrollo de la pandemia de la covid-19 ha motivado un renovado interés por la gripe de 1918-1919 para buscar elementos que facilitaran la comprensión de la experiencia presente, pero también como oportunidad para reevaluar la grave crisis sanitaria del siglo XX a la luz de lo que estamos viviendo. En este contexto y con ese objetivo se inserta esta reflexión histórica sobre estos dos fenómenos pandémicos, que muestra los paralelismos existentes y la necesidad de una toma de conciencia de que nuestro modelo de sociedad está en crisis y se requiere una transformación profunda.

The 1942 Massive Contamination of Yellow Fever Vaccine: A Public Health Consequence of Scientific Arrogance.

In the late 1930s, the 17D vaccine against yellow fever was produced in record time. 17D was and is an excellent vaccine. Its rapid diffusion led, however, to several problems, the most important among them being the 1942 massive contamination of the vaccine distributed to the US Army by the hepatitis B virus. The US part of this story is relatively well-known, but its Brazilian part much less so. In 1940, scientists who were producing the 17D vaccine in Rio de Janeiro found that it was contaminated by an "icterus virus" that originated in normal human serum. They solved this problem through the exclusion of human serum from vaccine production, but failed to persuade their US colleagues to do the same. The Rio experts, aware of the potential pitfalls of a new technology, carefully supervised the consequences of their vaccination campaigns. They were thus able to rapidly spot problems and eliminate them. By contrast, US scientists, persuaded of their technical superiority and distrustful of warnings that originated from a "less developed" country, neglected to implement basic public health rules. A major disaster followed. (Am J Public Health. 2021;111(9): 1654-1660. https://doi.org/10.2105/AJPH.2021.306313).

Reciprocal Learning Between Military and Civilian Surgeons: Past and Future Paths for Medical Innovation.

Numerous surgical advances have resulted from exchanges between military and civilian surgeons. As part of the U.S. National Library of Medicine Michael E. DeBakey Fellowship in the History of Medicine, we conducted archival research to shed light on the lessons that civilian surgery has learned from the military system and vice-versa. Several historical case studies highlight the need for immersive programs where surgeons from the military and civilian sectors can gain exposure to the techniques, expertise, and institutional knowledge the other domain provides. Our findings demonstrate the benefits and promise of structured programs to promote reciprocal learning between military and civilian surgery.

[From the circumnavigation of the Vital de Oliveira to the new ration tables: nutrition and health on Brazilian Imperial Navy vessels, 1879-1886]. / Da circum-navegação da Vital de Oliveira às novas tabelas de rações: alimentação e saúde a bordo dos navios da Marinha Imperial Brasileira, 1879-1886.

The corvette Vital de Oliveira was the first Brazilian Navy vessel to circumnavigate the world, from 1879 to 1881. One of the items that concerned its captain, Júlio de Noronha, in his trip report was the food supply, which was further reinforced in the medical report for the expedition written by the head surgeon, Galdino Magalhães. This concern was notable due to the high numbers of sailors who sickened and died during the trip, which according to both reports may have been caused by shortages of certain foods. This article discusses the relationship between food and health in the crew, as well as the relationship between this journey and the implementation of a new ration table that took effect in 1886.

Entre 1879 e 1881 a corveta Vital de Oliveira realizou a primeira viagem de circum-navegação da Marinha Brasileira. Um dos itens que ocuparam as preocupações do comandante do navio, Júlio de Noronha, em seu relatório da viagem foi a alimentação; preocupação reforçada no relatório médico da expedição redigido pelo primeiro-cirurgião Galdino Magalhães. Essa preocupação ganhou destaque devido ao elevado saldo de enfermos e mortos durante a viagem, para o que teria contribuído a carência de determinados gêneros alimentícios, de acordo com ambos os relatórios. O artigo discute a relação entre a alimentação e a saúde das tripulações. Além disso, trata da relação entre a viagem da Vital e a implementação de uma nova tabela de rações efetivada em 1886.

