ABSTRACT
Paragonimiasis is a parasitic disease caused by the lung fluke, Paragonimus spp. Lung flukes may be found in various organs, such as the brain, peritoneum, subcutaneous tissues, and retroperitoneum, other than the lungs. Abdominal paragonimiasis raises a considerable diagnostic challenge to clinicians, because it is uncommon and may be confused with other abdominopelvic inflammatory diseases, particularly peritoneal tuberculosis, and peritoneal carcinomatosis. Also, subcutaneous paragonimiasis does not easily bring up clinical suspicion, due to its rarity. We herein report 2 cases of abdominal paragonimiasis and 1 case of subcutaneous paragonimiasis in Korea.
Subject(s)
Abdominal Cavity/parasitology , Paragonimiasis/pathology , Paragonimus/isolation & purification , Subcutaneous Tissue/parasitology , Animals , Biopsy, Fine-Needle , Diagnosis, Differential , Female , Humans , Male , Middle Aged , Paragonimiasis/diagnostic imaging , Paragonimiasis/parasitology , Paragonimus/cytology , Radiography , Republic of KoreaABSTRACT
Paragonimiasis is a parasitic disease caused by the lung fluke, Paragonimus spp. Lung flukes may be found in various organs, such as the brain, peritoneum, subcutaneous tissues, and retroperitoneum, other than the lungs. Abdominal paragonimiasis raises a considerable diagnostic challenge to clinicians, because it is uncommon and may be confused with other abdominopelvic inflammatory diseases, particularly peritoneal tuberculosis, and peritoneal carcinomatosis. Also, subcutaneous paragonimiasis does not easily bring up clinical suspicion, due to its rarity. We herein report 2 cases of abdominal paragonimiasis and 1 case of subcutaneous paragonimiasis in Korea.
Subject(s)
Animals , Female , Humans , Male , Middle Aged , Abdominal Cavity/parasitology , Biopsy, Fine-Needle , Diagnosis, Differential , Paragonimiasis/parasitology , Paragonimus/cytology , Republic of Korea , Subcutaneous Tissue/parasitologyABSTRACT
We report a case of paragonimiasis involving a 12-year-old Latin American boy. The diagnosis was made by fine-needle aspiration biopsy of a pulmonary nodule. Identification of the species by morphometric analysis of the eggs indicated that the infection was caused by Paragonimus mexicanus.
Subject(s)
Biopsy, Needle/methods , Lung Diseases, Parasitic/diagnosis , Paragonimiasis/diagnosis , Paragonimus/isolation & purification , Animals , Child , Humans , Lung Diseases, Parasitic/parasitology , Male , Ovum/cytology , Paragonimiasis/parasitology , Paragonimus/cytologyABSTRACT
Morphology and respiratory function were studied in situ and in the isolated mitochondria of Paragonimus ohirai. Two types of parenchymal cells (i.e., Pc1 and Pc2 cells), whose mitochondria differ in terms of morphology and staining for cytochrome c oxidase activity, were found in fluke tissues. Enzymatic and spectrophotometric analyses of the isolated mitochondria showed that fluke mitochondria possess both aerobic and anaerobic respiratory chains. These results suggest that there are two mitochondrial populations in fluke parenchymal cells, one possessing an aerobic respiratory chain and the other an anaerobic respiratory chain.
Subject(s)
Mitochondria/ultrastructure , Paragonimus/cytology , Animals , Cytochromes/metabolism , Kinetics , Microscopy, Electron , Mitochondria/metabolism , Oxygen Consumption , Paragonimus/metabolism , Paragonimus/ultrastructure , Rats , Rats, Sprague-Dawley , Submitochondrial Particles/metabolism , ThermodynamicsABSTRACT
We report a case of paragonimiasis in a Nigerian woman evaluated for symptoms of chronic respiratory disease five years after chemotherapy for primary lymphoma of the breast. Fine needle aspiration of one of two fibrocavitary pulmonary lesions yielded thick, brown material in which ova diagnostic of Paragonimus westermani were identified cytologically. This disease is unusual in natives of North America but is seen in travelers and immigrants from Asia, Africa, and South and Central America, where it is endemic. The infection can be fatal, especially if it involves the central nervous system. The clinical differential is broad, but an accurate diagnosis may be made by fine needle aspiration, thus allowing proper treatment.
Subject(s)
Lung Diseases, Parasitic/parasitology , Paragonimiasis/parasitology , Paragonimus/isolation & purification , Adult , Animals , Biopsy, Needle , Female , Humans , Lung Diseases, Parasitic/pathology , Ovum/pathology , Paragonimiasis/pathology , Paragonimus/cytologyABSTRACT
In this paper taxonomic study on paragonimus including their metacercariae obtained from the crabs collected from Sorsogon, Luzon, Philippines and adult worms and ova obtained through animal feeding, with light microscopy and scanning electron microscopy revealed that there may exist two or more species of lung flukes in Philippines. The occurrence of Semisulcospira libertina in addition to Antemelania dactylus (Lea) as an additional snail host is mentioned for the first time. The chromosome Karyotyping of the adult worms revealed that they belong to the diploid pattern. Electronic scanning showed that the cuticular spines of the Paragonimus from Sorsogon look like "pineapple ears" both in distribution and in appearance, a new finding that has not been recorded before. In the lungs of a white rat killed 290 days after infection, two adult worms were obtained within the solitary cyst. These 2 adult worms measured 4.5 x 2.5 mm and 4.5 x 3.0 mm respectively. Their unusually small size and somewhat round shape suggest that they may be of a different species from those hitherto reported in the Philippines. Clearcut evidence is presented for the first time, demonstrating the occurrence of the phenomenon of cross fertilization (allogamy) of lung flukes.
