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1.
J Laryngol Otol ; 136(4): 333-340, 2022 Apr.
Article in English | MEDLINE | ID: mdl-35000626

ABSTRACT

OBJECTIVES: To determine whether: the N95 respirator affects nasal valve patency; placement on the bony vault improves patency; and external nasal anatomy affects the outcome. METHODS: A prospective study with 50 participants was conducted. Nasal patency was measured by the minimal cross-sectional area via acoustic rhinometry, and using the Nasal Obstruction Symptom Evaluation survey, before and after wearing the N95 respirator and after adjustment. RESULTS: The minimal cross-sectional area was narrowed by 27 per cent when wearing the N95 respirator (p < 0.001), and improved by 9.2 per cent after adjustment (p = 0.003). The total Nasal Obstruction Symptom Evaluation score increased from 10.2 to 25.4 after donning the N95 respirator (p < 0.001), and decreased from 25.4 to 15.6 after adjustment (p < 0.001). There was no correlation with external nasal anatomy parameters. CONCLUSION: Wearing the N95 respirator causes narrowing of the nasal valve, and adjustment onto the bony vault improves symptoms. The findings were not affected by external nasal anatomy.


Subject(s)
Nasal Obstruction , Respiratory Protective Devices , Cohort Studies , Humans , N95 Respirators , Nasal Obstruction/etiology , Nasal Obstruction/prevention & control , Prospective Studies
2.
Facial Plast Surg Aesthet Med ; 23(3): 172-179, 2021.
Article in English | MEDLINE | ID: mdl-32716730

ABSTRACT

Background: Septal extension grafts (SEGs) are used widely in rhinoplasty as a means of controlling tip position. Grafts positioned in a side-to-side configuration may cause nasal airway obstruction. Methods: Retrospective cohort analysis of patients undergoing cosmetic rhinoplasty. Patients undergoing SEG placement were grouped according to completion of the Nasal Obstruction Symptom Evaluation (NOSE) or Standardized Cosmesis and Health Nasal Outcomes Survey (SCHNOS). The latter has a cosmetic (C) and functional (O) domain. Each group was matched to a cohort that did not undergo SEG placement using criteria: preoperative NOSE or SCHNOS-O score, age, and gender. Patient demographics and outcomes, including NOSE, SCHNOS, and visual analog scale (VAS) scores, were compared between SEG and no-SEG groups using univariate and multivariate analyses. If patients underwent placement of an SEG and complained of obstruction, the laterality of the graft in relation to the complaint was examined. Results: SEGs were placed in 79 patients, of whom 77 completed the NOSE survey and 37 completed the SCHNOS-O both pre- and postoperatively. These patients were matched to patients without SEGs. For both the SCHNOS and NOSE-matched cohorts, functional outcomes (NOSE, SCHNOS-O, and VAS-F) did not significantly differ between SEG and no-SEG groups. These findings were also observed when patients were stratified by cosmetic surgery alone versus combined functional and cosmetic surgery. On multivariate linear regression analysis, when accounting for intraoperative techniques, there was no difference in postoperative NOSE or SCHNOS-O outcomes between the SEG and no-SEG cohorts. Side of postoperative nasal obstruction did not correlate with side of SEG placement. Conclusion: SEGs, when used in a unilateral side-to-side configuration, yield excellent aesthetic results without compromising functional outcomes.


Subject(s)
Nasal Obstruction/etiology , Nasal Septum/transplantation , Postoperative Complications/etiology , Rhinoplasty/methods , Adolescent , Adult , Esthetics , Female , Follow-Up Studies , Humans , Linear Models , Male , Matched-Pair Analysis , Middle Aged , Multivariate Analysis , Nasal Obstruction/diagnosis , Nasal Obstruction/epidemiology , Nasal Obstruction/prevention & control , Patient Reported Outcome Measures , Postoperative Complications/diagnosis , Postoperative Complications/epidemiology , Postoperative Complications/prevention & control , Retrospective Studies , Young Adult
3.
Sleep Breath ; 25(2): 1019-1027, 2021 Jun.
Article in English | MEDLINE | ID: mdl-32648185

