Rich yet undocumented ethnozoological practices of socio-culturally diverse indigenous communities of Sikkim Himalaya, India.

AIM OF THE STUDY: The indigenous people of Sikkim Himalaya possess indispensable traditional knowledge including the use of flora and fauna due to their close association with nature. The present study aims to explore the rich and undocumented ethnozoological practices of different indigenous communities of the Sikkim Himalaya. MATERIALS AND METHODS: Data was collected using semi-structured questionnaire interviews among the traditional healers and indigenous communities of Sikkim. A total of 91 respondents covering all four districts of Sikkim were interviewed from September 2017-April 2018. RESULTS: This study recorded a total of 59 species belonging to nine taxonomic groups used for traditional ethnozoological practices by the indigenous communities of Sikkim. Mammals represented 58% of the total animals followed by birds (22%). Among the total, 71% of animal species were used for zootherapy whereas 29% were used for religious customs or shamanistic practices. Almost 64% species were used for treatment of more than one disease and the chief mode of preparation was by boiling the body parts. Among different parts used in traditional medicine, meat was most preferred while horns and hairs were mostly used for religious purposes. CONCLUSION: Present findings suggest that traditional medicine including zootherapy still serves as a source of primary healthcare in rural areas of Sikkim and provides an identity to the culture of a region. We recommend documentation of more such traditional medicinal systems along with scientific validation of traditional practices with modern tools. Biodiversity Management Committees (BMCs), the legally formed bodies at local level, may be entrusted in documentation of such practices which might contribute significantly in the conservation of traditional practices and also preserves the associated traditional knowledge as per the provision of Biological Diversity Act of India.

Effects of placentophagy on maternal salivary hormones: A pilot trial, part 1.

BACKGROUND: Recent studies show that human placenta, processed and encapsulated for postpartum consumption, contains a host of trace minerals and hormones that could conceivably affect maternal physiology. Our objective was to investigate whether salivary hormone concentrations of women ingesting their own encapsulated placenta during the early postpartum differed from those of women consuming a placebo. METHODS: Randomly assigned participants (N=27) were given a supplement containing either their dehydrated and homogenized placenta (n=12), or placebo (n=15). Saliva samples were collected during late pregnancy and early postpartum. Samples of participants' processed placenta, and the encapsulated placebo, were also collected. Hormone analyses were conducted on all samples utilizing liquid chromatography-tandem mass spectrometry. RESULTS: There were no significant differences in salivary hormone concentrations between the placenta and placebo groups post-supplementation that did not exist pre-supplementation. There were, however, significant dose-response relationships between the concentration of all 15 detected hormones in the placenta capsules and corresponding salivary hormone measures in placenta group participants not seen in the placebo group. The higher salivary concentrations of these hormones in the placenta group reflects the higher concentrations of these hormones in the placenta supplements, compared to the placebo. CONCLUSIONS: Some hormones in encapsulated placenta lead to small but significant differences in hormonal profiles of women taking placenta capsules compared to those taking a placebo, although these dose-response changes were not sufficient to result in significant hormonal differences between groups. Whether modest hormonal changes due to placenta supplementation are associated with therapeutic postpartum effects, however, awaits further investigation.

Posibilidades de organoprotección en la insuficiencia cardiaca aguda / Organ protection possibilities in acute heart failure

A diferencia de la insuficiencia cardiaca (IC) crónica, el tratamiento de la IC aguda no ha cambiado en la última década. Los fármacos empleados han demostrado controlar los síntomas, pero no han conseguido una protección orgánica ni una reducción de la morbimortalidad a medio y largo plazo. Los avances en el conocimiento de la fisiopatología de la IC aguda sugieren que el tratamiento debe dirigirse no solo a corregir las alteraciones hemodinámicas y a conseguir un alivio sintomático, sino sobre todo a prevenir el daño orgánico, contrarrestando el remodelado miocárdico y las alteraciones cardiacas y extracardiacas. Las moléculas que en la fase aguda de la IC puedan ejercer acciones vasodilatadoras y antiinflamatorias —y que sean capaces de detener la muerte celular, favoreciendo los mecanismos de reparación— podrían tener un papel esencial en la protección orgánica (AU)

Unlike chronic heart failure (HF), the treatment for acute HF has not changed over the last decade. The drugs employed have shown their ability to control symptoms but have not achieved organ protection or managed to reduce medium to long-term morbidity and mortality. Advances in our understanding of the pathophysiology of acute HF suggest that treatment should be directed not only towards correcting the haemodynamic disorders and achieving symptomatic relief but also towards preventing organ damage, thereby counteracting myocardial remodelling and cardiac and extracardiac disorders. Compounds that exert vasodilatory and anti-inflammatory action in the acute phase of HF and can stop cell death, thereby boosting repair mechanisms, could have an essential role in organ protection (AU)

Consumption of the Placenta in the Postpartum Period.

