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1.
J Matern Fetal Neonatal Med ; 35(25): 9857-9863, 2022 Dec.
Article in English | MEDLINE | ID: mdl-35403539

ABSTRACT

INTRODUCTION: Obstructive ureterocele is an intravesical cystic dilation of the distal end of the ureter associated with anhidramnios and dilation of both renal pelvises. METHODS: This is a case-series of prenatally diagnosed ureterocele. Cases were selected at a third level reference hospital in Monterrey Mexico between 2010 and 2018. Eligible patients for fetal therapy were selected when bilateral hydronephrosis and severe oligohydramnios were found before 26+0 weeks of gestation. The fetal intervention comprised an ultrasound-guided needle laser technique for ureterocele ablation. RESULTS: There were six cases of prenatal diagnosed of ureterocele, two cases showed anhidramnios at 23 weeks of gestation and were considered obstructive ureterocele. For these two cases, fetal surgery was performed using laser ablation of the ureterocele through an ultrasound-guided needle. In both, the urinary tract was decompressed, and the volume of amniotic fluid improved allowing to carry both pregnancies until term, one of them vaginally and the other by cesarean section. In the postnatal follow-up of both cases, the first neonate died due to neonatal asphyxia at 48-hours, and the second neonate required removal of the abnormal collecting system. CONCLUSIONS: The use of ultrasound-guided laser ablation for the decompression of obstructive ureterocele is a safe and feasible technique in extremely premature fetuses that could allow survival of the affected fetus until term. Patients receiving an early prenatal diagnosis of obstructive ureterocele may benefit from fetal therapy to reduce the risk of lung hypoplasia and stillbirth.Established factsPrenatal mortality of bilateral obstructive ureterocele is up to 45%.Only a few techniques have been described for the management of prenatally bilateral obstructive ureterocele; among them, the puncturing of the ureterocele which may require more than one intervention during fetal, laser by fetoscopy which may increase the risk of postoperative complications, and ultrasound-guided laser fulguration which seems to be effective and safe.Novel insightsThe present is the first description of a case series on ureteroceles comprising two ultrasound-guided laser therapy as an effective treatment for bilateral obstructive ureterocele requiring a single intervention.The use of ultrasound-guided laser in obstructive cases avoids fatality and lung hypoplasia due to severe oligohydramnios. Still, the neonatal prognosis of the affected side at two years of age remains unchanged.


Subject(s)
Laser Therapy , Oligohydramnios , Ureterocele , Infant, Newborn , Humans , Pregnancy , Female , Ureterocele/diagnostic imaging , Ureterocele/surgery , Ureterocele/complications , Oligohydramnios/diagnostic imaging , Oligohydramnios/surgery , Cesarean Section , Fetoscopy , Laser Therapy/methods , Lasers , Ultrasonography, Interventional
2.
Medicine (Baltimore) ; 100(2): e24051, 2021 Jan 15.
Article in English | MEDLINE | ID: mdl-33466158

ABSTRACT

RATIONALE: Spontaneous uterine rupture during pregnancy, occurring most often during labor in the context of a scarred uterus, is a serious obstetric complication. Perhaps even more serious because of its extreme rarity, spontaneous uterine rupture in a primigravid patient with an unscarred gravid uterus would be essentially unexpected. Clinical manifestations of unscarred uterine ruptures are nonspecific and can be confusing, making a correct early diagnosis very difficult. PATIENT CONCERNS: A primigravid woman at 27 weeks of gestation presented to our hospital with acute oligohydramnios. Ultrasound examination at her local hospital revealed oligohydramnios that had not been present 1 week previously. A specific cause of the acute oligohydramnios, however, was not established. DIAGNOSIS: Upon transfer to our hospital, the patient was hemodynamically stable without abdominal tenderness or peritoneal signs. Transabdominal ultrasound was repeated and confirmed oligohydramnios and seroperitoneum. The fetal heart rate was in the normal range, and blood tests revealed a low hemoglobin level of 91 g/L, which had been normal recently. A repeat sonogram after admission found that there was almost no amniotic fluid within the uterine cavity, and there was increased peritoneal fluid. Repeat hemoglobin showed a further decrease to 84 g/L. The combination of increased free abdominal fluid, lack of intrauterine fluid, and acutely decreasing hemoglobin strongly suggested uterine rupture with active intraperitoneal bleeding. INTERVENTIONS: Emergent laparotomy was performed, and a male infant was delivered. Comprehensive abdominal exploration revealed a rupture in the right uterine cornua with ongoing slow bleeding, through which a portion of the amniotic sac protruded into the abdominal cavity. OUTCOMES: The laceration was repaired, the patient and neonate recovered without complications, and were discharged 5 days postoperatively. LESSONS: An increased awareness of the rare but real possibility of spontaneous uterine rupture in a primigravid patient with no prior uterine scarring helped to establish an earlier diagnosis. Obstetricians should consider this possibility in pregnant females, even in the absence of risk factors and in early gestational age, when sudden unexplained clinical manifestations, such as acute oligohydramnios, are encountered.