ABSTRACT

OBJECTIVE: The aim of this study is to evaluate the impact of rapid palatal expansion (RPE) on the nasal airway subjectively by utilizing patient-reported outcome measures (PROM) and objectively by evaluating validated internal nasal valve (INV) measurements obtained from cone beam computed tomography (CBCT) in pediatrics. MATERIALS AND METHODS: In this retrospective cohort study, subjects who underwent RPE from March to December 2018 with cone beam CT and Nasal Obstruction Symptom Evaluation (NOSE) scores were included. Exclusion criteria included craniofacial deformity, allergies, asthma, recent nasal trauma, or surgery. INV measurements (angle and cross-sectional area), diastema, midpalatal suture opening, and NOSE scores were evaluated. RESULTS: Fifty-one subjects met the inclusion criteria with a mean age of 10.1 ± 2.6. Pre-expansion mean NOSE score was 32.55 (moderate) while post-expansion was 13.92 (mild). Mean NOSE score improved significantly by an average of 18.63 following post-expansion (P < 0.0001). The patients' right and left INV angles increased significantly by a mean of 2.42° and 2.65° respectively (P < 0.0001). Right and left INV cross-sectional areas increased significantly by an average of 14.35 mm2 (P < 0.0001) and 14.17 mm2 (P < 0.0001) respectively. An average expansion of the diastema and the suture was 1.60 mm and 3.05 mm respectively (P < 0.0001), with an average of 6.29 mm of expansion. We found the amount of diastema expansion to correlate with change in NOSE score (R = - 0.32, P = 0.022). Age and diastema showed a negative correlation (R = - 0.44, P = 0.0019), while INV angle and diastema showed a statistically significant positive correlation (R = 0.28, P = 0.048). CONCLUSIONS: RPE showed improvement in both NOSE scores and objective measures of the INV. This may show the possibility of considering RPE in managing resistant pediatric nasal airways. Future studies should include collaboration with pediatric otolaryngologists, with the inclusion of pediatric patients with persistent nasal obstruction.


Subject(s)
Nasal Cavity/physiology , Nasal Obstruction/prevention & control , Palatal Expansion Technique , Child , Cone-Beam Computed Tomography , Female , Humans , Male , Nasal Cavity/diagnostic imaging , Nasal Obstruction/diagnostic imaging , Retrospective Studies , Treatment Outcome
4.
Am J Otolaryngol ; 41(6): 102641, 2020.
Article in English | MEDLINE | ID: mdl-32682612

ABSTRACT

BACKGROUND: Common warts rarely occur on the nasal vestibule. It should be treated more carefully than other skin lesions because scar contracture results in the narrowing of the external naris, causing nasal obstruction and reducing the patient's quality of life. In this report, we introduce our method for common warts on the nasal vestibule using handheld cryoablation devise. PATIENTS AND OPERATIVE METHODS: We performed a series of four cryosurgical ablation procedures to treat common warts on the nasal vestibule. All the procedures employed a reusable handheld cryoablation device (CRY-AC®, Brymill Cryogenic Systems, Ellington, CT). RESULT: All patients were successfully treated for four to six sessions without any adverse event. CONCLUSION: Cryotherapy for common warts on nasal vestibular is easily performed in an office setting under no anesthesia without bleeding. We believe this easy and safe procedure is suitable as the first line therapy for common wart on nasal vestibular.


Subject(s)
Cryosurgery/instrumentation , Cryosurgery/methods , Nasal Cavity/surgery , Nose Diseases/surgery , Warts/surgery , Adolescent , Adult , Cryosurgery/adverse effects , Female , Humans , Male , Middle Aged , Nasal Obstruction/etiology , Nasal Obstruction/prevention & control , Postoperative Complications/etiology , Postoperative Complications/prevention & control , Safety , Treatment Outcome
5.
J Laryngol Otol ; 134(3): 270-271, 2020 Mar.
Article in English | MEDLINE | ID: mdl-32122421

ABSTRACT

BACKGROUND: Endoscopic frontal sinus surgery is frequently complicated by post-operative stenosis and obstruction of the frontal sinus outflow tract, resulting in recurrent disease. Frontal sinus stents may help prevent re-occlusion of the frontal neo-ostia. OBJECTIVE: This paper presents a simple and cost-effective approach to frontal sinus stenting using modified Silastic nasal splints. RESULTS AND CONCLUSION: The current technique provides an effective, reliable and inexpensive method for achieving post-operative frontal sinus outflow tract patency.


Subject(s)
Endoscopy/instrumentation , Frontal Sinus/surgery , Nasal Surgical Procedures/instrumentation , Paranasal Sinus Diseases/surgery , Stents , Constriction, Pathologic/etiology , Constriction, Pathologic/prevention & control , Endoscopy/methods , Frontal Sinus/pathology , Humans , Nasal Obstruction/etiology , Nasal Obstruction/prevention & control , Nasal Surgical Procedures/methods , Postoperative Complications/etiology , Postoperative Complications/prevention & control , Recurrence , Treatment Outcome
6.
Ann Plast Surg ; 83(4): 381-383, 2019 10.
Article in English | MEDLINE | ID: mdl-31524727

