Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 1 de 1
Filter
Add more filters










Database
Language
Publication year range
1.
Pediatr Int ; 58(3): 237-240, 2016 Mar.
Article in English | MEDLINE | ID: mdl-26669790

ABSTRACT

The clinical course of congenital neonatal sepsis due to Streptococcus pneumoniae progresses rapidly and results in multiorgan failure with high mortality. The swift progression of the disease limits the timeframe for conventional treatment, which often requires waiting for antibiotics to show efficacy. Here, we describe the case of a very low-birthweight (VLBW) female infant with congenital sepsis due to S. pneumoniae who was treated with continuous hemodiafiltration (CHDF) and polymyxin B-immobilized fiber column-direct hemoperfusion (PMX-DHP). The infant was born at 30 weeks' gestation and diagnosed with hypotension, disseminated intravascular coagulation, and pulmonary hypertension. CHDF and PMX-DHP were initiated approximately 11 h after birth. Mean blood pressure, oxygenation, and blood interleukin-6 began to improve after dialysis commencement, and the patient survived with mild sequelae. Combined CHDF and PMX-DHP may be effective in treating VLBW infants with severe septic shock.


Subject(s)
Hemodiafiltration/methods , Infant, Low Birth Weight , Neonatal Sepsis/therapy , Pneumococcal Infections/therapy , Female , Follow-Up Studies , Humans , Infant, Newborn , Neonatal Sepsis/congenital , Neonatal Sepsis/microbiology , Pneumococcal Infections/congenital , Pneumococcal Infections/microbiology , Streptococcus pneumoniae/isolation & purification , Treatment Outcome
SELECTION OF CITATIONS
SEARCH DETAIL
...