Subject(s)
Oligohydramnios/epidemiology , Uterine Rupture/epidemiology , Adult , Female , Gestational Age , Gravidity , Humans , Oligohydramnios/surgery , Pregnancy , Uterine Rupture/surgery
3.
Ultrasound Obstet Gynecol ; 54(4): 500-505, 2019 Oct.
Article in English | MEDLINE | ID: mdl-30977189

ABSTRACT

OBJECTIVE: Congenital lower urinary tract obstruction (LUTO) is a rare condition with high perinatal mortality and morbidity when associated with severe oligohydramnios or anhydramnios in the second trimester of pregnancy. Severe pulmonary hypoplasia and end-stage renal disease are the underlying causes of poor neonatal outcome in these cases. However, little is known about the subset of fetal LUTO that is associated with a normal volume of amniotic fluid at midgestation. The objective of the current study was to describe the natural history, underlying causes, survival and postnatal renal function outcomes in pregnancies with fetal LUTO and normal amniotic fluid volume during the second trimester of pregnancy. METHODS: This was a retrospective study of all pregnancies with fetal LUTO and normal amniotic fluid volume in the second trimester that received prenatal and postnatal care at our quaternary care institution between 2013 and 2017. Data on demographic characteristics, fetal interventions, perinatal survival, need for neonatal respiratory support, postnatal renal function and need for dialysis at the age of 1 and 24 months were analyzed. RESULTS: Of the 18 fetuses that met the study criteria, 17 (94.4%) survived the perinatal period. Eleven (61.1%) pregnancies developed oligohydramnios in the third trimester, six of which were eligible for and underwent fetal intervention with vesicoamniotic shunt placement, which was performed successfully in all six cases. Two (11.1%) neonates required respiratory support owing to pulmonary hypoplasia. At the age of 2 years, 14 children had follow-up information available, two (14.3%) of whom had normal renal function, eight (57.1%) had developed some degree of chronic kidney disease (Stage 1-4) and four (28.6%) had developed end-stage renal disease (ESRD), including two who had already manifested ESRD in the neonatal period. CONCLUSIONS: Most fetuses diagnosed prenatally with LUTO that is associated with a normal volume of amniotic fluid at midgestation will have a favorable outcome in terms of perinatal survival and few will need long-term respiratory support. However, these children are still at increased risk for chronic renal disease, ESRD and need for renal replacement therapy. Larger multicenter studies are needed to characterize the prenatal factors associated with postnatal renal function, and to investigate the role of fetal intervention in the group of fetuses that present with late-onset oligohydramnios and evidence of preserved fetal renal function. Copyright © 2019 ISUOG. Published by John Wiley & Sons Ltd.


Subject(s)
Fetal Diseases/diagnostic imaging , Urethral Obstruction/diagnostic imaging , Urologic Diseases/diagnostic imaging , Adult , Amniotic Fluid/diagnostic imaging , Child, Preschool , Female , Fetal Diseases/pathology , Fetal Diseases/surgery , Humans , Infant , Infant, Newborn , Oligohydramnios/diagnostic imaging , Oligohydramnios/surgery , Perinatal Mortality , Pregnancy , Pregnancy Trimester, Second , Renal Insufficiency, Chronic/diagnosis , Renal Insufficiency, Chronic/etiology , Renal Insufficiency, Chronic/therapy , Retrospective Studies , Risk Assessment , Ultrasonography/methods , Urethral Obstruction/congenital , Urethral Obstruction/mortality , Urologic Diseases/congenital
4.
Arch Gynecol Obstet ; 299(3): 765-771, 2019 03.
Article in English | MEDLINE | ID: mdl-30730010

