Subject(s)
Mucinoses/congenital , Skin/pathology , Biopsy , Child , Child, Preschool , Female , Follow-Up Studies , Humans , Infant , Infant, Newborn , Mucinoses/diagnosis , Mucinoses/pathologyABSTRACT
Cutaneous mucinosis in infancy is rare. We report an infant with multiple congenital papules distributed over the trunk, neck, and extremities. These papules were mainly dispersed, but they also coalesced into plaques. Histopathologic findings showed features of cutaneous mucinosis of infancy (CMI). Over 2 years of follow-up, we observed that the preexisting lesions on the lower back and left trunk progressively increased in size, and a few new scattered papules continued to appear, mainly on the trunk; several lesions spontaneously resolved with no further complications. CMI is considered to be a persistent cutaneous disorder, even though spontaneously regressing cases have rarely been reported. This case demonstrates the broad clinical spectrum of CMI, with progressive, eruptive, and spontaneously involuting lesions all present in the same patient. This condition should be considered in the differential diagnosis of congenital or infantile-onset papules and plaques, especially those yellowish in color.
Subject(s)
Mucinoses/diagnosis , Skin Diseases/diagnosis , Diagnosis, Differential , Female , Humans , Infant , Mucinoses/congenital , Skin/pathology , Skin Diseases/congenitalABSTRACT
The nomenclature and classification of cutaneous mucinosis is quite complex. An updated classification of idiopathic cutaneous mucinosis (lichen myxoedematosus), included three clinicopathological subsets: a generalized papular and sclerodermoid form, a localized papular form, and an atypical or intermediate form. Cutaneous mucinosis occurring in infancy is very rare. We report a 7-month-old boy with a history of multiple opalescent papules over his fingers and toes since birth. The lesions spontaneously regressed and became indiscernible after 5 years of clinical follow-up. The condition was similar to cutaneous mucinosis of infancy but was also unique because of its spontaneous regression and acral location.
Subject(s)
Mucinoses/congenital , Skin Diseases/congenital , Fingers/pathology , Follow-Up Studies , Humans , Infant , Male , Mucinoses/pathology , Remission, Spontaneous , Skin Diseases/pathology , Toes/pathologyABSTRACT
Mucinous nevus is a very rare entity and can be classified as both a cutaneous mucinosis (CM) and a connective tissue nevus (CTN). We describe the clinicopathologic features of an unusual case of mucinous nevus in a 14-year-old Korean boy who presented with zosteriform plaques of congenital onset.
Subject(s)
Nevus, Pigmented/pathology , Proteoglycans/analysis , Skin Abnormalities/pathology , Soft Tissue Neoplasms/pathology , Adolescent , Biopsy, Needle , Connective Tissue/pathology , Follow-Up Studies , Humans , Immunohistochemistry , Korea , Male , Mucinoses/congenital , Mucinoses/pathology , Nevus, Pigmented/congenital , Rare Diseases , Soft Tissue Neoplasms/congenitalABSTRACT
A case of childhood cutaneous mucinosis is described. This is a clinical condition that is rarely seen and has only recently been included in the group of primary mucinosis.
