[Chronorehabilitation of the patients suffering from chronic cholecystitis with concomitant gallbladder dysfunction and opisthorchiasis]. / Khronoreabilitatsiia bol'nykh khronicheskim kholetsistitom s disfunktsiei zhelchnogo puzyria i opistorkhozom.

The importance of the development of the effective rehabilitative measures for the patients suffering from chronic cholecystitis with concomitant gallbladder dysfunction and opisthorchiasis is beyond question. The adequate methods for the rehabilitation of the patients after an intensive de-worming remain to be developed. It is known that de-worming is not infrequently followed by the immediate amplification of the manifestations of the stagnation of bile in the gallbladder that become even more pronounced than before the de-worming procedure. With the purpose of improving the effectiveness of the spa and health resort-based rehabilitation and prevention of the complications, it is recommended to make use of the modern therapeutic physical factors to be prescribed taking into consideration the characteristics of the biological rhythms in the functional activity of the biliary system in the individual patients. The most effective rehabilitation methods for the treatment of the pathology in question include the application of the therapeutic physical factors known to produce the beneficial effect on the functional state of the biliary system and exert the normalizing influence on the structure of the biological rhythms of the functional activity of various organs and systems. We used a range of approaches for the treatment of 123 patients with chronic cholecystitis and concomitant gallbladder dysfunction plus opisthorchiasis including extremely high-frequency electromagnetic irradiation (EHF therapy) in the combination with the oral intake of the choleretic herbal remedies followed by the transverse galvanization of the epigastric region with due regard for the phase of the rhythm of the functional activity of the gallbladder. The results of such treatment gave evidence of the positive dynamics of all the studied indicators of the functional activity of the biliary system and the organism as a whole which suggests the highest therapeutic effect (87.9%) of the proposed treatment that was maintained during 6 to 12 months.

[The contingency of the therapeutic effectiveness with the peculiarities of the non-pharmacological treatment of the patients presenting with chronic cholecystitis]. / Sopryazhennost' terapevticheskoi effektivnosti s osobennostyami nemedikamentoznogo lecheniya bol'nykh khronicheskim kholetsistitom.

The elaboration of new technologies for the medical rehabilitation of the patients presenting with chronic cholecystitis in combination with chronic opisthorchiasis is a topical problem facing modern clinical gastroenterology. The application of up-to-date non-pharmacological therapeutic modalities, such as ultrahigh-frequency (UHF) therapy concomitantly with group chronophysiotherapy makes it possible to significantly improve the final outcome of the treatment. The results of clinical studies give evidence of the favourable influence of the combined chronorehabilitative treatment including UHF therapy on the characteristics of the functional state of the biliary-hepatic system and of the organism as a whole. The positive dynamics of these characteristics is suggestive of the high (up to 87,5%) therapeutic effectiveness of the proposed treatment. The investigations into the relationship between this effect and the peculiarities of the combined therapeutic modalities have demonstrated their correlation (χ2=104,13; p=0,0001; V-Kramer´s coefficient =0,35) and showed that the use of combined chronorehabilitation including UHF therapy based on the application of phone resonance radiation guarantees (and is a predictor of) high therapeutic effect (percent concordance =95,6%; standard coefficient=2,13; p=0,001) of the treatment of the patients with chronic cholecystitis in combination with chronic opisthorchiasis. The statistical analysis of the results of application of the modern non-pharmacological therapeutic modalities and the chronobiological approach for the purpose of the combined treatment of patients presenting with chronic cholecystitis in combination with opisthorchiasis with the use of contingency table and logit regression, allowed not only to estimate the interdependence and interrelation between the characteristics of interest but also to reveal predictors of therapeutic effectiveness. These findings are of great practical importance since they can be used for the choice of therapeutic strategies for the management of this category of patients.

[Treatment and rehabilitation of patients with chronic opisthorchiasis with skin manifestations]. / Lechenie i reabilitatsiia bol'nykh khronicheskim opistorkhozom s kozhnymi proiavleniiami.

Our studies demonstrated that chronic opisthorchosis with a skin syndrome is accompanied by a severer clinical course. The course of rehabilitation measures with the use of resort recreation (mud-bad cure) combined with traditional treatment stages makes it possible to considerably enhance the efficiency of treatment of both opisthorchosis and its skin manifestations, and should be applied more often in practice.

[The effect of thermal-vibration massage on the function of the hepatobiliary system in patients with chronic cholecystitis and opisthorchiasis]. / Vliianie termovibratsionnogo massazha na funktsional'noe sostoianie gepatobiliarnoi sistemy bol'nykh s khronicheskim kholetsistitom i opistorkhozom.

The study made by the authors has proved that thermovibration massage of infrasound frequency (10 Hz) used as an adjuvant in combined treatment of chronic cholecystitis and opisthorchiasis promotes normalization of motor-evacuatory function of the biliary system and intrahepatic hemodynamics, improves biochemical structure of the bile. This improves overall efficacy of the treatment measures.

[The role of opisthorchiasis in the development of gastroduodenal pathology in young people. Its prevention and rehabilitation]. / Rol' opistorkhoza v razvitii gastroduodenal'noi patologii u molodykh liudei. Profilaktika i reabilitatsiia.

A comprehensive examination and follow-up of 400 men aged 18 to 30 years have demonstrated that opisthorchiasis leads sooner or later to functional and morphological alterations in the gastroduodenal system. Their onset and intensity are determined by immunobiological responsiveness of the body and invasion duration. Early diagnosis, multimodality treatment including anthelminthic drugs, and rehabilitation measures enable gastroduodenal pathology to be prevented or reduced.