ABSTRACT

OBJECTIVE: To compare pregnancy outcomes following induction of labor with prostaglandins versus extra-amniotic balloon catheter indicated for term isolated oligohydramnios. STUDY DESIGN: Retrospective cohort study of all women who underwent induction of labor due to term isolated oligohydramnios at a university affiliated medical center (2007-2016). The cohort was divided into two subgroups, according to induction method: vaginal prostaglandins E2 versus extra-amniotic balloon catheter. Primary outcomes were successful cervical ripening, defined as a Bishop score ≥ 8, and vaginal delivery rate. Secondary outcomes were neonatal adverse events. RESULTS: Five hundred and ten women were included, of whom 454 (89%) underwent induction by prostaglandins and 56 (11%) by extra-amniotic balloon. Cervical ripening success rate was significantly higher in the prostaglandins group (89.4 vs. 76.79%, p = 0.006), as was the rate of vaginal delivery (77.53 vs. 48.21%, p < 0.0001). Induction with prostaglandins remained superior to extra-amniotic balloon in vaginal delivery rate following adjustment to potential confounders (aOR 3.470, 95% CI 1.296-9.296, p < 0.0001). Neonates delivered following induction with extra-amniotic balloon catheter were more often admitted to the neonatal intensive care unit (14.55 vs. 3.39%, p = 0.002). CONCLUSION: Both prostaglandins and extra-amniotic balloon catheter are reasonable interventions for isolated term oligohydramnios. Prostaglandins were superior to extra-amniotic balloon both in cervical ripening success and in vaginal delivery rates.


Subject(s)
Labor, Induced/methods , Oligohydramnios/surgery , Prostaglandins/therapeutic use , Adult , Female , Humans , Pregnancy , Pregnancy Outcome , Prostaglandins/pharmacology , Retrospective Studies
5.
Fetal Diagn Ther ; 45(1): 21-27, 2019.
Article in English | MEDLINE | ID: mdl-29462812

ABSTRACT

INTRODUCTION: We aimed to clarify the survival rate without brain abnormalities (BA) after fetoscopic laser photoco-agulation (FLP) for monochorionic diamniotic twin gestations (MCDA) with selective intrauterine growth restriction (sIUGR) accompanied by abnormal umbilical artery (UA) Doppler waveforms and isolated oligohydramnios in the sIUGR twin. MATERIALS AND METHODS: This retrospective study included 52 cases that underwent FLP. The main outcome was survival rate without BA of the twins at age 28 days. BA was defined as severe intraventricular hemorrhage and periventricular leukomalacia on postnatal ultrasonography. RESULTS: Median gestational age at FLP was 20 (16-24) weeks. Ten cases were classified as type III based on Doppler for the UA. For all cases, including 20 cases of anterior placenta, FLP was completed without major intraoperative complications. Amnioinfusion was required in 49 cases for better fetoscopic visualization. Fetal loss occurred in 29 sIUGR twins and two larger twins, whereas one larger twin experienced neonatal death. Survival rates without BA were 44% (n = 23) for sIUGR twins and 94% (n = 49) for the larger twins. DISCUSSION: FLP for MCDA with sIUGR presenting with oligohydramnios in the sIUGR twin might be considered a prenatal treatment option.


Subject(s)
Brain/diagnostic imaging , Diseases in Twins/surgery , Fetal Growth Retardation/surgery , Fetoscopy , Laser Coagulation , Oligohydramnios/surgery , Twins, Monozygotic , Ultrasonography , Diseases in Twins/diagnostic imaging , Diseases in Twins/mortality , Diseases in Twins/physiopathology , Female , Fetal Death , Fetal Growth Retardation/diagnostic imaging , Fetal Growth Retardation/mortality , Fetal Growth Retardation/physiopathology , Fetoscopy/adverse effects , Fetoscopy/mortality , Gestational Age , Humans , Infant, Newborn , Japan , Laser Coagulation/adverse effects , Laser Coagulation/mortality , Live Birth , Oligohydramnios/diagnostic imaging , Oligohydramnios/mortality , Oligohydramnios/physiopathology , Perinatal Death , Predictive Value of Tests , Pregnancy , Retrospective Studies , Treatment Outcome , Ultrasonography, Doppler, Color , Ultrasonography, Prenatal/methods
6.
JNMA J Nepal Med Assoc ; 56(213): 871-874, 2018.
Article in English | MEDLINE | ID: mdl-31065123

