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1.
Hosp. domic ; 4(3): 117-131, jul.-sept. 2020. tab, graf
Article in Spanish | IBECS | ID: ibc-200925

ABSTRACT

OBJETIVO: Revisar la documentación científica relacionada con la calidad de vida de las personas adultas con nutrición parenteral ingresadas en hospitalización domiciliaria. MÉTODO: Revisión crítica y sistemática. Los datos se obtuvieron de la consulta a las siguientes bases de datos bibliográficas: MEDLINE (vía PubMed), Cochrane Library, Embase, Scopus y Web of Science. Los términos utilizados, como descriptores y como texto en los campos de registro del título y el resumen, fueron "Home Care Services", "Parenteral Nutrition" y "Quality of Life", utilizando los filtros «Humans», «Adult: 19+ years» y «Clinical Trial». Fecha de la búsqueda febrero de 2020. La calidad documental de los artículos se evaluó mediante el cuestionario CONSORT. RESULTADOS: De las 379 referencias recuperadas, tras depurar las repeticiones y aplicar los criterios de inclusión y exclusión, se seleccionaron 7 ensayos clínicos. En 3 (43%) de los ensayos revisados se observó una mejora en relación a la calidad de vida. Las puntuaciones obtenidas mediante el cuestionario CONSORT, oscilaron entre 12,5 y 20,5 sobre una puntuación máxima de 24. CONCLUSIONES: El incremento de la calidad de vida de los enfermos con NPD está directamente relacionado con la del estado y soporte nutricional de los mismos. Se observó una mejor calidad de vida en los pacientes con bomba portátil y en los que se administró teduglutida. El adecuado manejo del catéter y la consecuente disminución de las infecciones también contribuyó a la mejora de la calidad de vida de las personas con NPD


OBJECTIVE: To review the scientific documentation related to the quality of life of adult people with parenteral nutrition admitted to home hospitalization. METHOD: Critical and systematic review. The data were obtained from the consultation of the following bibliographic databases: MEDLINE (via PubMed), Cochrane Library, Embase, Scopus y Web of Science. Terms used as descriptors and as text in the title and summary record fields were: "Home Care Services", "Parenteral Nutrition" and "Quality of Life", using the filters «Humans», «Adult: 19+ years» y «Clinical Trial». Search date February 2020. The documental quality of the articles was evaluated by using the CONSORT questionnaire. RESULTS: From 379 recovered references, after refining the repetitions and applying the inclusion and exclusion criteria, 7 clinical trials were selected. In 3 (43%) of the revised trials it was observed an improvement in relation to the quality of life. The scores obtained by the CONSORT questionnaire were from 12.5 to 20.5 with a maximum score of 24. CONCLUSIONS: The parenteral support of patients with home parenteral nutrition (HPN) was directly related to the nutritional status, and it corresponded with an increase in quality of life. An improvement of quality of life was proved in patients that used portable pump and it was likewise proved that the use of teduglutide was beneficial for the quality of life. The correct handle of the catheter and the reduction of infections were also connected with the enhancement of the quality of life of people with HPN


Subject(s)
Humans , Home Care Services, Hospital-Based/trends , Parenteral Nutrition, Home Total/methods , Parenteral Nutrition/statistics & numerical data , Quality of Life , Sickness Impact Profile , Nutrition Assessment , Nutritional Status
2.
Nutrients ; 12(5)2020 Apr 28.
Article in English | MEDLINE | ID: mdl-32353942

