ABSTRACT
Dynamics of the cerebrospinal fluid were measured pre- and postoperatively in a patient with a choroid plexus papilloma associated with hydrocephalus. The production rate was 0.35 ml/min, absorption 0.0057 ml/min H2O, and the critical opening pressure 196 mm H2O. Following removal of the tumor, these values were 0.32 ml/min, 0.0053 ml/min/mm H2O, and 105 mm H2O, respectively. It was concluded that no over-production of cerebrospinal fluid was present in this case. The hydrocephalus was due solely to obstruction of the fourth ventricle.
Subject(s)
Brain Neoplasms/complications , Choroid Plexus/surgery , Papilloma/complications , Adult , Brain Neoplasms/cerebrospinal fluid , Choroid Plexus/physiopathology , Humans , Hydrocephalus/cerebrospinal fluid , Hydrocephalus/etiology , Male , Papilloma/cerebrospinal fluidABSTRACT
A choroid plexus papilloma was found in the right lateral ventricle of a five-month-old boy. Though it was associated with an important communicating hydrocephalus, it was seen at operation to be freely mobile and did not directly obstruct the flow of the cerebrospinal fluid. Computerized axial tomography was the most helpful para-clinical investigation for diagnostic purposes, and for follow-up study. Tumor removal alone was sufficient to cure the hydrocephalus, and no shunt was necessary. We feel that this case demonstrates that hyperproduction of CSF is sufficient alone to cause communicating hydrocephalus in patients with choroid plexus papilloma of the lateral ventricle.
Subject(s)
Cerebral Ventricle Neoplasms/cerebrospinal fluid , Choroid Plexus , Hydrocephalus/etiology , Papilloma/cerebrospinal fluid , Cerebral Ventricle Neoplasms/pathology , Cerebral Ventricle Neoplasms/surgery , Humans , Infant , Male , Papilloma/pathology , Papilloma/surgery , Tomography, X-Ray ComputedABSTRACT
Utilizing a ventricular perfusion technique, the rate of CSF formation was determined in a 2-year-old child before and after removal of a 74 g choroid plexus papilloma from the left lateral ventricle. Preoperatively, the CSF formation rate was 1.05 +/- SD 0.01 ml/min (1,656 ml/day). Postoperatively, the CSF formation rate was reduced fivefold to 0.20 +/- SD 0.01 ml/min (288 ml/day). Whereas these data are regarded as conclusive evidence of CSF overproduction by a choroid plexus papilloma, the pathogenesis of generalized ventricular enlargement in this case was due to part to obstruction of the subarachnoid pathways.
