ABSTRACT
A preterm (30+2 week) neonate with below-knee amputation (right lower limb), constriction rings and syndactyly, subsequent to amniotic band sequence, developed pus discharge from the right tibial stump. The neonate did not have clinical features of systemic sepsis. Blood culture was sterile. The pus culture, however, grew methicillin-resistant coagulase-negative Staphylococcus and bone scan was suggestive of osteomyelitis of right proximal tibial stump. Osteomyelitis was likely caused by the contiguous spread of infection from the exposed stump. Neonate was treated with intravenous antibiotics for 4 weeks and discharged on oral feeds.
Subject(s)
Amniotic Band Syndrome/physiopathology , Amputation Stumps/pathology , Amputation, Surgical , Lower Extremity/pathology , Methicillin-Resistant Staphylococcus aureus/pathogenicity , Osteomyelitis/pathology , Staphylococcal Infections/physiopathology , Amniotic Band Syndrome/complications , Amniotic Band Syndrome/embryology , Amputation Stumps/blood supply , Amputation Stumps/microbiology , Anti-Bacterial Agents/therapeutic use , Humans , Infant, Newborn , Lower Extremity/blood supply , Lower Extremity/embryology , Lower Extremity/microbiology , Male , Osteomyelitis/drug therapy , Osteomyelitis/embryology , Staphylococcal Infections/drug therapy , Treatment OutcomeABSTRACT
The clinical course of fetal osteomyelitis was analyzed in 5 newborns. All of them had poorly manifested course of osteomyelitis, the absence of abscess formation and low information on traditional laboratory tests. The prenatal aspects of the intrauterine infection of the fetus responsible for the development of osteomyelitis, methods of diagnosing and treatment of fetal osteomyelitis were described. Long-tern results of treatment of children with this pathology are studied. The "beam" symptom characteristic of newborn osteomyelitis is also described.