ABSTRACT

BACKGROUND: The effect of 1-3 months of preoperative exclusive total parental nutrition (TPN) in active Crohn's disease (CD) patients is not well established. We investigated the efficacy of exclusive TPN in active CD patients. METHODS: In a retrospective multi-visit study with data according to our standard care therapy, we assessed clinical and laboratory remission to refractory CD with exclusive preoperative TPN. Inclusion required exclusive preoperative home TPN without additional oral intake for 1-3 months prior to planning surgery. RESULTS: Twenty preoperative CD patients (65% male; 35% female) were on exclusive TPN. The mean age of the cohort was 30.8 ± 11.6 years. Mean duration of preoperative TPN treatment was 73 days (range: 24-142 days). Most patients had terminal ileal (35%) or ileocolonic CD (30%), and with stricturing (B2) phenotype. All 20 patients had significant clinical improvement in all disease activity indices at the end of preoperative TPN (baseline vs. post TPN): HBI 14.5 vs. 4.0 (p = 0.001); BMI 19.2 vs. 19.7 kg/m2 (p = 0.017); CRP 57.2 vs. 10.3 mg/L (p = 0.001); Fecal calprotectin (FC) 672 vs. 200 (µg/g); albumin 2.7 vs. 3.6 g/dL (p = 0.001). Two patients (10%) no longer required surgery after completion of exclusive TPN. CONCLUSION: Exclusive preoperative TPN was found to provide significant improvement in nutritional status, and clinical and laboratory remission in severe active Crohn's patients.


Subject(s)
Crohn Disease/rehabilitation , Crohn Disease/surgery , Nutritional Physiological Phenomena/physiology , Nutritional Status , Parenteral Nutrition, Home Total/methods , Preoperative Care/methods , Remission Induction/methods , Adult , Female , Humans , Male , Pilot Projects , Preoperative Period , Retrospective Studies , Severity of Illness Index , Time Factors , Treatment Outcome , Young Adult
3.
Medicine (Baltimore) ; 98(21): e15747, 2019 May.
Article in English | MEDLINE | ID: mdl-31124957

ABSTRACT

In chronic kidney disease (CKD), the design of the parenteral nutrition (PN) regimen becomes more challenging where only individualized PN is appropriate, coupled with the increased risk of unintended interactions with diuretic therapy. In an effort to ensure safe therapy in the home, we assessed the physical stability of bespoke PN formulations intended for use in CKD in the simultaneous presence of Y-site compatibility of furosemide and torasemide. The patient's daily needs were determined based on both metabolic demands as well as the demand for fluids.Complete admixtures were subjected to physical stability analysis consisting of visual inspection, a validated light microscope method, pH measurement, zeta potential measurement, and characterization of oily globule size distribution. Y-site compatibility of furosemide and torasemide with the formulated admixtures was also performed.The total parenteral admixture was stable over 7 days at +4°C and 24 h at +25°C and compatible via the Y-line together with furosemide and torasemide over 12 h at +25°C.The stability assessment guarantees the safety and efficiency of home PN with loop diuretics therapy in CKD patients. This means that these patients do not need long hospitalization and they can be safely treated at home. Furthermore, this study proved that torasemide is the same safety diuretic as furosemide, which has a great impact on clinical practice.


Subject(s)
Parenteral Nutrition, Home Total/methods , Renal Insufficiency, Chronic/therapy , Sodium Potassium Chloride Symporter Inhibitors/administration & dosage , Sodium Potassium Chloride Symporter Inhibitors/chemistry , Administration, Intravenous , Drug Incompatibility , Furosemide/administration & dosage , Furosemide/chemistry , Humans , Hydrogen-Ion Concentration , Particle Size , Torsemide/administration & dosage , Torsemide/chemistry
4.
J BUON ; 23(1): 244-247, 2018.
Article in English | MEDLINE | ID: mdl-29552791

ABSTRACT

PURPOSE: Home parenteral nutrition (HPN) has been proposed as the treatment of choice in patients suffering from intestinal failure (IF) and has been claimed to improve survival and quality of life either in patients with benign disorders or even in those with malignancies. The purpose of the present analysis was to report characteristics and outcomes of adult patients with IF receiving HPN in Greece. METHODS: Patients that received HPN between 2011 and 2017 were included in this retrospective analysis. Characteristics of the included patients, cause of HPN, duration of HPN, route of HPN administration, complications as well as survival rates were recorded. RESULTS: A total of 189 patients were included in the present analysis. Of these, 163 (86.3%) suffered from cancer while 26 (13.7%) received HPN due to non-malignant diseases. The reported mortality was 74.6% while overall severe complications rate was 77%. CONCLUSIONS: According to the findings of our study, HPN seems to have beneficial effect but it should be considered with caution by the physicians who should take into account the indications of each patient to receive parenteral nutrition, the underlying disease and prognosis and the access of each patient to home care services.


