ABSTRACT
BACKGROUND: Inflammatory myofibroblastic tumor (IMT) is a mesenchymal tumor mainly found in lung or retroperitoneum and rarely affects head and neck region. Extensive English literature search reveals that less than fifty cases of head and neck IMT have been reported so far, maxillary sinus being fewer. CASE PRESENTATION: We present a case of IMT involving maxillary sinus in a 48-year-old gentleman who attained complete clinico-radiologic response after treatment with radiotherapy (RT) and concurrent oral prednisolone. CONCLUSIONS: This is the first report where such magnificent response was attained in primary setting treated with RT and steroids as opposed to surgery which used to be considered as standard of care till now.
Subject(s)
Granuloma, Plasma Cell/therapy , Maxillary Sinus/pathology , Paranasal Sinus Diseases/therapy , Prednisolone/therapeutic use , Combined Modality Therapy , Granuloma, Plasma Cell/diagnostic imaging , Granuloma, Plasma Cell/radiotherapy , Humans , Male , Middle Aged , Paranasal Sinus Diseases/diagnostic imaging , Paranasal Sinus Diseases/radiotherapySubject(s)
Histiocytosis, Sinus/diagnostic imaging , Maxillary Diseases/diagnostic imaging , Maxillary Sinus/pathology , Paranasal Sinus Diseases/diagnostic imaging , Diagnosis, Differential , Female , Histiocytosis, Langerhans-Cell/diagnosis , Histiocytosis, Sinus/pathology , Histiocytosis, Sinus/radiotherapy , Histiocytosis, Sinus/surgery , Humans , Maxillary Diseases/pathology , Maxillary Diseases/radiotherapy , Maxillary Diseases/surgery , Maxillary Sinus/surgery , Middle Aged , Molar/physiopathology , Paranasal Sinus Diseases/pathology , Paranasal Sinus Diseases/radiotherapy , Paranasal Sinus Diseases/surgery , Radiography , Tooth MobilityABSTRACT
The authors present a case of synchronous manifestation of a myeloproliferative--extramedullary plasmocytoma--and a chronic inflammatory disease of the nose and the paranasal sinuses. They emphasise the importance of imaging techniques and immunohistochemistry in the differential diagnosis. They discuss on the basis of published articles the new classification, clinical manifestations, diagnostic and therapeutical approaches of this tumour belonging to the group of monoclonal gammopathies, which originates from an abnormal proliferation of mature B-lymphocytes, and is a rarity in the literature even nowadays.
Subject(s)
Myeloproliferative Disorders/diagnosis , Nose Diseases/diagnosis , Paranasal Sinus Diseases/diagnosis , Diagnosis, Differential , Female , Humans , Immunohistochemistry , Inflammation/pathology , Magnetic Resonance Imaging , Middle Aged , Myeloproliferative Disorders/radiotherapy , Nose Diseases/radiotherapy , Nose Neoplasms/diagnosis , Paranasal Sinus Diseases/radiotherapy , Paranasal Sinus Neoplasms/diagnosis , Plasmacytoma/diagnosis , Tomography, X-Ray ComputedABSTRACT
OBJECTIVE: To observe therapeutic effect of microwave eliminating the remnant lesion located at walls of maxillary sinus after endoscopic maxillary sinus surgery and the effect of postoperative. METHOD: Twenty-six cases (37 sites) were treated with microwave coagulating through enlarged ostium completely by means of 70 degrees endoscopy-guided. RESULT: The remnant lesion located at walls of maxillary sinus of 23 cases (33 sites) were eliminated without any complication and the effective eliminating rate was 89.2% (33/37). The infected local secretion of maxillary sinus of 17 cases (22 sites) were disappeared. CONCLUSION: The therapy of microwave by means of nasal endoscopy-guided can get rid of the lesion which is located at walls of the maxillary sinus to avoid the trauma caused by Caldwell-Luc operation, etc. It can improve the effect of the endoscopic sinus surgery.
Subject(s)
Cysts/radiotherapy , Endoscopy , Maxillary Sinus/surgery , Microwaves/therapeutic use , Paranasal Sinus Diseases/radiotherapy , Polyps/radiotherapy , Adolescent , Adult , Combined Modality Therapy , Cysts/surgery , Female , Follow-Up Studies , Humans , Male , Maxillary Sinus Neoplasms/radiotherapy , Maxillary Sinus Neoplasms/surgery , Nasal Polyps/radiotherapy , Nasal Polyps/surgery , Paranasal Sinus Diseases/surgery , Polyps/surgery , Postoperative PeriodABSTRACT
A case of pseudotumour of the paranasal sinuses occurring in a patient with haemophilia A is reported. There was a favourable response to combined treatment with radiation therapy and factor VIII replacement.