ABSTRACT

INTRODUCTION: Cesarean section is one of the common obstetric procedures done when the childbirth is not anticipated to occur by the normal vaginal delivery. There has been increased rate of cesarean section globally as well as in our country in recent decades. METHODS: This descriptive cross-sectional study has been carried out by reviewing a year of data from maternity ward of Paschimanchal Community Hospital, Prithvi Chowk, Pokhara. The total number of delivery, their modes either vaginal or cesarean, indications for the cesarean section and their outcomes were analyzed. The obtained data was entered and analyzed in Microsoft Excel. RESULTS: Total of 257 cases underwent delivery during the study period and 174 (63.27%) were by cesarean section. Oligohydramnios is the most common indication for cesarean section. Around 25 (14.36%) of the women underwent repeat cesarean section. CONCLUSIONS: The rate of cesarean section was quite high in our study and further studies are recommended for understanding of causes and other associated factors with it.


Subject(s)
Cesarean Section/statistics & numerical data , Hospitals, Community/statistics & numerical data , Cephalopelvic Disproportion/surgery , Cesarean Section, Repeat/statistics & numerical data , Cross-Sectional Studies , Dystocia/surgery , Female , Fetal Distress/surgery , Humans , Nepal , Oligohydramnios/surgery , Pregnancy
7.
PLoS One ; 12(11): e0188074, 2017.
Article in English | MEDLINE | ID: mdl-29155840

ABSTRACT

BACKGROUND AND METHODS: Caesarean section (C-section) is a major obstetric intervention for saving lives of women and their newborns from pregnancy and childbirth related complications. Un-necessary C-sections may have adverse impact upon maternal and neonatal outcomes. In Bangladesh there is paucity of data on clinical indication of C-section at population level. We conducted a retrospective study in icddr,b Health and Demographic Surveillance System (HDSS) area of Matlab to look into the indications and determinants of C-sections. All resident women in HDSS service area who gave birth in 2013 with a known birth outcome, were included in the study. Women who underwent C-section were identified from birth and pregnancy files of HDSS and their indication for C-section were collected reviewing health facility records where the procedure took place, supplemented by face-to-face interview of mothers where data were missing. Indications of C-section were presented as frequency distribution and further divided into different groups following 3 distinct classification systems. Socio-demographic predictors were explored following statistical method of binary logistic regression. FINDINGS: During 2013, facility delivery rate was 84% and population based C-section rate was 35% of all deliveries in icddr,b service area. Of all C-sections, only 1.4% was conducted for Absolute Maternal Indications (AMIs). Major indications of C-sections included: repeat C-section (24%), foetal distress (21%), prolonged labour (16%), oligohydramnios (14%) and post-maturity (13%). More than 80% C-sections were performed in for-profit private facilities. Probability of C-section delivery increased with improved socio-economic status, higher education, lower birth order, higher age, and with more number of Antenatal Care use and presence of bad obstetric history. Eight maternal deaths occurred, of which five were delivered by C-section. CONCLUSIONS: C-section rate in this area was much higher than national average as well as global recommendations. Very few of C-sections were undertaken for AMIs. Routine monitoring of clinical indication of C-section in public and private facilities is needed to ensure rational use of the procedure.


Subject(s)
Cesarean Section/statistics & numerical data , Fetal Distress/epidemiology , Medical Overuse/statistics & numerical data , Oligohydramnios/epidemiology , Adult , Bangladesh/epidemiology , Female , Fetal Distress/diagnosis , Fetal Distress/surgery , Hospitals, Private/statistics & numerical data , Hospitals, Public/statistics & numerical data , Humans , Infant, Newborn , Infant, Postmature , Oligohydramnios/diagnosis , Oligohydramnios/surgery , Pregnancy , Retrospective Studies , Risk Factors , Socioeconomic Factors
11.
J Obstet Gynaecol Res ; 41(11): 1732-7, 2015 Nov.
Article in English | MEDLINE | ID: mdl-26369752