Subject(s)
Neoplasms/complications , Nutrition Disorders/therapy , Parenteral Nutrition, Home Total/methods , Adolescent , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Prognosis , Quality of Life , Retrospective Studies , Survival Rate , Young Adult
5.
Endocrinol. diabetes nutr. (Ed. impr.) ; 65(supl.1): 19-23, mar. 2018. tab, ilus
Article in Spanish | IBECS | ID: ibc-172973

ABSTRACT

La desnutrición es un problema médico frecuente de los pacientes oncológicos que impacta de forma negativa en la calidad de vida. El objetivo de este trabajo es analizar y dar respuesta a diferentes cuestiones relacionadas con el manejo nutricional de un paciente oncológico en la práctica clínica. Un grupo multidisciplinar de expertos en Oncología Médica, Endocrinología y Nutrición y Farmacia elaboró una lista de temas relacionados con el estado nutricional del paciente oncológico agrupados en 3 bloques: soporte nutricional, nutrición parenteral (NP) y NP domiciliaria (NPD). Se realizó una revisión de la literatura que incluyó artículos publicados en español, inglés y francés hasta abril de 2017. Este consenso destaca diferentes elementos clave que ayudarán a los médicos a normalizar el manejo del estado nutricional del paciente oncológico en la práctica clínica, estableciendo pautas comunes de indicación, monitorización, requerimientos nutricionales y vías de acceso a la NP


Malnutrition is a common medical problem in cancer patients with a negative impact on quality of life. The aim of this study was to address different issues related to nutritional management of cancer patients in clinical practice. A multidisciplinary group of experts in Medical Oncology, Pharmacy, and Endocrinology and Nutrition prepared a list of topics related to the nutritional status of cancer patients and grouped them into three blocks: nutritional support, parenteral nutrition (PN), and home PN (HPN). A literature review was made of articles published in Spanish, English and French until April 2017. This consensus emphasizes several key elements that help physicians standardize management of the nutritional status of cancer patients in clinical practice, and establishes common guidelines for indication, monitoring, nutritional requirements, and access routes to PN


Subject(s)
Humans , Nutritional Support/methods , Parenteral Nutrition/methods , Neoplasms/diet therapy , Malnutrition/diet therapy , Quality of Life , Practice Patterns, Physicians' , Parenteral Nutrition, Home Total/methods , Enteral Nutrition/methods , Nutrition Therapy/methods
6.
Br J Community Nurs ; Suppl Nutrition: S24, S26-7, 2015.
Article in English | MEDLINE | ID: mdl-26087204

ABSTRACT

This article explores the complexities of home parenteral nutrition (HPN) and how it has developed as a home therapy. It examines the various indications and treatment options, discussing access and the associated complications. The relationship between the multiprofessional team is paramount to the success of the therapy. Working in partnership with home-care providers is also discussed. It gives an overview of patients receiving parenteral nutrition at home and the impact it has on their lives.


Subject(s)
Intestinal Diseases/diet therapy , Intestinal Diseases/nursing , Parenteral Nutrition, Home Total/methods , Parenteral Nutrition, Home Total/nursing , Patient Care Team/organization & administration , Humans , Interprofessional Relations
7.
J Pediatr Gastroenterol Nutr ; 59(2): 177-81, 2014 Aug.
Article in English | MEDLINE | ID: mdl-24796804

ABSTRACT

Patients receiving home parenteral nutrition (HPN) are at particularly high risk of meticillin-sensitive Staphylococcus aureus (MSSA) catheter-related bloodstream infections (CRBSI). We developed a multidisciplinary enhanced care pathway encompassing a number of minimal cost interventions involving line/exit site care, training for staff and parents, multidisciplinary discharge planning, and monitoring compliance. Implementation reduced the mean rates of MSSA CRBSI (from 0.93, 95% CI 0.25-1.61, to 0.23, 95% CI -0.06 to 0.52, per 1000 parenteral nutrition [PN] days) and all-cause CRBSI (from 1.98, 95% CI 0.77-3.19, to 0.45, 95% CI 0.10-0.80, per 1000 PN days). A similar approach could be applied to preventing health care-associated infections in other complex, vulnerable patient groups.