Da circum-navegação da Vital de Oliveira às novas tabelas de rações: alimentação e saúde a bordo dos navios da Marinha Imperial Brasileira, 1879-1886 / From the circumnavigation of the Vital de Oliveira to the new ration tables: nutrition and health on Brazilian Imperial Navy vessels, 1879-1886

Resumo Entre 1879 e 1881 a corveta Vital de Oliveira realizou a primeira viagem de circum-navegação da Marinha Brasileira. Um dos itens que ocuparam as preocupações do comandante do navio, Júlio de Noronha, em seu relatório da viagem foi a alimentação; preocupação reforçada no relatório médico da expedição redigido pelo primeiro-cirurgião Galdino Magalhães. Essa preocupação ganhou destaque devido ao elevado saldo de enfermos e mortos durante a viagem, para o que teria contribuído a carência de determinados gêneros alimentícios, de acordo com ambos os relatórios. O artigo discute a relação entre a alimentação e a saúde das tripulações. Além disso, trata da relação entre a viagem da Vital e a implementação de uma nova tabela de rações efetivada em 1886.

Abstract The corvette Vital de Oliveira was the first Brazilian Navy vessel to circumnavigate the world, from 1879 to 1881. One of the items that concerned its captain, Júlio de Noronha, in his trip report was the food supply, which was further reinforced in the medical report for the expedition written by the head surgeon, Galdino Magalhães. This concern was notable due to the high numbers of sailors who sickened and died during the trip, which according to both reports may have been caused by shortages of certain foods. This article discusses the relationship between food and health in the crew, as well as the relationship between this journey and the implementation of a new ration table that took effect in 1886.

Jean Dominique Larrey and his recognition in Mexico.

The figure of Jean Dominique Larrey, military surgeon who participated in the Napoleonic wars, is analyzed. The objectives of the study are to highlight their contributions, including the creation of ambulances that allowed the injured to be given prompt assistance. Also note the post-mortem recognition that Larrey had in Mexico through an academic group founded by the surgeon Francisco Montes de Oca y Saucedo. The facts cited show the progress of military surgery, its institutionalization and professionalization as well as the communication and updating of knowledge in one and another continent.

Se analiza la figura de Jean Dominique Larrey, cirujano militar que participó en las guerras napoleónicas. Los objetivos de estudio consisten en destacar sus aportaciones, entre ellas la creación de las ambulancias que permitieron dar una pronta asistencia al herido. Asimismo, señalar el reconocimiento post mortem que Larrey tuvo en México a través de una agrupación académica fundada por el cirujano Francisco Montes de Oca y Saucedo. Los hechos citados muestran el progreso de la cirugía militar, su institucionalización y profesionalización, así como la comunicación y la actualización de saberes en uno y otro continente.

New anthropometric evidence on living standards in nineteenth-century Chile.

A sample of over 44 thousand Chilean marines was used to estimate the trend of mean heights from the 1820s to the 1890s. We confirm that there was height stagnation in the last decades of the nineteenth-century Chile despite sizeable per capita GDP growth; there were hidden nutritional costs to this economic growth. This situation resembles a similar puzzle in antebellum USA or early industrial Britain, but in the case of Chile GDP growth is not explained by industrialization but by export-led-growth. Still, the results are similar: height stagnation. Regarding the determinants of adult male height, our data also convincingly showed that there was a significant correlation between height and literacy. There was a positive correlation between height and white ethnicity, and, linked to this, a strong negative correlation between stature and eyes reported as "black". Finally, living in urban environments (or environments with higher population density) also negatively affected height.

[The military health service in the process of modernization, bureaucratization and professionalization of the Argentine Army (1888-1938)]. / El servicio de sanidad militar en el proceso de modernización, burocratización y profesionalización del ejército argentino (1888-1938).

At the end of the 19th and beginning of the 20th century, a process of modernization, bureaucratization and professionalization of the Argentine Army was initiated. As a result of this process, Army divisions were formed, which are autonomous military organizations composed of units of various weapons, combat support elements and services. Included among the latter was the military health service, which acted both in the operational units of the military districts in order to incorporate citizens into the Compulsory Military Service as well as in military hospitals. This article aims to: 1) characterize this process in relation to the concepts of defense, organization, functions and territorial deployment of the Army; 2) analyze, within that framework, the formation of the military health service between 1888 -when the Organic Law of the Sanitary Corp of the Army and the Navy was sanctioned - and 1938 - when the Army's organic design was changed on the eve of the Second World War.

