1.
Life Sci
; 41(11): 1355-9, 1987 Sep 14.
Article
in English
| MEDLINE
| ID: mdl-3626760
ABSTRACT
The effect of maternal glucocorticoid depletion upon the fetal development of the organ of Zuckerkandl (OZ) in rats was determined. Maternal hypophysectomy at 13d8h gestation resulted in a fifty percent decrease in plasma corticosterone levels at 18d8h when compared to both sham operated and unoperated controls. No differences in the volume of the OZ among the three groups of animals were found. The chromaffinity of the OZ was decreased in the hypophysectomized and sham operated groups suggesting a stress-induced depletion of catecholamine stores. The data suggests that the OZ participates in fetal sympathoadrenal activity and that its development is independent of maternal corticosterone titers.
Subject(s)
Chromaffin System/embryology , Para-Aortic Bodies/embryology , Animals , Corticosterone/blood , Female , Hypophysectomy , Maternal-Fetal Exchange , Pituitary-Adrenal System/embryology , Pregnancy , Rats
2.
Dev Biol
; 89(2): 299-308, 1982 Feb.
Article
in English
| MEDLINE
| ID: mdl-7035256