Subject(s)
Bacteremia/prevention & control , Catheter-Related Infections/prevention & control , Catheterization, Central Venous/adverse effects , Catheters, Indwelling/adverse effects , Parenteral Nutrition, Home Total/adverse effects , Parenteral Nutrition, Home/adverse effects , Staphylococcus aureus , Adolescent , Bacteremia/etiology , Bacteremia/microbiology , Catheter-Related Infections/microbiology , Catheters, Indwelling/microbiology , Child , Child, Preschool , Humans , Infant , Infant, Newborn , Parenteral Nutrition, Home/methods , Parenteral Nutrition, Home Total/methods
9.
JPEN J Parenter Enteral Nutr ; 36(4): 415-20, 2012 Jul.
Article in English | MEDLINE | ID: mdl-22301331

ABSTRACT

BACKGROUND: Vitamin K supplementation improves bone health, and its absence might be associated with low bone mineral density (BMD). The authors aim to assess vitamin K supplementation practices in Canadian home parenteral nutrition (HPN) programs and their relationship with BMD. METHODS: This is a cross-sectional study of 189 patients from the Canadian HPN registry. RESULTS: All 189 patients studied received M.V.I.-12, which does not contain vitamin K. Of those, 41.3% were supplemented with 10 mg of intravenous vitamin K (VK+) weekly, whereas the others did not receive vitamin K except via lipid emulsion (VK-). Short bowel syndrome accounted for 69% of VK+ and 46% of VK- patients. On univariate analysis, VK+ patients had substantially lower body mass index (BMI) and received lower bisphosphonate infusion than did VK-patients. There were no statistically significant differences in HPN calcium or lipid content, liver function test results, age, sex, or reason for HPN between the 2 groups. Patients who were VK+ had higher lumbar spine T scores and hip T scores than did VK-patients. General linear modeling analysis, adjusted for BMI, age, PN magnesium, PN phosphate, PN calcium, and bisphosphonate as possible predictors of BMD, showed a trend toward better hip T scores (P = .063) for VK+ patients compared with VK- patients. CONCLUSION: In HPN patients supplemented with vitamin K, the trend toward a better hip BMD compared with no supplementation suggests a role for vitamin K in preserving BMD. This requires further study.


Subject(s)
Bone Density/drug effects , Dietary Supplements , Parenteral Nutrition, Home Total/methods , Vitamin K/administration & dosage , Adult , Aged , Aged, 80 and over , Calcium, Dietary/administration & dosage , Canada , Cross-Sectional Studies , Diphosphonates/administration & dosage , Female , Hip , Humans , Lumbar Vertebrae/chemistry , Male , Middle Aged , Multivariate Analysis , Registries , Young Adult
10.
Nutr Hosp ; 27(5): 1655-7, 2012.
Article in Spanish | MEDLINE | ID: mdl-23478720

ABSTRACT

Patient diagnosed with Crohn's Disease with inflammatory pattern that evolves stenosing-piercing, causing abdominal perforation and fecal peritonitis. She was underwent to three surgeries, leading to numerous complications and a torpid clinical course. Given the state of malnutrition on admission it was prescribed Total Parenteral Nutrition (TPN), extending the administration for more than 10 months. In this period the TPN is suspended for 5 days, but the persistence of an enterocutaneous fistula causes the restoration of the TPN. After clinical stabilization, the patient is discharged to recover her nutritional status necessary to perform a bowel reconstruction surgery, continuing with TPN at home. After 7 and a half months, the patient with an optimal nutritional status, undergoes surgery, evolving favorably and suspending the TPN at 9 days.