Postpartum women are consuming their placentas to achieve claimed health benefits, including improved mood, energy, and lactation. Strong scientific evidence to substantiate these claims is lacking. Self-reported benefits from some women include improved mood and lactation; animal models suggest there may be an analgesic effect. Possible risks include infection, thromboembolism from estrogens in placental tissue, and accumulation of environmental toxins. Women's health care providers should be aware of this practice to help women make informed decisions.

A study on use of animals as traditional medicine by Sukuma Tribe of Busega District in North-western Tanzania.

BACKGROUND: Faunal resources have played an extensive range of roles in human life from the initial days of recorded history. In addition to their importance, animals have been acknowledged in religion, art, music and literature and several other different cultural manifestations of mankind. Human beings are acquainted with use of animals for foodstuff, cloth, medicine, etc. since ancient times. Huge work has been carried out on ethnobotany and traditional medicine. Animal and their products are also holding medicinal properties that can be exploited for the benefit of human beings like plants. In Tanzania, many tribal communities are spread all over the country and these people are still totally depended on local customary medicinal system for their health care. In the world Tanzania is gifted with wide range of floral and faunal biodiversity. The use of traditional medicine from animals by Sukuma ethnic group of Busega district is the aim of the present study. METHOD: In order to collect the information on ethnozoological use about animal and their products predominant among this tribe in Busega district, a study was carried out from August 2012, to July 2013. Data were collected through semi-structured questionnaire and open interview with 180 (118 male and 62 females) selected people. The people from whom the data were collected comprise old age community members, traditional health practicener, fishermen and cultural officers. The name of animal and other ethnozoological information were documented. Pictures and discussion were also recorded with the help of camera and voice recorder. RESULT: A total of 42 various animal species were used in nearly 30 different medicinal purposes including STD, stoppage of bleeding, reproductive disorders, asthma, weakness, tuberculosis, cough, paralysis and wound and for other religious beliefs. It has been noticed that animal used by Sukuma tribe, comprise of seventeen mammals, seven birds, four reptiles, eight arthropods and two mollusks. Some of the protected species were also used as important medicinal resources. We also found that cough, tuberculosis, asthma and other respiratory diseases are the utmost cited disease, as such, a number of traditional medicines are available for the treatment. CONCLUSIONS: The present work indicates that 42 animal species were being used to treat nearly 30 different ailments and results show that ethnozoological practices are an important alternative medicinal practice by the Sukuma tribe living in Bungesa district. The present study also indicates the very rich ethnozoological knowledge of these people in relation to traditional medicine. So there is a critical need to properly document to keep a record of the ethnozoological information. We hope that the information generated in this study will be useful for further research in the field of ethnozoology, ethnopharmacology and conservation approach.

Medicinal use of wild fauna by mestizo communities living near San Guillermo Biosphere Reserve (San Juan, Argentina).

BACKGROUND: Wild and domestic animals and their by-products are important ingredients in the preparation of curative, protective and preventive medicines. Despite the medicinal use of animals worldwide, this topic has received less attention than the use of medicinal plants. This study assessed the medicinal use of animals by mestizo communities living near San Guillermo MaB Reserve by addressing the following questions: What animal species and body parts are used? What ailments or diseases are treated with remedies from these species? To what extent do mestizo people use animals as a source of medicine? Is the use related to people's age? METHODS: We conducted semi-structured interviews with 171 inhabitants (15-93 years old) of four villages close to the Reserve: Tudcúm, Angualasto, Malimán and Colangüil. We calculated the informant consensus factor and fidelity level to test homogeneity of knowledge and to know the importance of different medicinal uses for a given species. RESULTS: The medicinal use of animals was reported by 57% of the surveyed people. Seven species were mentioned: Rhea pennata, Lama guanicoe, Puma concolor, Pseudalopex sp., Lama vicugna, Lepus europaeus and Conepatus chinga. Several body parts were used: fat, leg, bezoar-stone, stomach, feather, meat, blood, feces, wool, and liver. The fat of R. pennata was the most frequently used animal part, followed by the bezoar stone and the leg of L. guanicoe. Animals were used to treat 22 ailments, with respiratory and nervous system disorders being the most frequently treated diseases with a high degree of consensus. Old people used animals as remedies more frequently than young residents, showing some differences among villages. CONCLUSIONS: A low number of animal species was mentioned as used for medicinal purposes, which could be explained by the perception of strong control related the legislation that bans hunting and the erosion of traditional knowledge produced by mestizaje. However, the presence of a traditional medicine is deeply rooted in the community culture. Management strategy for protected areas should focus not only on the conservation and sustainability of biological resources, but also on the ancestral knowledge of local communities, such as the medicinal use of animals.

