[Nitric oxide system in blood of newborn infants at elevated risk of perinatal pathology].

The study was designed to evaluate activity of the blood nitric oxide (NO) system in newborns at high risk of perinatal pathology. The observed rise in NO production should be regarded as a compensatory and adaptive reaction facilitating the maintenance of microcirculation and hemodynamics in organs and their systems of newborn infants. The inter-relation and inter-dependence between NO levels and enzymatic activities (NOS, HP, O2-, ONOO-, and SOD) make up an integral pathogenetic mechanism determining severity and progress of affection of vitally important organs and systems as well as associated clinical symptoms in full-term and premature infants at high perinatal risk.