Subject(s)
Crohn Disease/therapy , Parenteral Nutrition, Home Total/methods , Crohn Disease/surgery , Cutaneous Fistula/etiology , Digestive System Surgical Procedures , Female , Humans , Malnutrition/etiology , Malnutrition/therapy , Nutritional Status , Young Adult
11.
Clin Nutr ; 30(6): 714-7, 2011 Dec.
Article in English | MEDLINE | ID: mdl-21802801

ABSTRACT

The use of nutritional support in cancer patients has evolved since its introduction in the clinical practice 40 years ago. Both parenteral and enteral nutrition are now increasingly integrated within the main oncologic strategy with the aim of making surgery, chemotherapy and radiation therapy more safe and effective. This requires a better awareness of the inherent risk of starvation and undernutrition by the surgeons, medical oncologists and radiologists, the ability to implement a policy of nutritional screening of cancer patients and to propose them the nutritional support in a single bundle together with the oncologic drugs. Four different areas of nutritional intervention are now recognized which parallel the evolutionary trajectory of patients with tumour: the perioperative nutrition in surgical patients, the permissive nutrition in patients receiving chemotherapy and/or radiation therapy and the home parenteral nutrition which may be total (in aphagic-obstructed-incurable patients) or supplemental (in advanced weight-losing anorectic patients). Since cancer is a common disease and the continuous progress in medical therapy is changing its natural history, with more and more patients entering in a chronic and finally incurable phase where nutrition is determinant for survival, we can expect an increased demand for nutritional support in the next future.


Subject(s)
Medical Oncology/methods , Neoplasms/diet therapy , Nutritional Support/methods , Parenteral Nutrition, Home Total/methods , Humans , Medical Oncology/standards , Medical Oncology/trends , Nutritional Support/standards , Nutritional Support/trends , Parenteral Nutrition, Home Total/standards , Parenteral Nutrition, Home Total/trends
12.
Nutr Clin Pract ; 26(3): 273-85, 2011 Jun.
Article in English | MEDLINE | ID: mdl-21586412

ABSTRACT

Parenteral nutrition (PN) is commonly used in pediatric institutions in patients who either cannot be fed enterally or are unable to tolerate sufficient enteral calories to provide their nutrition requirements. Many pediatric patients, particularly those with short bowel syndrome or intestinal failure, will eventually require home PN (HPN) therapy. Although discharge to HPN is complex and can be associated with both immediate and long-term complications, it can be successfully achieved through collaboration between healthcare providers within the institution and the home care company and HPN education of the patient and caregivers. This review describes the processes that clinicians and institutions should consider when preparing for HPN discharge and serves as a guide for the effective transition to HPN in pediatric patients.


Subject(s)
Child Nutritional Physiological Phenomena , Nutritional Requirements , Parenteral Nutrition, Home Total/methods , Patient Education as Topic/methods , Teaching/methods , Caregivers , Child , Humans , Nutrition Assessment , Patient Discharge
13.
SEMERGEN, Soc. Esp. Med. Rural Gen. (Ed. impr.) ; 34(6): 311-317, jun. 2008. ilus, tab
Article in Es | IBECS | ID: ibc-66169

ABSTRACT

La nutrición artificial es un tratamiento de indicación hospitalaria que puede administrarse de manera puntual o permanente. Cada vez más, existen situaciones clínicas que permiten que los pacientes a los que se les administra este tratamiento puedan ser atendidos en su domicilio, suponiendo una mayor eficiencia y satisfacción del propio paciente y su familia.No obstante, la atención sanitaria, cuando se realiza en el domicilio del paciente, supone una dificultad para el nivel hospitalario, mientras que ya se realiza con normalidad desde la Atención Primaria.El diálogo y la coordinación entre ambos niveles asistenciales nos han llevado a la realización y puesta en práctica de un protocolo de atención conjunta para los pacientes en tratamiento con nutrición artificial domiciliaria, mediante el cual estamos convencidos de que estamos incrementando la calidad de la atención prestada. Los puntos más destacados del proceso de implementación se exponen en este artículo


Artificial nutrition is a hospital level treatment that can be administered short or long term. There are an increasing number of clinical situations that allow patients to receive this treatment in the home, meaning greater efficiency and satisfaction for the patient and family.However, while health care performed in the patient’s home is already a normal part of primary health care, hospital treatment at home supposes greater difficulty.Dialogue and coordination between both care levels haveled to the formulation and application of a protocol for combined care for patients receiving Artificial Nutrition treatment in the home. We are convinced that this is increasing the care quality given. The most outstanding points in the implementation process are presented in this article


