1.
Food Chem Toxicol
; 45 Suppl 1: S276-9, 2007.
Article
in English
| MEDLINE
| ID: mdl-18022306
ABSTRACT
A toxicologic and dermatologic review of methyl-alpha-ionone when used as a fragrance ingredient is presented.
Subject(s)
Norisoprenoids/toxicity , Perfume/toxicity , Animals , Consumer Product Safety , Dose-Response Relationship, Drug , Humans , Mutagenicity Tests , Mutagens/classification , Mutagens/pharmacokinetics , Mutagens/toxicity , Norisoprenoids/classification , Norisoprenoids/pharmacokinetics , Perfume/classification , Perfume/pharmacokinetics , Risk Assessment , Skin/drug effects , Skin/metabolism , Skin Absorption , Skin Irritancy Tests , Skin Tests
2.
Food Chem Toxicol
; 45 Suppl 1: S280-9, 2007.
Article
in English
| MEDLINE
| ID: mdl-18037210
ABSTRACT
A toxicologic and dermatologic review of alpha-iso-methylionone when used as a fragrance ingredient is presented.
Subject(s)
Norisoprenoids/toxicity , Perfume/toxicity , Allergens/classification , Allergens/pharmacokinetics , Allergens/toxicity , Animals , Consumer Product Safety , Dose-Response Relationship, Drug , Humans , Norisoprenoids/classification , Norisoprenoids/pharmacokinetics , Noxae/classification , Noxae/pharmacokinetics , Noxae/toxicity , Perfume/classification , Perfume/pharmacokinetics , Reproduction/drug effects , Risk Assessment , Skin/drug effects , Skin/metabolism , Skin Absorption , Skin Irritancy Tests , Skin Tests , Toxicity Tests
3.
Food Chem Toxicol
; 45 Suppl 1: S192-8, 2007.
Article
in English
| MEDLINE
| ID: mdl-18037213
ABSTRACT
A toxicologic and dermatologic review of cis-beta-damascone when used as a fragrance ingredient is presented.
Subject(s)
Norisoprenoids/toxicity , Perfume/toxicity , Allergens/classification , Allergens/pharmacokinetics , Allergens/toxicity , Animals , Consumer Product Safety , Humans , Irritants/classification , Irritants/pharmacology , Irritants/toxicity , Norisoprenoids/classification , Norisoprenoids/pharmacokinetics , Perfume/classification , Perfume/pharmacokinetics , Risk Assessment , Skin/drug effects , Skin/metabolism , Skin/pathology , Skin Absorption , Skin Irritancy Tests , Skin Tests , Stereoisomerism , Toxicity Tests
4.
Food Chem Toxicol
; 45 Suppl 1: S211-5, 2007.
Article
in English
| MEDLINE
| ID: mdl-18022745
ABSTRACT
A toxicologic and dermatologic review of trans,trans-delta-damascone when used as a fragrance ingredient is presented.
Subject(s)
Norisoprenoids/toxicity , Perfume/toxicity , Allergens/classification , Allergens/pharmacokinetics , Allergens/toxicity , Animals , Consumer Product Safety , Dose-Response Relationship, Drug , Humans , Norisoprenoids/classification , Norisoprenoids/pharmacokinetics , Perfume/classification , Perfume/pharmacokinetics , Risk Assessment , Skin/drug effects , Skin/metabolism , Skin Absorption , Skin Tests , Stereoisomerism , Toxicity Tests
5.
Food Chem Toxicol
; 45 Suppl 1: S263-6, 2007.
Article
in English
| MEDLINE
| ID: mdl-18023518
ABSTRACT
A toxicologic and dermatologic review of isodamascone when used as a fragrance ingredient is presented.
Subject(s)
Norisoprenoids/toxicity , Perfume/toxicity , Administration, Cutaneous , Consumer Product Safety , Humans , Norisoprenoids/classification , Norisoprenoids/pharmacokinetics , Perfume/classification , Perfume/pharmacokinetics , Risk Assessment , Skin/metabolism , Skin Absorption , Stereoisomerism
6.
