ABSTRACT
Choroid plexus papillomas (CPP) are rare tumours and spinal metastases of CPP are even less common. We report a 50-year-old woman with spinal drop metastases at Th9 and S1-2 6 years after total resection of a posterior fossa CPP. The metastasis at S1-2 was resected and histological examination showed transformation to an atypical CPP. Atypical transformation in a metastasis years after resection of a benign posterior fossa CPP has been described once. We would like to advocate craniospinal MRI at the time of initial diagnosis as well as periodic follow-up after total and subtotal resection of a posterior fossa CPP in adults at least once in 1 or 2 years, depending on the histological grading of the primary CPP. In our case report, this could have resulted in earlier diagnosis of the locoregional recurrence or of the spinal drop metastasis.
Subject(s)
Neoplasm Recurrence, Local/radiotherapy , Papilloma, Choroid Plexus/pathology , Sacrum/pathology , Spinal Neoplasms/pathology , Craniotomy , Female , Humans , Magnetic Resonance Imaging , Middle Aged , Neoplasm Recurrence, Local/diagnosis , Papilloma, Choroid Plexus/secondary , Papilloma, Choroid Plexus/therapy , Spinal Neoplasms/radiotherapy , Spinal Neoplasms/secondarySubject(s)
Cerebellopontine Angle/pathology , Neurofibromatosis 2/diagnosis , Papilloma, Choroid Plexus/diagnosis , Adult , Cerebellopontine Angle/surgery , Diagnosis, Differential , Humans , Male , Neurofibromatosis 2/surgery , Papilloma, Choroid Plexus/secondary , Papilloma, Choroid Plexus/surgeryABSTRACT
Choroid plexus papillomas are rare tumours, which occasionally spread both intracranially and down the spinal canal. Spinal metastasis has been reported infrequently and only once many years since the initial diagnosis. This is the first reported case of late recurrence, metastasis and transformation of a benign to an atypical lesion.
Subject(s)
Fourth Ventricle/pathology , Papilloma, Choroid Plexus/secondary , Spinal Cord Neoplasms/secondary , Aged , Humans , Male , Papilloma, Choroid Plexus/surgery , Spinal Cord Neoplasms/surgery , Treatment OutcomeABSTRACT
A rare case of choroid plexus papilloma (CPP) with spinal drop metastasis is presented. A 51-year-old woman was operated on for a tumor of the fourth ventricle with histopathological diagnosis of CPP. Seven years later, she was re-admitted with low back pain. MRI showed multilobulated tumor at the lumbosacral subarachnoidal space with histopathological diagnosis of CPP. Thus, CPP can spread via the cerebrospinal fluid pathways and cause drop metastasis.
Subject(s)
Choroid Plexus Neoplasms/pathology , Glioma/pathology , Papilloma, Choroid Plexus/secondary , Papilloma/pathology , Spinal Cord Neoplasms/secondary , Choroid Plexus Neoplasms/surgery , Female , Fourth Ventricle/pathology , Glioma/surgery , Humans , Laminectomy , Lumbar Vertebrae , Middle Aged , Papilloma/surgery , Papilloma, Choroid Plexus/surgery , Spinal Cord Neoplasms/surgery , Treatment OutcomeABSTRACT
Choroid plexus papilloma is a benign central nervous system tumor that occasionally spreads along the subarachnoid space. The authors report the case of a 49-year-old man who presented with back pain 19 years after resection of a posterior fossa choroid plexus papilloma. Magnetic resonance imaging revealed multiple spinal lesions without any residual or recurrent intracranial tumor. All spinal lesions were resected and histologically diagnosed as atypical choroid plexus papilloma. The authors suggest that patients in whom choroid plexus papilloma is diagnosed should undergo total neuraxis imaging at the time of initial diagnosis as well as periodic follow-up examinations after resection to rule out drop metastases.