ABSTRACT

BACKGROUND: Rhinoplasty is a one of the most commonly performed facial surgery aiming at restoring facial aesthetics and improving quality of life. Utility outcome scores are modern, and emerging tools are used to evaluate the burden of a health state on individuals. The study aims to evaluate the impact of living with nasal deformity among real patients and healthy individuals using utility outcome scores. METHODS: A cross-sectional study was conducted at Otolaryngology and Plastic Surgery clinics in a tertiary center. Healthy individuals were recruited from public facilities. A case scenario was developed to reflect an imaginary patient (Nora) with a functional and aesthetic nasal deformity and distributed to participants. Three utility outcomes scores were used: visual analog scale (VAS), time trade-off (TTO), and standard gambling (SG). RESULTS: A total of 407 adult participants were included. Most participants were female (52%). Healthy individuals comprised 71%, and actual patients comprised 29%. Mean VAS score was 0.77 (ie, participants scored Nora's health state as 77%), TTO score was 0.87 (ie, participants were willing to sacrifice 4 years to have Nora's condition corrected), and SD score was 0.91 (ie, participants were willing to take a 9% risk of death to have Nora's condition corrected). Scores differed among actual patients and healthy individuals (P < 0.0001 for VAS and TTO, P = 0.02 for SG). CONCLUSION: Living with a nasal deformity has a significant impact on quality of life. Both patients and healthy individuals are willing to trade a significant number of years to get the condition corrected.


Subject(s)
Cost of Illness , Nasal Obstruction/prevention & control , Nose/abnormalities , Quality of Life , Rhinoplasty/methods , Adult , Congenital Abnormalities/diagnosis , Congenital Abnormalities/surgery , Cross-Sectional Studies , Developing Countries , Female , Humans , Male , Middle Aged , Nose/surgery , Retrospective Studies , Rhinoplasty/economics , Saudi Arabia , Tertiary Care Centers , Visual Analog Scale , Young Adult
7.
Eur Arch Otorhinolaryngol ; 276(8): 2251-2257, 2019 Aug.
Article in English | MEDLINE | ID: mdl-31076882

ABSTRACT

PURPOSE: Nasal packing is frequently used after septoplasty and some complications caused by nasal packing are unavoidable. A nasal septal retainer has recently been developed. We evaluated the safety and clinical efficacy of the retainer in septoplasty, and the subjective symptoms of patients with the retainer were compared with Merocel nasal packing. METHODS: A prospective, randomized, controlled study was performed in patients who had undergone septoplasty. In total, 39 patients were randomized to receive Merocel (n = 17) or the retainer (n = 22) after septoplasty. The deviation of nasal septum and nasal mucosa was evaluated by endoscopy. The clinical efficacy and subjective symptoms were compared using the visual analog scale. RESULTS: During the packing/retaining period, the mean scores of headache, nasal obstruction, epiphora, and facial pressure in the retainer group were significantly lower than in the Merocel group (P < 0.05); the mean scores of nasal pain, nasal itching, rhinorrhea, dysphagia, and sleep disturbance in the retainer group were lower than in the Merocel group, but the difference did not reach statistical significance. On the removal of Merocel/retainer, nasal pain was significantly lower in patients with the retainer (P < 0.05). In the retainer group, the incidence of grade 1 bleeding was 45.5%, and grade 0 bleeding was 54.5%. In the Merocel group, the incidence of grade 2 bleeding was 23.5%, grade 1 was 47.1%, and grade 0 was 29.4%. CONCLUSIONS: The nasal septal retainer is suitable for use after septoplasty with more beneficial effects than nasal packing.


Subject(s)
Formaldehyde/therapeutic use , Nasal Obstruction , Nasal Septum/surgery , Nasal Surgical Procedures , Polyvinyl Alcohol/therapeutic use , Postoperative Hemorrhage , Adult , Endoscopy/methods , Female , Hemostatics/therapeutic use , Humans , Male , Nasal Cavity/diagnostic imaging , Nasal Obstruction/diagnosis , Nasal Obstruction/etiology , Nasal Obstruction/prevention & control , Nasal Surgical Procedures/adverse effects , Nasal Surgical Procedures/methods , Occlusive Dressings/adverse effects , Postoperative Hemorrhage/diagnosis , Postoperative Hemorrhage/prevention & control , Treatment Outcome
8.
Clin Respir J ; 13(6): 384-390, 2019 Jun.
Article in English | MEDLINE | ID: mdl-30938064