Use of medicinal fauna in Mexican traditional medicine.

ETHNOPHARMACOLOGICAL RELEVANCE: Mexico has great biodiversity of fauna. The use of fauna with medicinal properties is a common practice since pre-Hispanic times. In the last decade, there has been an interest in ethnozoological studies in Mexico. Therefore, more studies are needed in order to gather information regarding the use of fauna with medicinal properties in México. Ethnozoological studies are necessary in order to discover new medications for human health. This review presents current information in terms of ethnozoological, conservation status, trade, toxicological and pharmacological effects of fauna used for medicinal purposes in Mexican traditional medicine (MTM), based on scientific literature. Future prospects for research with medicinal fauna are discussed. MATERIALS AND METHODS: Bibliographic investigation was carried out by analyzing recognized books and peer-reviewed papers, consulting worldwide accepted scientific databases from the last five decades. Reports included in this review complied with the three criteria cited as follows: (i) used in Mexican traditional medicine for medicinal and/or magical-religious purposes, (ii) with experimental studies regarding the toxicological or medicinal effects and/or with studies exploring mechanisms of medicinal effects, and (iii) with information obtained from a clear source. RESULTS: A total of 163 animal species, belonging to 79 families and 4 taxonomic categories, used for medicinal purposes are reported in this review. Medicinal fauna used in MTM come from birds (48), fishes (3), insects (22), mammals (49) and reptiles (41). The most versatile species which had the greatest number of medicinal properties were Mephitis macroura (21 uses), Crotalus atrox (17 uses), Dasypus novemcinctus (13 uses) and Didelphis virginiana (13 uses). However, 14 of the 161 species listed in this review are classified as endangered. Animal species are mainly used for the treatment of inflammatory, respiratory and gastrointestinal diseases. Furthermore, insects and reptiles are the animal groups with more pharmacological studies. Approximately, 11% and 5% of medicinal fauna have been tested in terms of their pharmacological and toxicological effects, respectively. CONCLUSION: Despite the use of medicinal fauna in MTM, during centuries, there are a very limited number of scientific studies published on this topic. This review highlights the need to perform pharmacological, toxicological and chemical studies with medicinal fauna used in MTM.

The faunal drugstore: animal-based remedies used in traditional medicines in Latin America.

Zootherapy is the treatment of human ailments with remedies made from animals and their products. Despite its prevalence in traditional medical practices worldwide, research on this phenomenon has often been neglected in comparison to medicinal plant research. This review discusses some related aspects of the use of animal-based remedies in Latin America, identifies those species used as folk remedies, and discusses the implications of zootherapy for public health and biological conservation. The review of literature revealed that at least 584 animal species, distributed in 13 taxonomic categories, have been used in traditional medicine in region. The number of medicinal species catalogued was quite expansive and demonstrates the importance of zootherapy as an alternative mode of therapy in Latin America. Nevertheless, this number is certainly underestimated since the number of studies on the theme are very limited. Animals provide the raw materials for remedies prescribed clinically and are also used in the form of amulets and charms in magic-religious rituals and ceremonies. Zootherapeutic resources were used to treat different diseases. The medicinal fauna is largely based on wild animals, including some endangered species. Besides being influenced by cultural aspects, the relations between humans and biodiversity in the form of zootherapeutic practices are conditioned by the social and economic relations between humans themselves. Further ethnopharmacological studies are necessary to increase our understanding of the links between traditional uses of faunistic resources and conservation biology, public health policies, sustainable management of natural resources and bio-prospecting.

Zootherapeutics utilized by residents of the community Poço Dantas, Crato-CE, Brazil.

BACKGROUND: Animals have been used as a source of medicine in Brazil since ancient times, and have played a significant role in healing practices. Specifically in Northeast Brazil, zootherapy is a very common practice, and together with medicinal plants, it plays an important role as a therapeutic alternative. In the state of Ceara, no works have been carried out on rural communities with regard to use of zootherapeutics, even though the practice of zootherapy is common in this region. Therefore, the aim of this study was to analyze the use of medicinal animals in a rural community (Poco Dantas) in the municipality of Crato, Ceara, Brazil. METHODS: The field survey was carried out from October 2008 to January 2009 by conducting interviews using structured questionnaires with 72 people (33 men and 39 women), who provided information on animal species used as remedies, body parts used to prepare the remedies, and ailments for which the remedies were prescribed. We calculated the informant consensus factor (ICF) to determine the consensus over which species are effective for particular ailments, as well as the species use value (UV) to determine the extent of utilization of each species. RESULTS: A total of 29 species, distributed in 17 families were categorized as having some medicinal property. The taxa most represented were: mammals (9), insects (7), reptiles and birds (4). Progne chalybea, a species not previously recorded as being of medicinal use, was cited in the present work, where it is utilized in the treatment of alcoholism. The animals are used in the treatment of 34 diseases or symptoms, where sore throat, inflammations and cough are the ailments with the greatest number of citations. CONCLUSION: The data show that zootherapy represents an important therapeutic alternative for the inhabitants of the community. New studies on medicinal fauna should be conducted with the aim of determining the exploitation level of the species utilized, promoting sustainable development of medicinal species that are eventually threatened, and preserving and disseminating the knowledge developed by traditional individuals of the community.