Subject(s)
Humans , Parenteral Nutrition, Home Total/methods , Home Care Services, Hospital-Based , Nutritional Support/methods , Primary Health Care/methods , Intersectoral Collaboration , Clinical Protocols
14.
Endocrinol. nutr. (Ed. impr.) ; 55(supl.1): 45-51, ene. 2008. tab, graf
Article in Spanish | IBECS | ID: ibc-61171

ABSTRACT

El yodo es un oligoelemento esencial para la síntesis de hormonas tiroideas. La deficiencia de este oligoelemento es especialmente preocupante en el recién nacido, que debe sintetizar suficientes hormonas tiroideas para hacer frente a sus necesidades hormonales, ya que los preparados para alimentación de neonatos a término y prematuros no siempre contienen el yodo necesario. En el mundo, la mayor causa dehipotiroxinemia es la deficiencia de yodo, la cual está reconocida como la causa más importante de retraso mental y parálisis cerebral prevenible (AU)


Iodine is a trace element essential for the synthesis of thyroid hormones. Iodine deficiency is especially worrying inneonates, who must synthesize sufficient thyroid hormones to meet their hormonal requirements, since formula preparations for premature and term infants do not always contain adequate iodine. Worldwide, the main cause of hypothyroxinemia is iodine deficiency, which in turn is the main preventable cause of mental retardation and cerebral palsy(AU)


Subject(s)
Humans , Male , Female , Child , Infant, Newborn , Iodine Deficiency/drug therapy , Iodine Deficiency/prevention & control , Infant, Premature, Diseases/diet therapy , Infant, Premature/metabolism , Parenteral Nutrition, Home Total/methods , Parenteral Nutrition/methods , Hypothyroidism/diet therapy , Iodine Deficiency/diagnosis , Iodine Deficiency/therapy , Premature Birth/diet therapy , Premature Birth/epidemiology , Premature Birth/prevention & control , Maternal-Fetal Exchange/physiology
15.
JPEN J Parenter Enteral Nutr ; 31(6): 508-10, 2007.
Article in English | MEDLINE | ID: mdl-17947608

ABSTRACT

BACKGROUND: Many patients with advanced cancers have associated gastrointestinal (GI) obstruction. Parenteral nutrition (PN) is indicated in patients with a dysfunctional GI tract, but the role of PN in patients' survival is still controversial. The present study was retrospectively conducted to verify if there are any long-term survivors living for more than 1 year after initiation of PN without food or drink in patients with malignant GI tract obstruction resulting from advanced cancers. METHODS: One hundred fifteen adult patients with malignant GI obstruction were identified over a 6-year period at a palliative-care setting. Their median age was 51 years (range, 31-74 years), and 62 (54%) were women and 53 men (46%). All selected patients had malignant GI tract obstruction and started PN treatment after cessation of energy intake to time of death. Survival expectancy as a criterion was analyzed in all patients. RESULTS: The median time from initiation of PN to death was 6.5 months. Eleven patients survived >or=1 year and 2 patients have been alive for almost 4 years later after cessation of energy intake. CONCLUSIONS: PN can be expected to obtain a longer survival for the patient with GI tract obstruction caused by advanced cancer.


Subject(s)
Intestinal Obstruction/therapy , Neoplasms/complications , Palliative Care/methods , Parenteral Nutrition, Home Total/methods , Adult , Aged , Female , Humans , Intestinal Obstruction/etiology , Intestinal Obstruction/mortality , Male , Middle Aged , Neoplasms/mortality , Prognosis , Retrospective Studies , Survival , Survival Analysis , Time Factors
16.
Ned Tijdschr Geneeskd ; 149(8): 385-90, 2005 Feb 19.
Article in Dutch | MEDLINE | ID: mdl-15751316

