ABSTRACT
La hipercalcemia secundaria a enfermedad neoplásicaes una entidad frecuente causada en la mayor partede los casos por secreción ectópica de PTHrp. A pesarde esto hay ciertos tumores, como los carcinomas uterinos,en donde este tipo de manifestación paraneoplásicaestá muy poco descrita. Presentamos un caso dehipercalcemia humoral en un carcinoma mixto de endometrio (AU)
Hypercalcemia secondary to neoplastic diseaseis a frequent entity caused in the majority of cases byectopic secretions of PTHrP. Despite this there are certaintumours, such as uterine carcinomas, in which thistype of paraneoplastic manifestation has been describedvery little. We present a case of humoral hypercalcemiain a mixed endometrial carcinoma (AU)
Subject(s)
Humans , Female , Aged, 80 and over , Hypercalcemia/complications , Hypercalcemia/diagnosis , Mixed Tumor, Mesodermal/complications , Mixed Tumor, Mesodermal/diagnosis , Mixed Tumor, Malignant/complications , Paraneoplastic Endocrine Syndromes/complications , Paraneoplastic Endocrine Syndromes/diagnosis , Hysterectomy/methods , Cell Dedifferentiation/physiology , Hypercalcemia/surgery , Hypercalcemia , Mixed Tumor, Mesodermal , Cervix Uteri/pathology , Cervix Uteri , Uterine Neoplasms/complications , Uterine Neoplasms , Paraneoplastic Syndromes/complications , Lymph Node ExcisionABSTRACT
A rare case of uterine's mixed mesodermal malignant tumor in young woman was described. Clinical symptoms, risk groups, treatment, and prognosis were presented. It was noticed that every year younger women are attacked by this kind of tumor.
Subject(s)
Mixed Tumor, Mesodermal , Uterine Neoplasms , Adult , Fatal Outcome , Female , Humans , Mixed Tumor, Mesodermal/complications , Mixed Tumor, Mesodermal/diagnosis , Mixed Tumor, Mesodermal/therapy , Time Factors , Uterine Hemorrhage/etiology , Uterine Neoplasms/complications , Uterine Neoplasms/diagnosis , Uterine Neoplasms/therapyABSTRACT
BACKGROUND: Malignant mixed mesodermal tumors (MMMTs) are uncommon, highly aggressive tumors of the uterus composed of both carcinomatous and sarcomatous elements, both likely to be derived from the same original stem cell. There is a strong association between endometrial adenocarcinoma and polycystic ovary disease. However, only two cases of MMMT occurring in women with polycystic ovaries have been reported. CASE: A 36-year-old woman with polycystic ovary disease developed an MMMT of the endometrium. CONCLUSION: Some cases of MMMT may be estrogen related.
Subject(s)
Mixed Tumor, Mesodermal/diagnosis , Polycystic Ovary Syndrome/diagnosis , Uterine Neoplasms/diagnosis , Adult , Anemia/etiology , Diagnosis, Differential , Female , Humans , Mixed Tumor, Mesodermal/complications , Mixed Tumor, Mesodermal/pathology , Mixed Tumor, Mesodermal/radiotherapy , Mixed Tumor, Mesodermal/surgery , Polycystic Ovary Syndrome/complications , Polycystic Ovary Syndrome/pathology , Polycystic Ovary Syndrome/radiotherapy , Polycystic Ovary Syndrome/surgery , Uterine Hemorrhage/etiology , Uterine Neoplasms/complications , Uterine Neoplasms/pathology , Uterine Neoplasms/radiotherapy , Uterine Neoplasms/surgeryABSTRACT
The authors report an unusual case of post-menopausal bleeding in the form of a benign mixed tumour of the vagina.
Subject(s)
Mixed Tumor, Mesodermal/complications , Uterine Hemorrhage/etiology , Uterine Neoplasms/complications , Vaginal Neoplasms/complications , Aged , Aged, 80 and over , Female , Humans , Mixed Tumor, Mesodermal/pathology , Postmenopause , Uterine Neoplasms/pathology , Vaginal Neoplasms/pathologyABSTRACT
Ovarian carcinoma commonly has an insidious onset. By the time the diagnosis is made, advanced disease is usually present. Rarely does a patient have acute symptoms which require immediate medical attention and lead to the correct diagnosis. A 40-year-old white female presented with lower abdominal pain, nausea, and light-headedness. Physical examination revealed a markedly tender lower abdomen with the right lower quadrant slightly more tender than the left. Hemoglobin level was noted to have decreased 2.6 g/dl over 16 hr. At exploratory laparotomy, 1500 cc of blood and a ruptured right ovarian mass were found. Pathologic analysis revealed a malignant mixed mesodermal tumor of the right ovary and an endometrioma of the left ovary. In conclusion, ovarian carcinoma may present as an acute abdomen because of intra-abdominal hemorrhage. It should be part of the differential diagnosis in a woman with an acute surgical abdomen and a hemoperitoneum.
