[Comparison of molluscicidal cost and effectiveness between 5% niclosamide ethanolamine salt granules and 26% suspension concentrate of metalaldehyde and niclosamide ethanolamine salt].

OBJECTIVE: To compare the molluscicidal effects and cost-effectiveness of 5% niclosamide ethanolamine salt granules (NEG) and 26% suspension concentrate of metalaldehyde and niclosamide ethanolamine salt (MNSC) . METHODS: Two plots with high Oncomelania hupensis snail density were selected as research areas in Nanjing Chemical Industry Zone, and 5% NEG (40 g/m2) and 26% MNSC (40 g/m2) were used by the spraying method for snail control in the two plots, and their molluscicidal effects and cost-effectiveness were investigated and statistically analyzed. RESULTS: There was no significant difference between 5% NEG and 26% MNSC in the molluscicidal effects. The cost of 5% NEG was 1.25 times higher than that of 26% MN-SC per ten thousand square meters in snail control. CONCLUSIONS: The cost of 5% NEG is higher than that of 26% MNSC per ten thousand square meters in snail control. Their molluscicidal effects are similar.

[Effects and cost of four formulations of niclosamide ethanolamine salt in Oncomelania hupensis snail control in field].

OBJECTIVE: To investigate the effects and cost of four formulations of niclosamide ethanolamine salt in Oncomelania hupensis snail control in the field in marshland and lake regions, so as to provide the evidence for drawing up the plan of molluscicide using in schistosomiasis endemic areas. METHODS: One drainage channel and one channel without water in the same area with snails in Jiangling County, Jingzhou City were selected as the research fields. The drainage channel was divided into 9 sections, except one section as a blank control group where the natural death rate of snails was observed only, and the remaining 8 sections were taken as the observation groups, where different dosages of 4% niclosamide ethanolamine salt powder, 5% niclosamide ethanolamine salt granules, 25% niclosamide ethanolamine salt suspending agent, 26% metaldehyde and niclosamide ethanolamine salt suspending agent, and 50% niclosamide ethanolamine salt wettable powder were used respectively. The channel without water were divided into 4 sections, except one section as a blank control group, the other 3 segments were taken as the observation groups, where 4% niclosamide ethanolamine salt powder, 5% niclosamide ethanolamine salt granules, and 50% niclosamide ethanolamine salt wettable powder were used respectively. Before and after spraying molluscicide for 7 days and 15 days, the system sampling method was used to observe the effects of snail control. Meanwhile, the unit cost method was used to calculate the costs of the different mulluscicide formulations abovementioned in unit area (1 m2). RESULTS: In the field at the drainage channel, the snail mortality rates of the groups spraying 4% niclosamide ethanolamine salt powder (50 g/m2), 5% niclosamide ethanolamine salt granules (40 g/m2), 25% niclosamide ethanolamine suspending agent, 26% metaldehyde and niclosamide ethanolamine salt suspending agent, and 50% niclosamide ethanolamine salt wettable powder (2 g/m2 and 4 g/m2) for 7 days were 79.52%97.87%, while the rates after spraying for 15 days were 71.00%-96.30%, and compared with those before spraying, the differences were statistically significant (all P < 0.01). For the groups spraying with 2 g/m2 or 4 g/m2 suspending agent as well as wettable powder for 7 days, the snail mortality rates were significantly different (both P < 0.05). In the field at the channel without water, the snail mortality rates of the 3 observation groups after spraying molluscicide for 7 days were 97.14%-100%, while for 15 days were 94.32 %-100%, and compared with the rates before spraying, all the differences were statistically significant (all P < 0.01). The unit costs per 1 m2 of the molluscicide abovementioned were ranged from 0.280 Yuan to 0.416 Yuan. CONCLUSIONS: In marshland area inside embankment, the molluscicide formulations of the powder and granule are suitable for the environments without water or with instability water level, while the molluscicide formulations of the suspended agents and wettable powder are suitable for the water environment. Though the unit cost of powder is the lowest, the molluscicide in this formulation flies away seriously.