ABSTRACT
No disponible
No disponible
Subject(s)
Humans , Male , Adult , Enterobacteriaceae/pathogenicity , Enterobacteriaceae Infections/etiology , Catheterization, Central Venous/adverse effects , Sarcoma, Ewing/complications , Cross Infection/etiology , Enterobacteriaceae/isolation & purification , Enterobacteriaceae Infections/microbiology , Sarcoma, Ewing/drug therapy , Sarcoma, Ewing/radiotherapy , Neoplasms, Bone Tissue/complications , Neoplasms, Bone Tissue/drug therapy , Neoplasms, Bone Tissue/radiotherapy , Antineoplastic Combined Chemotherapy Protocols/adverse effects , Lung Neoplasms/complications , Pelvic Bones/pathology , Immunocompromised HostABSTRACT
El papel de la radioterapia (RT) en los tumores de células gigantes es incierto. El tratamiento estándar es la cirugía, y el uso de adyuvancia es controvertido. Tras la presentación de un caso clínico se analiza la indicación de la RT en estos tumores y se lleva a cabo una revisión retrospectiva, con historias clínicas de pacientes diagnosticados en el Hospital General Universitario Gregorio Marañón con informe de tumor de células gigantes, análisis y discusión de la literatura. En los tumores de células gigantes en los que éstos se presentan en localizaciones difíciles de realizar una resección amplia, la RT debe ser el tratamiento estándar posterior a la biopsia, alcanzando excelentes tasas de respuesta local. La RT de rescate tras recidiva proporciona una alta tasa de control local sin añadir una morbilidad importante, por lo que debería indicarse como tratamiento en los casos mencionados o como tratamiento paliativo(AU)
The rol of the radiotherapy (RT) in the giant-cell tumor is unknown. The standart treatment is surgery and the use of adjuvant therapy is controversial. After a presentation of a clinical case, the indication of the RT is analyzed in these tumors, and a retrospective review is carried out with patients clinical histories diagnosed in the Hospital General Universitario Gregorio Marañón with report of tumor of giant cells, with analysis and discussion of the literature. In giant cells tumors in which the tumor appears in locations difficult to realize a wide resection, the radiotherapy must be the standard treatment after biopsy, reaching excellent rates of local response. Rescue RT, after recurrence, provides a high rate of local control without adding an additional important morbidity, by it should be indicated as treatment in the mentioned cases or as palliative treatment(AU)
Subject(s)
Humans , Male , Female , Adult , Neoplasms, Bone Tissue/radiotherapy , Giant Cell Tumor of Bone/radiotherapy , Doxorubicin/therapeutic use , Biopsy , Cementation , Neoplasms, Bone Tissue/diagnosis , Neoplasms, Bone Tissue , Giant Cell Tumor of Bone/physiopathology , Giant Cell Tumor of Bone , Retrospective Studies , Postoperative CareABSTRACT
OPINION STATEMENT: Primary spinal neoplasms are rare tumors that can lead to significant morbidity secondary to local bone destruction and invasion into adjacent neurological and vascular structures. These tumors represent a clinical challenge to even the most experienced physicians and require a multidisciplinary approach to ensure optimal patient outcomes. This review will discuss the most common primary bone tumors and focus on recent surgical, medical, and radiation treatment advances.