ABSTRACT

OBJECTIVES: Adherence to continuous positive airway pressure (CPAP) remains an issue, as adverse effects (AE) such as rhinitis, dry/congested nose, dry mouth or throat are commonly experienced. The aim of the study was to compare CPAP efficacy and tolerance in severe obstructive sleep apnea (OSA) patients with or without (w/o) heated humidification using the ThermoSmart system. METHODS: Multicenter RCT study in which CPAP-naive patients with severe OSA and meeting one or more of the following criteria: >65 years, using >1 drying medication, previous nasal symptoms or nasal surgery, were included. Patients were randomized to CPAP w/o heated humidification for 1 month and then crossed-over to the other treatment arm for another month. Naso-pharyngeal symptoms, Quality of life (FOSQ-10), sleepiness (ESS) and CPAP compliance and efficacy data were collected. RESULTS: Forty patients were enrolled: age 62 ± 9 years, diagnostic AHI 46.7 ± 15.3/hour. About 70% were using >1 drying medication, mainly antihypertensives. Both treatment modalities were found to normalize AHI and decrease sleepiness with no differences between 2 modes, compliance (4.63 ± 0.39 vs 4.70 ± 0.36 h/night) or leaks (32.4 ± 2.0 versus 31.1 ± 1.7l/min). With heated humidification, there was a significant decrease in nasal symptoms such as dry/congested nose. At the study end, 26 patients preferred ThermoSmart ON, 3 did not have preference and 11 preferred ThermoSmart OFF. CONCLUSION: ThermoSmart helps to decrease nose and throat discomfort because of CPAP therapy, these effects did not translate to better compliance but patients had a preference for ThermoSmart.


Subject(s)
Continuous Positive Airway Pressure/adverse effects , Nasal Obstruction/prevention & control , Sleep Apnea, Obstructive/therapy , Aged , Continuous Positive Airway Pressure/methods , Cross-Over Studies , Double-Blind Method , Female , France , Hot Temperature , Humans , Humidifiers , Male , Nasal Obstruction/etiology , Patient Compliance , Quality of Life , Treatment Outcome
9.
Eur Arch Otorhinolaryngol ; 276(5): 1397-1403, 2019 May.
Article in English | MEDLINE | ID: mdl-30788581

ABSTRACT

PURPOSE: Budesonide improves the prognosis of chronic rhinosinusitis (CRS). However, few reports have examined whether its use for nasal irrigation, compared to normal saline, improves the prognosis of patients after endoscopic sinus surgery (ESS). We compared the effects of nasal irrigation with budesonide and normal saline in CRS patients after ESS. METHODS: Sixty CRS patients who had undergone ESS were randomly divided into an experimental group (30 patients), which used budesonide nasal irrigation, and a control group (30 patients), which used normal saline nasal irrigation. All patients received regular follow-up evaluations and were assessed via questionnaires, including the Lund-Kennedy endoscopic score (LKES), the symptom visual analog scale (VAS), the 22-item Sino-Nasal Outcome Test (SNOT-22), the Short-Form 36-Item Questionnaire (SF-36), the Self-Rating Anxiety Scale (SAS), the Self-Rating Depression Scale (SDS) and a side effects scale. RESULTS: Scores of polyposis, mucosal edema, secretions and total score of LKES; VAS scores of nasal blockage, hyposmia and rhinorrhea; and SNOT-22 results in both groups were significantly improved 3 months after ESS. Scores of polyposis, mucosal edema, secretions and scarring and total score of LKES in experimental group were significantly better than in control group 3 months after ESS. No significant differences were observed in SF-36, SAS or SDS before or 3 months after ESS within or between the two groups. The side effects of the two groups were not significantly different. CONCLUSIONS: Nasal irrigation improved the prognosis of CRS patients after ESS. Budesonide nasal irrigation had a better effect than normal saline nasal irrigation.


Subject(s)
Budesonide/administration & dosage , Endoscopy , Nasal Lavage/methods , Nasal Obstruction , Paranasal Sinuses , Rhinitis , Sinusitis , Adult , Anti-Inflammatory Agents/administration & dosage , Chronic Disease , Endoscopy/adverse effects , Endoscopy/methods , Female , Humans , Male , Middle Aged , Nasal Obstruction/diagnosis , Nasal Obstruction/etiology , Nasal Obstruction/prevention & control , Paranasal Sinuses/diagnostic imaging , Paranasal Sinuses/drug effects , Paranasal Sinuses/surgery , Postoperative Complications/diagnosis , Postoperative Complications/prevention & control , Prognosis , Rhinitis/diagnosis , Rhinitis/surgery , Sinusitis/diagnosis , Sinusitis/surgery , Treatment Outcome
10.
JAMA Facial Plast Surg ; 21(1): 38-43, 2019 Jan 01.
Article in English | MEDLINE | ID: mdl-30193353