ABSTRACT

AIM: This study aimed to clarify the feasibility and perinatal outcomes of fetoscopic laser photocoagulation (FLP) for monochorionic twin gestation with selective intrauterine growth restriction (sIUGR) accompanied by both abnormal umbilical artery Doppler waveforms and isolated severe oligohydramnios of the sIUGR twin. METHODS: In this prospective clinical trial, which included 10 cases with absent or reversed end-diastolic flow in the umbilical artery and severe oligohydramnios of the sIUGR twin, the main outcomes investigated were the feasibility of FLP and the rate of severe FLP-related maternal complications. The survival rate and incidence of neurological abnormalities of the twins at 28 days of age were also evaluated. RESULTS: FLP was completed for all cases without major intraoperative maternal complications, although one case experienced threatened preterm labor requiring intensive treatment after the procedure. Three sIUGR and 10 larger twins were alive without neurological abnormalities at 28 days of age, while intrauterine fetal death occurred in the remaining seven sIUGR twins. CONCLUSION: FLP for monochorionic twins with sIUGR, especially when accompanied by abnormal Doppler and severe oligohydramnios of the sIUGR twin, appears to be feasible and potentially beneficial for the larger twin, as well as for some sIUGR twins.


Subject(s)
Fetal Growth Retardation/surgery , Fetoscopy/methods , Laser Coagulation/methods , Oligohydramnios/surgery , Feasibility Studies , Female , Fetal Death , Fetal Growth Retardation/mortality , Gestational Age , Humans , Infant, Newborn , Oligohydramnios/mortality , Pregnancy , Pregnancy, Twin , Prospective Studies , Survival Rate , Treatment Outcome , Twins, Monozygotic , Ultrasonography, Prenatal
12.
BMJ Case Rep ; 20152015 Jun 24.
Article in English | MEDLINE | ID: mdl-26109620

ABSTRACT

We present a case of silicosis in a 37-year-old pregnant woman, a second gravida with previous caesarean section. She was referred to our hospital at 42 weeks of gestation with breathlessness and oligohydramnios. She had worked in a glass and talc powder factory for 11 years and was diagnosed as having silicosis 2 years prior; she was on treatment. Following admission, she was evaluated for dyspnoea and underwent emergency Caesarean section for poor cervical dilation. She developed a burst abdomen on the third postoperative day with loops of gangrenous bowel protruding outside the abdomen. Emergency laparotomy with ileal resection and ileostomy was carried out. She was discharged on day 14 and is on follow-up. To the best of our knowledge, this is the first case of silicosis in pregnancy presenting with an unusual complication.


Subject(s)
Abdominal Cavity/surgery , Cesarean Section/adverse effects , Emergency Treatment/methods , Ileostomy , Ileum/pathology , Oligohydramnios/etiology , Silicosis/complications , Abdominal Cavity/pathology , Adult , Dyspnea/etiology , Female , Gangrene/etiology , Humans , Ileum/surgery , Infant, Newborn , Laparotomy , Oligohydramnios/surgery , Pregnancy , Rupture, Spontaneous/etiology , Rupture, Spontaneous/surgery , Silicosis/pathology , Silicosis/surgery , Treatment Outcome , Wound Closure Techniques
13.
J Coll Physicians Surg Pak ; 23(6): 432-3, 2013 Jun.
Article in English | MEDLINE | ID: mdl-23763807

ABSTRACT

We report a case of gastroschisis which was not diagnosed antenatally and was delivered through lower segment caesarean section due to non-reassuring cardiotocograph and small for gestational age fetus in a 21-year old mother. It was associated with oligohydramnios and partial extension of wrist joint in the neonate. After delivery, baby was referred to tertiary care for specialized care by paediatric surgeon and neonatologist where he had silo reduction and surgical repair. Postnatally, the baby is in healthy condition till now.


Subject(s)
Gastroschisis/diagnosis , Gastroschisis/surgery , Infant, Small for Gestational Age , Oligohydramnios/diagnosis , Apgar Score , Cardiotocography , Cesarean Section , Female , Gastroschisis/complications , Humans , Infant, Newborn , Male , Oligohydramnios/surgery , Pregnancy , Treatment Outcome
15.
Ultrasound Obstet Gynecol ; 37(1): 27-33, 2011 Jan.
Article in English | MEDLINE | ID: mdl-20632308