Food Chem Toxicol
; 45 Suppl 1: S294-6, 2007.
Article
in English
| MEDLINE
| ID: mdl-18031882
ABSTRACT
A toxicologic and dermatologic review of 6-methyl-beta-ionone when used as a fragrance ingredient is presented.
Subject(s)
Norisoprenoids/toxicity , Perfume/toxicity , Administration, Cutaneous , Animals , Consumer Product Safety , Humans , Norisoprenoids/classification , Norisoprenoids/pharmacokinetics , Perfume/pharmacokinetics , Risk Assessment , Skin/metabolism , Skin Absorption
7.
Food Chem Toxicol
; 45 Suppl 1: S241-7, 2007.
Article
in English
| MEDLINE
| ID: mdl-18031886
ABSTRACT
A toxicologic and dermatologic review of beta-ionone when used as a fragrance ingredient is presented.
Subject(s)
Norisoprenoids/toxicity , Perfume/toxicity , Animals , Consumer Product Safety , Dose-Response Relationship, Drug , Humans , Irritants/classification , Irritants/pharmacokinetics , Irritants/toxicity , Norisoprenoids/classification , Norisoprenoids/pharmacokinetics , Perfume/classification , Perfume/pharmacokinetics , Risk Assessment , Skin/drug effects , Skin/metabolism , Skin/pathology , Skin Irritancy Tests , Skin Tests , Teratogens/classification , Teratogens/pharmacokinetics , Teratogens/toxicity , Toxicity Tests
8.
Food Chem Toxicol
; 45 Suppl 1: S297-9, 2007.
Article
in English
| MEDLINE
| ID: mdl-18031893
ABSTRACT
A toxicologic and dermatologic review of iso-methyl-beta-ionone when used as a fragrance ingredient is presented.
Subject(s)
Norisoprenoids/toxicity , Perfume/toxicity , Administration, Cutaneous , Animals , Consumer Product Safety , Humans , Norisoprenoids/classification , Norisoprenoids/pharmacokinetics , Perfume/pharmacokinetics , Risk Assessment , Skin/metabolism , Skin Absorption
9.
Food Chem Toxicol
; 45 Suppl 1: S199-204, 2007.
Article
in English
| MEDLINE
| ID: mdl-18031894
ABSTRACT
A toxicologic and dermatologic review of trans-beta-damascone when used as a fragrance ingredient is presented.
Subject(s)
Norisoprenoids/toxicity , Perfume/toxicity , Allergens/classification , Allergens/pharmacokinetics , Allergens/toxicity , Animals , Consumer Product Safety , Dose-Response Relationship, Drug , Humans , Lymph Nodes/drug effects , Lymph Nodes/pathology , Norisoprenoids/classification , Norisoprenoids/pharmacokinetics , Perfume/classification , Perfume/pharmacokinetics , Risk Assessment , Skin/drug effects , Skin/metabolism , Skin/pathology , Skin Absorption , Skin Irritancy Tests , Skin Tests , Stereoisomerism , Toxicity Tests
10.
Food Chem Toxicol
; 45 Suppl 1: S251-7, 2007.
Article
in English
| MEDLINE
| ID: mdl-18031895
ABSTRACT
A toxicologic and dermatologic review of ionone when used as a fragrance ingredient is presented.
Subject(s)
Norisoprenoids/toxicity , Perfume/toxicity , Animals , Consumer Product Safety , Dose-Response Relationship, Drug , Humans , Norisoprenoids/classification , Norisoprenoids/pharmacokinetics , Noxae/classification , Noxae/pharmacokinetics , Noxae/toxicity , Perfume/classification , Perfume/pharmacokinetics , Risk Assessment , Skin/drug effects , Skin/metabolism , Skin/pathology , Skin Absorption , Skin Irritancy Tests , Skin Tests , Toxicity Tests
11.
Food Chem Toxicol
; 45 Suppl 1: S225-8, 2007.