ABSTRACT

IMPORTANCE: Postoperative packing in nasal surgery often results in nasal obstruction and discomfort. Commercially available silicone intranasal airways (IAs) serve as dual-nasal airway tubes aimed at alleviating this process, but the safety and efficacy of these devices are unknown. OBJECTIVE: To evaluate the safety and efficacy of an intraoperatively placed IA device in rhinoplasty and nasal surgery. DESIGN, SETTING, AND PARTICIPANTS: In this retrospective record review, the medical records of patients undergoing nasal surgery with insertion of the IA at a single institution from 2012 to 2017 were reviewed. After review of over 200 patients, a questionnaire was developed to assess device efficacy. EXPOSURES: Use of the IA device. The IA is 12 cm long, anchored across the columella, extends distally along the nasal floor, and has a proximal external portion used for cleaning and maintaining patency. Placed intraoperatively, the device aims to support air flow postoperatively in the face of edema, hemorrhage, and packing. RESULTS: A total of 302 operations in 300 patients were analyzed, including primary and revision septorhinoplasty. A total of 24 (7.9%) patients self-removed or inadvertently dislodged the IA. Minor acute postoperative complications not unique to airway insertion included cellulitis in 4 (1.3%) participants and epistaxis in 6 (2%). Postoperatively, 1 (0.3%) patient developed dehiscence along transcolumellar incisions. A total of 59 patients (100% compliance) completed the efficacy questionnaire. The mean breathing score was between good and average (2.9 of 5), comfort scores between comfortable and average (2.9 of 5), and mean ease of irrigation score was between very easy and easy (1.96 of 5). The device was irrigated on average 3.57 times per day. A total of 43 (76%) particpiants had full patency or only partial obstruction, compared with 13 (24%) patients with total obstruction. In all patients, with or without obstruction, the effect lasted an average of 4 days. CONCLUSIONS AND RELEVANCE: The device is safe and well-tolerated for maintaining patency of the nasal airway in patients undergoing rhinoplasty and nasal reconstruction without increased risk of incisional dehiscence. LEVEL OF EVIDENCE: 4.


Subject(s)
Nasal Obstruction/prevention & control , Nose Diseases/surgery , Postoperative Complications/prevention & control , Prostheses and Implants , Equipment Safety , Female , Humans , Male , Prosthesis Design , Retrospective Studies , Rhinoplasty , Surveys and Questionnaires
12.
Aesthetic Plast Surg ; 43(1): 175-183, 2019 02.
Article in English | MEDLINE | ID: mdl-30019240

ABSTRACT

INTRODUCTION: The position of the lower lateral cartilages (LLC) is closely related to the function of the external nasal valve (ENV). When there is a cephalic malposition of these cartilages, the nasal alae have inadequate support, which leads to ENV insufficiency during deep inspiration. METHODS: Retrospective study with 60 patients evaluated: the positioning of the LLC and the occurrence of ENV insufficiency; the effectiveness of structuring the medial and lateral walls of the ENV; and the frequency of the grafts used for structuring it. RESULTS: Of the 60 operated cases, 37 patients (62%) had ENV insufficiency, in 23 cases there was cephalic malposition of the LLC, and in the latter group 17 patients (74%) presented this insufficiency. A structured ENV was effective in the treatment of this insufficiency (p = 0.001). A lateral crural strut graft was performed in 24 cases (40%) of 60 patients operated. The alar contour graft was performed from 2013 to 2015 in 4 patients (22%) of 18 cases operated, and between 2016 and 2018 it was performed in 29 patients (69%) out of 42 cases. The columellar strut was routinely used from 2013 to mid-2016 in 33 cases (100%), and after that period until the present day the tongue-in-groove technique was performed in 11 cases (41%) and in the remaining 16 cases (59%) the caudal septal extension graft was performed. CONCLUSION: Cephalic malposition of the LLC is an important red flag of ENV insufficiency. This insufficiency should be treated by structuring the walls of the ENV. LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .


Subject(s)
Nasal Cartilages/surgery , Nasal Septum/surgery , Rhinoplasty/methods , Surgical Flaps/transplantation , Adolescent , Adult , Aged , Cohort Studies , Esthetics , Female , Humans , Male , Middle Aged , Nasal Cartilages/abnormalities , Nasal Obstruction/prevention & control , Nasal Septum/abnormalities , Preoperative Care/methods , Retrospective Studies , Risk Assessment , Treatment Outcome
13.
J Craniofac Surg ; 29(5): e475-e477, 2018 Jul.
Article in English | MEDLINE | ID: mdl-29561482

ABSTRACT

INTRODUCTION: Combined mid-face and nasal apparatus trauma injuries pose a significant challenge to airway patency (AW), in the immediate postoperative setting following fracture reduction. As such, the authors describe a modified technique with the goal of maintaining a patent nasal AW, while at the same time, minimizing nasopharyngeal bleeding and nasal AW edema-which can complicate patients requiring intermaxillary fixation (IMF) in the setting of pan-facial trauma. METHODS: A modified technique was devised to assist the reconstruction surgeon in avoiding the risks associated with tracheostomy placement. In an effort to avoid surgical AW complications and improve nasal AW patency in the setting of concurrent IMF and nasal trauma, the authors developed a 2-stage technique drawing upon knowledge from the literature and the authors' own experiences. TECHNIQUE: Following safe extubation, the authors insert open lumen nasal splints in both the nostrils, and suture them together to the nasal septum. If additional inner nasal support is required, polyvinyl alcohol nonabsorbable nasal packing dressing is covered with antibiotic ointment, and then placed within the nasal cavity lateral to the open lumen splints-as a way to further bolster the internal valve and mid-vault anatomy. DISCUSSION: Given the fact that traditional nasal packing with merocele/gauze dressing in concomitant to IMF reduced patients ability to ventilate, the authors felt that a modified technique should be applied. The authors' preferred materials in such patients are open lumen splint, which provides nasal AW patency along with some septum support accompanied by merocele dressing. The authors feel that by applying this technique they achieve dual objectives by supporting the traumatized nose and maintaining nasal AW patency.


