[Fetal inflammatory response in the development of multiple organ dysfunction in newborn].

The fetal inflammatory response syndrome (FIRS) is one of the causes of multiple organ dysfunction (MOD) in critically ill newborn infants. The paper shows a role of interleukin-8 (IL-8) in the development of FIRS and MOD in neonates a correlation between the concentration of IL-8 and the number of organs involved in the pathological process and demonstrates the leading role of endothelial dysfunction in the pathogenesis of the pathological processes concerned.