Article
in English
| MEDLINE
| ID: mdl-18031899
ABSTRACT
A toxicologic and dermatologic review of dihydro-beta-ionone when used as a fragrance ingredient is presented.
Subject(s)
Norisoprenoids/toxicity , Perfume/toxicity , Animals , Consumer Product Safety , Dose-Response Relationship, Drug , Humans , Irritants/classification , Irritants/pharmacokinetics , Irritants/toxicity , Mutagenicity Tests , Mutagens/classification , Mutagens/pharmacokinetics , Mutagens/toxicity , Norisoprenoids/classification , Norisoprenoids/pharmacokinetics , Perfume/classification , Perfume/pharmacokinetics , Risk Assessment , Skin/drug effects , Skin/metabolism , Skin Absorption , Skin Irritancy Tests , Skin Tests
12.
Food Chem Toxicol
; 45 Suppl 1: S179-87, 2007.
Article
in English
| MEDLINE
| ID: mdl-18031900
ABSTRACT
A toxicologic and dermatologic review of alpha-damascone when used as a fragrance ingredient is presented.
Subject(s)
Norisoprenoids/toxicity , Perfume/toxicity , Allergens/classification , Allergens/pharmacokinetics , Allergens/toxicity , Animals , Consumer Product Safety , Dose-Response Relationship, Drug , Female , Humans , Irritants/classification , Irritants/pharmacokinetics , Irritants/toxicity , Male , Mutagenicity Tests , Mutagens/classification , Mutagens/pharmacokinetics , Mutagens/toxicity , Norisoprenoids/classification , Norisoprenoids/pharmacokinetics , Perfume/classification , Perfume/pharmacokinetics , Risk Assessment , Skin/drug effects , Skin/metabolism , Skin Absorption , Skin Irritancy Tests , Skin Tests
13.
Food Chem Toxicol
; 45 Suppl 1: S248-50, 2007.
Article
in English
| MEDLINE
| ID: mdl-18031901
ABSTRACT
A toxicologic and dermatologic review of trans-beta-Ionone when used as a fragrance ingredient is presented.
Subject(s)
Norisoprenoids/toxicity , Perfume/toxicity , Administration, Cutaneous , Consumer Product Safety , Humans , Norisoprenoids/classification , Norisoprenoids/pharmacokinetics , Perfume/pharmacokinetics , Risk Assessment , Skin/metabolism , Skin Absorption , Stereoisomerism
14.
Food Chem Toxicol
; 45 Suppl 1: S205-10, 2007.
Article
in English
| MEDLINE
| ID: mdl-18031903
ABSTRACT
A toxicologic and dermatologic review of delta-damascone when used as a fragrance ingredient is presented.
Subject(s)
Norisoprenoids/toxicity , Perfume/toxicity , Allergens/classification , Allergens/pharmacokinetics , Allergens/toxicity , Animals , Consumer Product Safety , Dose-Response Relationship, Drug , Humans , Lymph Nodes/drug effects , Lymph Nodes/pathology , Norisoprenoids/classification , Norisoprenoids/pharmacokinetics , Perfume/classification , Perfume/pharmacokinetics , Risk Assessment , Skin/drug effects , Skin/metabolism , Skin Absorption , Skin Irritancy Tests , Skin Tests , Toxicity Tests
15.
Food Chem Toxicol
; 45 Suppl 1: S300-7, 2007.
Article
in English
| MEDLINE
| ID: mdl-18031904
ABSTRACT
A toxicologic and dermatologic review of methyl ionone when used as a fragrance ingredient is presented.
Subject(s)
Norisoprenoids/toxicity , Perfume/toxicity , Animals , Consumer Product Safety , Dose-Response Relationship, Drug , Humans , Irritants/classification , Irritants/pharmacokinetics , Irritants/toxicity , Lymph Nodes/drug effects , Lymph Nodes/pathology , Mutagenicity Tests , Mutagens/pharmacokinetics , Mutagens/pharmacology , Mutagens/toxicity , Norisoprenoids/classification , Norisoprenoids/pharmacokinetics , Perfume/classification , Perfume/pharmacokinetics , Photosensitizing Agents/classification , Photosensitizing Agents/pharmacokinetics , Photosensitizing Agents/toxicity , Risk Assessment , Skin/drug effects , Skin/metabolism , Skin Absorption , Skin Tests
16.