Subject(s)
Maxillofacial Injuries/surgery , Nasal Obstruction/prevention & control , Nose/surgery , Splints , Bandages , Epistaxis/prevention & control , Fracture Fixation/adverse effects , Fracture Fixation, Internal/adverse effects , Humans , Maxillofacial Injuries/complications , Nasal Obstruction/etiology , Nasal Septum , Nose/injuries , Postoperative Period
14.
Am J Rhinol Allergy ; 31(6): 364-369, 2017 Nov 19.
Article in English | MEDLINE | ID: mdl-28927491

ABSTRACT

BACKGROUND: Nasal continuous positive airway pressure (CPAP) in moderate-to-severe cases of obstructive sleep apnea can cause nasal discomfort and other undesirable problems. OBJECTIVE: The aim of our study was to test the effects of sodium hyaluronate on nasal problems that patients experienced in their daily lives, sleepiness, nasal resistance to airflow, nasal mucociliary clearance, changes in inflammatory markers, and compliance to CPAP in three groups of patients with obstructive sleep apnea syndrome on CPAP therapy. METHODS: A total of 102 patients with a confirmed diagnosis of obstructive sleep apnea syndrome (apnea-hypopnea index [AHI] of ≥10/hour) were randomized into three treatment groups: (1) hyaluronate plus CPAP, (2) saline solution plus CPAP, and (3) CPAP-only groups. Outcome measures were the extent of improvement in the Mini Rhinoconjunctivitis Quality of Life Questionnaire (MiniRQLQ) mean scores, sleepiness, nasal resistance to airflow, nasal mucociliary clearance, changes in inflammatory markers, and compliance to CPAP. Significant improvement in each outcome measure was determined by comparing scores at baseline and after 4 weeks for each treatment group. RESULTS: Significant improvement in the MiniRQLQ overall mean score was observed both in the hyaluronate plus CPAP (p < 0.00001) and saline solution plus CPAP groups (p < 0.01), although the hyaluronate plus CPAP group had better improvement compared with the saline solution plus CPAP group (0.24 versus 0.12, respectively). An increase in nasal inflammatory markers and saccharin transit test score was observed in all three groups, although it was statistically lower in the hyaluronate plus CPAP group (all p < 0.001). CONCLUSION: Intranasal hyaluronate showed significant benefits in patients who received CPAP therapy, but future studies over a longer period of time after treatment should be performed to corroborate our findings.


Subject(s)
Continuous Positive Airway Pressure/adverse effects , Hyaluronic Acid/administration & dosage , Hyaluronic Acid/pharmacology , Mucociliary Clearance/drug effects , Sleep Apnea, Obstructive/therapy , Administration, Intranasal , Aged , Female , Humans , Male , Middle Aged , Mucociliary Clearance/physiology , Nasal Obstruction/prevention & control , Patient Compliance , Quality of Life , Sleep Apnea, Obstructive/physiopathology , Surveys and Questionnaires , Treatment Outcome
16.
J Craniofac Surg ; 28(7): e618-e621, 2017 Oct.
Article in English | MEDLINE | ID: mdl-28692500

ABSTRACT

OBJECTIVE: The authors aimed to investigate the effect of spreader grafts on nasal function in septorhinoplasty (SRP). METHODS: A prospective randomized double-blind study was conducted. Thirty patients who underwent SRP operation between October 2011 and January 2013 were divided into 2 equal groups randomly. Fifteen patients underwent SRP surgery without spreader graft technique (Group I) and 15 patients underwent SRP surgery with spreader grafts (Group II). Preoperative and postoperative evaluation included visual analog score (VAS) and acoustic rhinometry test. RESULTS: Visual analog scores and acoustic rhinometry measurements of Group I and Group II patients were compared. Statistically significant difference was found for VAS scores of both the sides of the nasal cavity (both before and after topical decongestion) (P < 0.05), except for the VAS on the right side of the nasal cavity before decongestion (P > 0.05). On acoustic rhinometry test the difference was statistically significant for minimal cross-sectional area (MCA) and volumetric values (VOL)-MCA1, MCA2, VOL1, VOL2 values on the left side of the nasal cavity (both before and after topical decongestion) (P < 0.05) but not on the right side of the nasal cavity (P > 0.05). CONCLUSIONS: Performing spreader graft technique in SRP surgery can prevent the narrowing of the internal nasal valve area after surgery and maintain adequate airway for respiration.


