Subject(s)
Osteoarthropathy, Primary Hypertrophic , Osteoarthropathy, Secondary Hypertrophic , Arthralgia/etiology , Humans , Hypertrophy , Male , Osteoarthropathy, Primary Hypertrophic/diagnosis , Osteoarthropathy, Secondary Hypertrophic/diagnostic imaging , Osteoarthropathy, Secondary Hypertrophic/etiology , SkinABSTRACT
Hypertrophic pulmonary osteoarthropathy( HPO) is a rare paraneoplastic manifestation of lung cancer that causes joint pain, joint swelling, and limited range of motion. Two surgical cases of lung cancer with HPO are presented. Case1:A 43-year-old female was referred to our department with a diagnosis of cStage â ¡B left hilar lung cancer. She had difficulty in walking due to arthralgia caused by HPO. Left pneumonectomy was performed and the arthralgia disappeared on the first postoperative day. The patient is being well after surgery without relapse of joint symptoms. Case2:The patient was a 65-year-old male with cStage â ¡A right lung cancer. The symptoms of HPO appeared after he was found to have lung cancer. After right upper lobectomy, the arthralgia disappeared on the first postoperative day. Currently, he is receiving adjuvant chemotherapy, without relapse of joint symptoms.
Subject(s)
Lung Neoplasms , Osteoarthropathy, Secondary Hypertrophic , Adult , Aged , Arthralgia/complications , Arthralgia/surgery , Female , Humans , Lung Neoplasms/complications , Lung Neoplasms/diagnostic imaging , Lung Neoplasms/surgery , Male , Neoplasm Recurrence, Local/surgery , Osteoarthropathy, Secondary Hypertrophic/diagnostic imaging , Osteoarthropathy, Secondary Hypertrophic/etiology , Osteoarthropathy, Secondary Hypertrophic/surgery , Pneumonectomy/adverse effectsSubject(s)
Osteoarthropathy, Secondary Hypertrophic/diagnosis , Pleural Neoplasms/diagnosis , Solitary Fibrous Tumors/diagnosis , Female , Humans , Middle Aged , Osteoarthropathy, Secondary Hypertrophic/complications , Osteoarthropathy, Secondary Hypertrophic/diagnostic imaging , Osteoarthropathy, Secondary Hypertrophic/pathology , Pleural Neoplasms/complications , Pleural Neoplasms/diagnostic imaging , Pleural Neoplasms/pathology , Radiography , Solitary Fibrous Tumors/complications , Solitary Fibrous Tumors/diagnostic imaging , Solitary Fibrous Tumors/pathology , Tomography, X-Ray ComputedSubject(s)
Hodgkin Disease/diagnostic imaging , Lung Neoplasms/diagnostic imaging , Osteoarthropathy, Secondary Hypertrophic/diagnostic imaging , Adolescent , Hodgkin Disease/complications , Humans , Lung Neoplasms/complications , Male , Osteoarthropathy, Secondary Hypertrophic/etiology , Radiography, ThoracicABSTRACT
CASE PRESENTATION: A 49-year-old man was sent by his primary care physician to the rheumatology clinic with complaints of several months of bilateral lower extremity swelling. The swelling migrated from both ankles up to his knees. Presenting symptoms consisted of bilateral knee pain as well as bilateral wrist and hand pain with swelling. Pulmonary symptoms consisted of a nagging productive cough of several months. He also complained of significant weight loss: 50 pounds over 12 months. He was a never smoker. The examination was notable for bilateral knee effusions. Radiographs of his wrists, hands, and knee were obtained, along with a chest radiograph. He was then referred to a pulmonologist for further workup.
Subject(s)
Hemangioendothelioma, Epithelioid/complications , Lung Neoplasms/complications , Osteoarthropathy, Secondary Hypertrophic/etiology , Ankle Joint , Arthralgia/etiology , Cough/etiology , Hand Joints , Hemangioendothelioma, Epithelioid/diagnostic imaging , Hemangioendothelioma, Epithelioid/pathology , Hemangioendothelioma, Epithelioid/surgery , Humans , Immunohistochemistry , Knee Joint/diagnostic imaging , Lung Neoplasms/diagnostic imaging , Lung Neoplasms/pathology , Lung Neoplasms/surgery , Male , Middle Aged , Osteoarthropathy, Secondary Hypertrophic/diagnostic imaging , Tomography, X-Ray Computed , Weight Loss , Wrist JointSubject(s)
Carcinoma, Squamous Cell , Hand/diagnostic imaging , Lung Neoplasms , Lung/diagnostic imaging , Osteoarthropathy, Secondary Hypertrophic , Tomography, X-Ray Computed/methods , Anti-Inflammatory Agents/therapeutic use , Carcinoma, Squamous Cell/pathology , Carcinoma, Squamous Cell/physiopathology , Carcinoma, Squamous Cell/surgery , Child , Diagnosis, Differential , Female , Humans , Lung Neoplasms/pathology , Lung Neoplasms/physiopathology , Lung Neoplasms/surgery , Neoplasm Staging , Osteoarthropathy, Secondary Hypertrophic/diagnostic imaging , Osteoarthropathy, Secondary Hypertrophic/etiology , Osteoarthropathy, Secondary Hypertrophic/physiopathology , Pneumonectomy/methods , Treatment OutcomeABSTRACT
Primary hepatic angiosarcoma was diagnosed in a 59-year-old woman who presented an arthralgia of limbs and dry cough for 6 weeks. Physical examination revealed digital clubbing. A Tc-MDP bone scintigraphy showed diffusely increased uptake along the cortical margins of long bones, suggesting hypertrophic osteoarthropathy.
Subject(s)
Hemangiosarcoma/diagnostic imaging , Liver Neoplasms/diagnostic imaging , Osteoarthropathy, Secondary Hypertrophic/diagnostic imaging , Female , Hemangiosarcoma/complications , Humans , Liver Neoplasms/complications , Middle Aged , Osteoarthropathy, Secondary Hypertrophic/complications , Positron Emission Tomography Computed Tomography , Radiopharmaceuticals , Technetium Tc 99m MedronateABSTRACT
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