Food Chem Toxicol
; 45 Suppl 1: S221-4, 2007.
Article
in English
| MEDLINE
| ID: mdl-18031905
ABSTRACT
A toxicologic and dermatologic review of dihydro-alpha-ionone when used as a fragrance ingredient is presented.
Subject(s)
Norisoprenoids/toxicity , Perfume/toxicity , Administration, Cutaneous , Animals , Consumer Product Safety , Humans , Irritants/classification , Irritants/pharmacokinetics , Irritants/toxicity , Norisoprenoids/classification , Norisoprenoids/pharmacokinetics , Perfume/classification , Perfume/pharmacokinetics , Risk Assessment , Skin/drug effects , Skin/metabolism , Skin/pathology , Skin Absorption , Skin Irritancy Tests , Skin Tests , Toxicity Tests
17.
Food Chem Toxicol
; 45 Suppl 1: S272-5, 2007.
Article
in English
| MEDLINE
| ID: mdl-18031907
ABSTRACT
A toxicologic and dermatologic review of alpha-irone when used as a fragrance ingredient is presented.
Subject(s)
Norisoprenoids/toxicity , Perfume/toxicity , Allergens/classification , Allergens/pharmacokinetics , Allergens/toxicity , Animals , Carcinogenicity Tests , Carcinogens/classification , Carcinogens/pharmacokinetics , Carcinogens/toxicity , Consumer Product Safety , Dose-Response Relationship, Drug , Humans , Irritants/classification , Irritants/pharmacokinetics , Irritants/toxicity , Norisoprenoids/classification , Norisoprenoids/pharmacokinetics , Perfume/classification , Perfume/pharmacokinetics , Risk Assessment , Skin/drug effects , Skin/metabolism , Skin/pathology , Skin Absorption , Skin Irritancy Tests , Skin Tests
18.
Food Chem Toxicol
; 45 Suppl 1: S216-20, 2007.
Article
in English
| MEDLINE
| ID: mdl-18031909
ABSTRACT
A toxicologic and dermatologic review of gamma-damascone when used as a fragrance ingredient is presented.
Subject(s)
Norisoprenoids/toxicity , Perfume/toxicity , Allergens/classification , Allergens/pharmacokinetics , Allergens/toxicity , Animals , Consumer Product Safety , Dose-Response Relationship, Drug , Humans , Irritants/classification , Irritants/pharmacokinetics , Irritants/toxicity , Lymph Nodes/drug effects , Lymph Nodes/pathology , Norisoprenoids/classification , Norisoprenoids/pharmacokinetics , Perfume/classification , Perfume/pharmacokinetics , Risk Assessment , Skin/drug effects , Skin/metabolism , Skin Absorption , Skin Irritancy Tests , Skin Tests , Toxicity Tests
19.
Food Chem Toxicol
; 45 Suppl 1: S229-31, 2007.
Article
in English
| MEDLINE
| ID: mdl-18031912
ABSTRACT
A toxicologic and dermatologic review of dihydro-gamma-ionone when used as a fragrance ingredient is presented.
Subject(s)
Norisoprenoids/toxicity , Perfume/toxicity , Animals , Consumer Product Safety , Dose-Response Relationship, Drug , Humans , Local Lymph Node Assay , Lymph Nodes/drug effects , Lymph Nodes/pathology , Mice , Mice, Inbred CBA , Norisoprenoids/classification , Norisoprenoids/pharmacokinetics , Perfume/classification , Perfume/pharmacokinetics , Risk Assessment , Skin Absorption
20.
Food Chem Toxicol
; 45 Suppl 1: S267-71, 2007.
Article
in English
| MEDLINE
| ID: mdl-18031913
ABSTRACT
A toxicologic and dermatologic review of alpha-isodamascone when used as a fragrance ingredient is presented.