Animal-based remedies as complementary medicines in Santa Cruz do Capibaribe, Brazil.

BACKGROUND: The use of animal products in healing is an ancient and widespread cross-cultural practice. In northeastern Brazil, especially in the semi-arid region, animals and plants are widely used in traditional medicine and play significant roles in healing practices. Zootherapies form an integral part of these cultures, and information about animals is passed from generation to generation through oral folklore. Nevertheless, studies on medicinal animals are still scarce in northeastern Brazil, especially when compared to those focusing on medicinal plants. This paper examines the use and commercialization of animals for medicinal purposes in Brazil's semi-arid caatinga region. METHODS: Data was obtained through field surveys conducted in the public markets in the city of Santa Cruz do Capibaribe, Pernambuco State, Brazil. We interviewed 16 merchants (9 men and 7 women) who provided information regarding folk remedies based on animal products. RESULTS: A total of 37 animal species (29 families), distributed among 7 taxonomic categories were found to be used to treat 51 different ailments. The most frequently cited treatments focused on the respiratory system, and were mainly related to problems with asthma. Zootherapeutic products are prescribed as single drugs or are mixed with other ingredients. Mixtures may include several to many more valuable medicinal animals added to other larger doses of more common medicinal animals and plants. The uses of certain medicinal animals are associated with popular local beliefs known as 'simpatias'. We identified 2 medicinal species (Struthio camelus and Nasutitermes macrocephalus) not previously documented for Brazil. The use of animals as remedies in the area surveyed is associated with socio economic and cultural factors. Some of the medicinal animal species encountered in this study are included in lists of endangered species. CONCLUSION: Our results demonstrate that a large variety of animals are used in traditional medicinal practices in Brazil's semi-arid northeastern region. In addition to the need for pharmacological investigations in order to confirm the efficiency of these folk medicines, the present study emphasizes the importance of establishing conservation priorities and sustainable production of the various medicinal animals used. The local fauna, folk culture, and monetary value of these activities are key factors influencing the use and commercialization of animal species for therapeutic purposes.

Traditional zootherapeutic studies in India: a review.

The present study aims to review the zootherapeutic practices of the different ethnic communities of India. This work is also an attempt to present a list of animals' use for medicinal purposes by different communities of India. Data were gathered from 15 published research papers of various authors on zootherapeutic studies in India from 2000 to 2007. Approximately 109 animals and their 270 uses are reported in traditional medicine in different parts of India. Of these, the highest numbers of animal species (42, 38.5%) with 50 (18.5%) uses have been reported for the treatment of Respiratory system related problems. Rheumatic and other pains are treated with 32 species (29.4%) in 34 (12.9%) uses. Gastric problems are reported to be treated with 22 (20.2%) species in 26 (9.9%) uses. The mammals constitute the highest number of animals used for medicinal purposes. 44 (40%) mammals, 24 (22%) invertebrates, 18 (17%) birds, 12 (11%) reptiles, nine (8%) fishes and two (2%) amphibians have been reported for medicinal purposes. Of the total 109 animal species reported, 76(70%) are included in IUCN red data list and 36 (33%) animal species are listed in CITES appendix I, II, and III. This work will be helpful in biodiversity conservation in India and also give a clue to investigate bio-active compound in these animal raw materials.

From cnidarians to mammals: the use of animals as remedies in fishing communities in NE Brazil.

This work documents zootherapeutic practices in Northeast Brazil. It is primarily based on field surveys carried out in fishing villages located in the states of Maranhão and Paraíba, where 60 respondents (38 men and 22 women) provided information on animal species used as medicine, body parts used to prepare the remedies and illnesses to which the remedies were prescribed. A total of 100 animal species (72 families), distributed in 12 taxonomic categories, was used as medicine. Zootherapeutic resources were used to treat 62 different diseases. The local medicinal fauna is largely based on wild animals, including some endangered species. Threatened species, such as the seahorse (Hippocampus reidi, Ginsburg, 1933) (Syngnathidae) and the green turtle (Chelonia mydas, Linnaeus, 1758) (Cheloniidae) represented important medicinal resources for the studied communities. This shows the need to integrate traditional knowledge into strategies to conserve and manage faunistic resources in Brazil.