Subject(s)
Nasal Cartilages/transplantation , Nasal Obstruction/prevention & control , Nasal Septum/surgery , Postoperative Complications/prevention & control , Rhinoplasty/methods , Adult , Double-Blind Method , Female , Humans , Male , Nasal Obstruction/etiology , Postoperative Complications/etiology , Prospective Studies , Rhinometry, Acoustic , Rhinoplasty/adverse effects , Young Adult
17.
Vestn Otorinolaringol ; 82(2): 33-37, 2017.
Article in Russian | MEDLINE | ID: mdl-28514361

ABSTRACT

The objective of the present study was the analysis of the results of transethmoidal decompressive orbitotomy (TEDO) with the resection of the bone matrix of the medial and inferior orbital walls in the patients presenting with endocrine ophthalmopathy (EOP) with the purpose of reduction of the risk of development of this pathological conditions. A total of 51 patient with EOP at the stage of complete remission or pharmacotherapeutic compensation underwent transethmoidal decompressive medial orbitotomy in the ENT Clinic of 1 I.M. Sechenov First Moscow State Medical University during the period from 2006 to 2016. Twenty two of these patients presented with the unilateral process and 29 ones with bilateral exophthalmos. The surgical intervention was performed on the total of 80 eye orbits. The main complaints of the treated patients during the post-operative period included difficulties in nasal breathing (33%), dryness of the nose and crust formation (43%), discharge from the nose and along the posterior pharyngeal wall (15%), nasal bleeding (2%), pain in the forehead and maxillary region (8%), headache (2%). As far as the state of eyes and sight is concerned, 14 (27%) patients reported double vision at the primary gaze position while 6 others (12%) complained of the appearance of diplopia upon a change in the gaze position during the post-operative period. The post-operative endoscopic study revealed synechiae of different localization in the nasal cavity (47%), discharge from the maxillary sinuses (16%) and from the frontal sinus (2%). Eight (16%) patients were found to suffer from maxillary sinusitis, one had acute frontitis, and one sphenoidal sinus mucocelle. These complications were eliminated by pharmacotherapy and additional surgical interventions (2%). Analysis of the results of the study has demonstrated that the above complications were associated with the inadequate post-operative care for the nasal cavity, the excessively large size of the bone window formed during transethmoidal decompressive orbitotomy, resection of the inferior orbital wall, intrusion of the medial rectus muscle of the eye into the wide bone window. We evaluated the possible influence of the orbital soft tissues on the physiological parameters of the functioning of the paranasal sinuses in the post-operative period including blockade of the paranasal drainage pathways by the prolapsed orbital tissues. A few possible approaches to the reduction of the risk of post-operative complications are proposed. The authors emphasize the importance of the further improvement of the surgical treatment of endocrine ophthalmopathy.


Subject(s)
Decompression, Surgical , Diplopia , Graves Ophthalmopathy/surgery , Nasal Obstruction , Ophthalmologic Surgical Procedures , Postoperative Complications/prevention & control , Adult , Decompression, Surgical/adverse effects , Decompression, Surgical/methods , Diplopia/etiology , Diplopia/prevention & control , Female , Humans , Intraoperative Care/methods , Male , Nasal Obstruction/etiology , Nasal Obstruction/prevention & control , Ophthalmologic Surgical Procedures/adverse effects , Ophthalmologic Surgical Procedures/methods , Orbit/surgery , Outcome and Process Assessment, Health Care
18.
Laryngoscope ; 127(7): 1506-1512, 2017 07.
Article in English | MEDLINE | ID: mdl-28449210

ABSTRACT

BACKGROUND: Packing of the middle meatus and ethmoid cavities is a common practice in endoscopic sinus surgery (ESS), but its necessity recently has been challenged. The aim of this study was to formulate a decision-analysis model to determine the need for packing in ESS and identify variables affecting the decision. METHODS: A systematic review of the literature was conducted for all randomized control trials comparing packing to no packing in ESS, and a decision-analysis model was generated. Probabilities and utilities were derived from the literature. Sensitivity analysis was used to determine which variables most affected the model. RESULTS: No packing was associated with better expected utilities than packing. On sensitivity analysis, packing was preferred when the disutility of no packing outweighed the disutility of packing, and when the probability for synechiae was greater than 35% without packing or lower than 2% with packing. When the component of packing removal was subtracted from the overall disutility simulating absorbable packing, the results favored packing. CONCLUSION: Our decision-analysis model indicates that middle meatal packing is not advantageous for patients undergoing ESS. Absorbable packing materials have a less adverse effect on quality of life than nonabsorbable materials. LEVEL OF EVIDENCE: 1a. Laryngoscope, 127:1506-1512, 2017.