ABSTRACT

OBJECTIVE: To investigate the impact of selective fetoscopic laser photocoagulation (SFLP) on pre-existing pulmonary valve pathology in the recipient twin in twin-twin transfusion syndrome (TTTS). METHODS: We evaluated preoperative echocardiograms of all pregnancies with TTTS treated with SFLP at our institution from 2001 to 2009 (n = 76). Sixteen (21%) recipients had an abnormal pulmonary valve (stenosis/dysplasia, insufficiency or functional atresia) before SFLP. Postoperative echocardiograms and medical records from these 16 recipients were reviewed. Changes in pulmonary valve structure and function, and overall cardiac function, were noted after SFLP. RESULTS: The mean gestational age at SFLP was 21 (range, 18.7-24.3) weeks. Seven of sixteen (44%) recipients with abnormal pulmonary valve prior to SFLP survived. Six of the 16 (37.5%) recipient twins had documented absence of persistent pulmonary valve abnormalities at birth or at autopsy. Two (12.5%) of the 16 recipients (2.6% of the original cohort) had persistent pulmonary valve abnormalities at birth, requiring intervention. Systolic and diastolic function improved or normalized after SFLP in all patients undergoing longitudinal follow-up. There was a tendency for a better cardiovascular profile score (best = 10 points) at initial evaluation in pregnancies with survivors compared with those with no survivors (mean (SD): 5.6 (2.2) vs. 6.75 (1.28)), but this was not statistically significant. Severity of cardiac involvement did not predict persistence of valve pathology or survival. CONCLUSIONS: SFLP can improve flow through the pulmonary valve of the recipient twin in TTTS, probably as a consequence of improvements in right ventricular systolic and diastolic function. However, pulmonary valve pathology may persist and require postnatal intervention.


Subject(s)
Heart Valve Diseases/surgery , Laser Coagulation/methods , Pulmonary Valve/surgery , Echocardiography/methods , Female , Fetofetal Transfusion/diagnostic imaging , Fetofetal Transfusion/physiopathology , Fetofetal Transfusion/surgery , Fetoscopy , Gestational Age , Heart Valve Diseases/diagnostic imaging , Heart Valve Diseases/physiopathology , Humans , Oligohydramnios/diagnostic imaging , Oligohydramnios/physiopathology , Oligohydramnios/surgery , Pregnancy , Pulmonary Valve/diagnostic imaging , Pulmonary Valve/embryology , Retrospective Studies , Ultrasonography, Prenatal , United States
16.
J Matern Fetal Neonatal Med ; 24(3): 453-7, 2011 Mar.
Article in English | MEDLINE | ID: mdl-20608800

ABSTRACT

OBJECTIVE: The purpose of this study was to evaluate the role of transabdominal amnioinfusion in the management of oligohydramnios with the view to improving pregnancy outcome. METHODS: The study consisted of a retrospective analysis of 17 pregnant women presenting with oligohydramnios who were treated with amnioinfusion during pregnancy in a period from 2003 to 2006. RESULTS: The mean gestational age at first treatment was 24 weeks. The mean pre-procedure deepest pool of amniotic fluid was 1.8 cm and post-procedure was 3.8 cm. The mean number of infusions was 1.05. The mean first infusion to delivery interval was 31 days. Perinatal mortality was 88% and neonatal mortality was 35%, with only one baby surviving the neonatal period. There were three cases of chorioamnionitis, with one of these cases presenting with premature rupture of the membranes at the time of amnioinfusion. CONCLUSIONS: Transabdominal amnioinfusion is a useful procedure to reduce complications that result from oligohydramnios. Although the results show a high perinatal mortality, it must be borne in mind that most of these pregnancies had multiple fetal abnormalities with an already predicted poor outcome. Importantly, as this procedure increases the latency period, it may be useful in preterm pregnancies where prolonging the duration of the pregnancy may result in better perinatal outcome by improving important factors that influence survival including increased birthweight.


Subject(s)
Amniotic Fluid , Infusions, Parenteral/methods , Oligohydramnios/surgery , Abdomen/surgery , Adult , Amnion/surgery , Amniotic Fluid/physiology , Female , Fetal Mortality , Humans , Infant, Newborn , Infant, Newborn, Diseases/epidemiology , Infant, Newborn, Diseases/etiology , Infant, Newborn, Diseases/mortality , Infusions, Parenteral/mortality , Morbidity , Oligohydramnios/epidemiology , Oligohydramnios/mortality , Pregnancy , Pregnancy Outcome/epidemiology , Retrospective Studies , Treatment Outcome , Young Adult
18.
J Reprod Med ; 55(1-2): 67-70, 2010.
Article in English | MEDLINE | ID: mdl-20337211