Hacia fines del siglo XIX y principios del siglo XX se inició la modernización, burocratización y profesionalización del Ejército Argentino. Como resultado de ese proceso se conformaron las divisiones del Ejército, esto es, organizaciones militares autónomas entre sí, compuestas por unidades de diferentes armas, elementos de apoyo de combate y de servicios. Entre estos últimos estaba el de sanidad militar, que actuaba en las unidades operativas de los distritos militares para el reconocimiento de los ciudadanos para el Servicio Militar Obligatorio y en los hospitales militares. Este artículo tiene por objetivos: 1) caracterizar ese proceso en sus relaciones con las concepciones de la defensa, organización, funciones y despliegue territorial del Ejército; 2) analizar, en ese marco, la conformación del servicio de sanidad militar entre 1888, con la sanción de la Ley Orgánica del Cuerpo de Sanidad del Ejército y la Armada, y 1938, con los cambios en el diseño orgánico del Ejército en vísperas de la Segunda Guerra Mundial.

[Between vaccines, diseases, and resistances: the impacts of a smallpox epidemic in nineteenth-century Porto Alegre]. / Entre vacinas, doenças e resistências: os impactos de uma epidemia de varíola em Porto Alegre no século XIX.

This article examines a smallpox epidemic which killed 1% of the population of Porto Alegre in 1874. Through extensive documentary research and comparison with data from those who died, we problematize why smallpox manifested as an epidemic in the city. Maps showing vaccination in the years preceding the outbreak reveal that only low levels of the population of Porto Alegre participated in prevention efforts, and the benefits of these efforts were ignored by the different social groups which were interconnected within the city. As sick soldiers arrived from other places, the disease spread rapidly through the city and caused the death of hundreds of people.

Uma epidemia de varíola que vitimou fatalmente 1% da população de Porto Alegre em 1874 é o tema deste artigo. Com base em ampla pesquisa documental e no cruzamento de informações produzidas por ocasião da morte dos indivíduos atingidos durante o evento, buscamos problematizar as razões pelas quais a varíola apresentou-se em formato epidêmico na cidade. De posse dos mapas de vacinados nos anos anteriores à eclosão da epidemia, pudemos constatar a baixa adesão da população de Porto Alegre ao preventivo, cujo benefício poderia ser ignorado pelos distintos grupos sociais que teciam relações dentro da cidade. Com a chegada de soldados doentes, oriundos de outras localidades, a moléstia se espalhou rapidamente pela cidade, causando a morte de centenas de pessoas.

Entre vacinas, doenças e resistências: os impactos de uma epidemia de varíola em Porto Alegre no século XIX / Between vaccines, diseases, and resistances: the impacts of a smallpox epidemic in nineteenth-century Porto Alegre

Resumo Uma epidemia de varíola que vitimou fatalmente 1% da população de Porto Alegre em 1874 é o tema deste artigo. Com base em ampla pesquisa documental e no cruzamento de informações produzidas por ocasião da morte dos indivíduos atingidos durante o evento, buscamos problematizar as razões pelas quais a varíola apresentou-se em formato epidêmico na cidade. De posse dos mapas de vacinados nos anos anteriores à eclosão da epidemia, pudemos constatar a baixa adesão da população de Porto Alegre ao preventivo, cujo benefício poderia ser ignorado pelos distintos grupos sociais que teciam relações dentro da cidade. Com a chegada de soldados doentes, oriundos de outras localidades, a moléstia se espalhou rapidamente pela cidade, causando a morte de centenas de pessoas.

Abstract This article examines a smallpox epidemic which killed 1% of the population of Porto Alegre in 1874. Through extensive documentary research and comparison with data from those who died, we problematize why smallpox manifested as an epidemic in the city. Maps showing vaccination in the years preceding the outbreak reveal that only low levels of the population of Porto Alegre participated in prevention efforts, and the benefits of these efforts were ignored by the different social groups which were interconnected within the city. As sick soldiers arrived from other places, the disease spread rapidly through the city and caused the death of hundreds of people.

Walter Reed at Camp Lazear: A Paradigm for Contemporary Clinical Research.

Throughout the time of the early settlement and development of North America, there were frequent epidemics of Yellow Fever. It is thought that ships transporting captured Africans likely conveyed both major vectors, the Aedes aegypti mosquito and the RNA Yellow Fever virus from Africa to North America. Infected ships landing in port cities resulted in epidemics that proved impossible to control with conventional interventions. Walter Reed and the U.S. Army Commission solved the mystery of the mode of Yellow Fever transmission. Reed and his co-workers not only proved the mosquito the vector of transmission but did so by constructing focused research questions leading to cleverly devised experiments that resulted in definitive answers. The results of their research not only proved that the mosquito transmitted the disease but disproved the other proposed modes of transmission. In nearly all respects, Reed's experiments are an excellent paradigm for addressing clinical research questions today.