Subject(s)
Decision Support Techniques , Endoscopy/methods , Paranasal Sinuses/surgery , Rhinitis/surgery , Sinusitis/surgery , Adult , Decision Trees , Evidence-Based Medicine , Humans , Nasal Obstruction/etiology , Nasal Obstruction/prevention & control , Postoperative Complications/etiology , Postoperative Complications/prevention & control , Postoperative Hemorrhage/etiology , Postoperative Hemorrhage/prevention & control , Randomized Controlled Trials as Topic , Software , Tampons, Surgical
19.
JAMA Facial Plast Surg ; 19(4): 318-322, 2017 Jul 01.
Article in English | MEDLINE | ID: mdl-28334371

ABSTRACT

IMPORTANCE: Nasal reconstruction after Mohs surgery is a unique challenge in that it must satisfy both functional and aesthetic goals. Despite some advocacy in the literature for using structural reinforcement to achieve both functional and aesthetic outcomes in soft-tissue reconstruction, no study has validated this claim by comparing reconstruction with and without structural support. OBJECTIVE: To evaluate the effectiveness of and need for structural reinforcement when reconstructing the nasal alar and sidewall subunits. DESIGN, SETTING, AND PARTICIPANTS: This study was a retrospective review of the medical records of 190 patients 18 years or older who underwent nasal reconstruction after Mohs surgery in a tertiary care academic center between January 1, 2013, and August 31, 2015. Data on each patient included demographics, comorbidities, smoking status, details of the lesion, size of defect, subunits involved, and reconstructive technique. Patients were divided into 2 cohorts composed of those who had reconstruction with structural reinforcement (ie, cartilage grafting or suspension suture) and those with only soft-tissue reconstruction. Patients with nasal obstruction from the functional collapse of the reconstructed area and no history of nasal obstruction were included (n = 38). Patients who had a follow-up of less than 2 months, no alar or sidewall involvement, nasal obstruction secondary to turbinate hypertrophy, septal deflection or other nonstructural causes, and incomplete documentation for analysis were excluded (n = 102). MAIN OUTCOMES AND MEASURES: Rates of postoperative nasal obstruction secondary to nasal sidewall collapse and need for revision surgery. RESULTS: Of the 38 patients who met the inclusion criteria, 22 were men and 16 were women with a mean (range) age of 64.5 (35-92) years. Twenty-three patients (61%) underwent reconstruction by a facial plastic surgeon and 15 (39%) by 2 dermatologic surgeons. Three (8%) underwent reconstruction without reinforcement and experienced postoperative nasal obstruction. The mean size of reconstructed defects that resulted in nasal valve collapse was 2.1 cm in diameter (range, 1.2-2.6 cm). Defect size was associated with incidence of postoperative nasal obstruction. For defects greater than 1.2 cm in diameter, patients reconstructed without reinforcement had a statistically significant increase of nasal obstruction secondary to functional nasal collapse compared with patients reconstructed with reinforcement (3 of 14 [21%] vs 0 of 17; 95% CI, 0.005-0.358; P = .04). CONCLUSIONS AND RELEVANCE: Nasal defects greater than 1.2 cm in diameter and involving the alar and sidewalls were associated with lower incidence of postoperative nasal obstruction when a structural reinforcement technique was used in reconstruction. The findings of this study support the structural reinforcement of the nasal functional subunits during Mohs reconstructive surgery to achieve optimal outcomes. LEVEL OF EVIDENCE: 3.


Subject(s)
Cartilage/transplantation , Mohs Surgery , Nasal Obstruction/prevention & control , Postoperative Complications/prevention & control , Rhinoplasty/methods , Sutures , Adult , Aged , Aged, 80 and over , Esthetics , Female , Humans , Male , Middle Aged , Nasal Cartilages/surgery , Reoperation , Retrospective Studies
20.
Facial Plast Surg ; 33(1): 67-73, 2017 Feb.
Article in English | MEDLINE | ID: mdl-28226372

ABSTRACT

Reconstruction of full-thickness nasal defects has been the subject of surgical inquiry and innovation for over 2,000 years. The replacement of the internal nasal lining is a critical feature of complex nasal reconstruction. Successful reconstruction can prevent cicatricial contraction, external distortion, and internal stenosis. An array of reconstructive possibilities has been described, including cutaneous, mucosal, and fascial options. The challenge to the reconstructive surgeon is to select the repair that maximizes internal stability, while maintaining a patent nasal airway, minimizing morbidity, and meeting patient expectations. This article reviews the options available for the reconstruction of the intranasal lining.


Subject(s)
Nasal Mucosa/surgery , Rhinoplasty/methods , Surgical Flaps , Humans , Mouth Mucosa/transplantation , Nasal Obstruction/etiology , Nasal Obstruction/prevention & control , Nasal Septum/surgery , Rhinoplasty/adverse effects , Skin Transplantation
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