ABSTRACT

BACKGROUND: Uterine prolapse in pregnancy is rare and can either occur during pregnancy or be present before the pregnancy. We present a case of a successful pregnancy in a patient with preexisting uterine procidentia. CASE: A 44-year-old woman with a history of complete uterine prolapse presented with an unplanned pregnancy. Upon initial presentation at 15 weeks she had uterine prolapse with cervical elongation that protruded 10 cm past the introitus. The prolapse persisted until about 30 weeks, during which it was conservatively managed with bed rest, knee-chest positions and local treatment of the desiccated cervix with emollients. The patient had an uncomplicated vaginal delivery and underwent a vaginal hysterectomy, anterior-posterior repair and a sacrospinous ligament fixation a few months later. CONCLUSION: Uterine prolapse in pregnant women with preexisting prolapse will probably resolve in the third trimester without treatment. An otherwise uncomplicated course and a vaginal delivery can be expected.


Subject(s)
Pregnancy Complications/pathology , Uterine Prolapse/pathology , Uterine Prolapse/surgery , Adult , Bed Rest , Female , Humans , Hysterectomy, Vaginal , Labor, Induced , Ligaments/surgery , Oligohydramnios/diagnosis , Oligohydramnios/surgery , Pregnancy , Pregnancy Complications/surgery , Pregnancy Outcome , Pregnancy, Unplanned , Treatment Outcome , Urinary Incontinence, Stress/etiology , Urinary Incontinence, Stress/surgery
19.
ScientificWorldJournal ; 9: 390-2, 2009 May 29.
Article in English | MEDLINE | ID: mdl-19484159

ABSTRACT

Hydronephrosis is one of the most common abnormalities detected on routine prenatal ultrasounds, being noted in up to 1% of fetuses. Rarely, severe hydronephrosis coexists with oligohydramnios, which portends a poor prognosis. We review the most recent literature on the results of prenatal intervention in this setting. Presently, the first randomized controlled trial to address whether prenatal vesicoamniotic shunting improves survival and renal function is underway, and should address the value of prenatal intervention.


Subject(s)
Ureteral Obstruction/diagnostic imaging , Ureteral Obstruction/surgery , Female , Humans , Hydronephrosis/diagnosis , Hydronephrosis/diagnostic imaging , Hydronephrosis/surgery , Oligohydramnios/diagnosis , Oligohydramnios/diagnostic imaging , Oligohydramnios/surgery , Pregnancy , Prenatal Care , Randomized Controlled Trials as Topic , Ultrasonography, Prenatal , Ureteral Obstruction/diagnosis
20.
Minerva Ginecol ; 61(2): 153-65, 2009 Apr.
Article in English | MEDLINE | ID: mdl-19255562

ABSTRACT

Twin-twin transfusion syndrome (TTTS) is a condition unique to monochorionic pregnancies, although very few case reports described the syndrome in dichorionic placentas. The aetiology of TTTS relies in the presence of at least 1 arterio-venous placental anastomosis, through which unequal blood exchange from one twin (donor) to the co-twin (recipient) occurs. The diagnosis of TTTS relies on the sonographic detection of oligohydramnios in the donor's sac and polyhydramnios in the recipient's sac in the second trimester, although signs of TTTS are present since the first trimester. Treatment options for TTTS include serial amnioreduction, septostomy, selective feticide of the apparently sick twin, and selective photocoagulation of placental vessels (SLPCV). Because of the growing evidence that SLPCV is the most efficacious therapy compared to amnioreduction with/without septostomy, the authors reviewed in details the effects of SLPCV on fetal growth and circulation. The authors further explore literature with regard to the prognostic factors. Finally, because Quintero staging system is actually under debate, they discuss the most recent findings on this topic and propose a new staging system to assess severity of TTTS at presentation (Rossi staging system). New topics for future research, which would probably further clarify the natural history of TTTS, are also proposed.


Subject(s)
Fetal Death/prevention & control , Fetofetal Transfusion/diagnostic imaging , Fetofetal Transfusion/surgery , Twins, Dizygotic , Twins, Monozygotic , Ultrasonography, Prenatal , Evidence-Based Medicine , Female , Fetofetal Transfusion/diagnosis , Fetofetal Transfusion/physiopathology , Humans , Laser Coagulation/methods , Oligohydramnios/diagnostic imaging , Oligohydramnios/surgery , Placenta/diagnostic imaging , Placenta/surgery , Polyhydramnios/diagnostic imaging , Polyhydramnios/surgery , Pregnancy , Pregnancy Outcome , Pregnancy Reduction, Multifetal , Risk Factors , Severity of Illness Index
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