ABSTRACT

Intestinal failure is characterised by inability of the intestine to absorb sufficient nutrients to maintain the integrity and function of the body. This can be caused by malabsorption due to too short an intestine or an abnormality of the mucosa, or by a severe motility disorder. In addition to dietary measures, the prescription of total parental nutrition (TPN) at home is sometimes necessary. This treatment is a burden on the patient and the risk of complications must be reduced to a minimum. The risks of long-term parenteral nutrition can be limited and the quality of the provision of services can be increased if the co-ordination is in the hands of a centre for home parenteral nutrition. In the Netherlands there are two centres for home-TPN: the St Radboud University Medical Centre in Nijmegen and the University Medical Centre (AMC) in Amsterdam. In both children and adults, the most common indications are the short bowel syndrome and motility disorders. However, the syndromes that cause this are clearly different in the different age groups. Parenteral nutrition can be given for long periods of time. A large variety of complications can occur, related especially to the equipment or the nutrients. When the nutrition is given via a central venous catheter, then sepsis is a serious and possibly life-threatening complication. In case of administration via an arteriovenous shunt, thrombosis of the shunt is the most frequent problem. If the treatment by means of home-TPN fails, then transplantation of the small intestine should be considered.


Subject(s)
Intestinal Diseases/therapy , Parenteral Nutrition, Home Total/methods , Adult , Child , Esophageal Motility Disorders/therapy , Humans , Intestinal Diseases/physiopathology , Intestines/physiopathology , Intestines/transplantation , Parenteral Nutrition, Home Total/adverse effects , Short Bowel Syndrome/therapy , Treatment Outcome
17.
Orv Hetil ; 144(31): 1545-9, 2003 Aug 03.
Article in Hungarian | MEDLINE | ID: mdl-14502869

ABSTRACT

UNLABELLED: At the rehabilitation hospital of Visegrád between 1996-2003 there were altogether 7 patients suffering from short bowel syndrome, 6 of them in the last 2 years. The purpose of this study is to demonstrate 2 cases of long-term total parental nutrition. One of the patients is a 60 year-old man, in whom gut resection has been performed because of acute arteria mesenterica superior occlusion. After gut resection 10 cm jejunum, a half colon transversum and the colon descendent were left. The central total parenteral nutrition has been going on for 365 days, for the last 255 days it has been performed at home: 2000 ml/day all-in-one nutrition solution + 500 ml oral high-fibre food preparation. At the beginning of the total parenteral nutrition the patient's weight was 64.5 kg (BMI: 23.5 kg/m2) which decreased to 51.5 kg (BMI: 18.5 kg/m2) owing to the reduction of the TPN to 1200 ml/day. This weight has been kept since then and the quality of life is satisfactory. Complication: increase of liver enzymes (GGT, ALP). The other patient is 48 years old with gut resection owing to art. mes. thrombosis. After gut resection 20 cm jejunum and the left side colon were left. The parenteral nutrition has been going on for 352 days (30 days were spent at home): 2000 ml all-in-one nutrition solution (the high-fibre oral nutrition solution was not tolerated in this case). The patient's weight is 54.5 kg (BMI: 18.33 kg/m2), ALP and GGT are getting back to normal. COMPLICATIONS: central venous tube sepsis which made it necessary to change the tube on several occasions.


Subject(s)
Body Weight , Intestinal Diseases/rehabilitation , Parenteral Nutrition, Home Total , Humans , Hungary , Intestinal Diseases/blood , Intestinal Diseases/surgery , Male , Middle Aged , Parenteral Nutrition, Home Total/adverse effects , Parenteral Nutrition, Home Total/methods , Weight Gain , Weight Loss
18.
Curr Gastroenterol Rep ; 2(4): 327-30, 2000 Aug.
Article in English | MEDLINE | ID: mdl-10981032

ABSTRACT

Home parenteral nutrition (HPN) support has been an advancing therapy in the past 30 years. Patients who previously had no options to sustain their lives are now able to live at home, maintain employment, and continue with most daily activities. Although this therapy has been innovative and successful, it requires great financial and professional resources. The expense of HPN makes most patients dependent on third-party payment, and the complications can result in frequent hospitalizations and may be life-threatening. For these reasons, extensive training of the patient and caregivers is necessary. Thorough and time-consuming monitoring by a multidisciplinary team of professionals is also essential. Home care and supply companies offer services that make the process of home TPN easier for the patient and the healthcare team. Advances in the area of home nutrition support are expected to continue as the demand for this therapy rises.


Subject(s)
Home Care Services, Hospital-Based , Parenteral Nutrition, Home Total , Humans , Monitoring, Physiologic , Parenteral Nutrition, Home Total/adverse effects , Parenteral Nutrition, Home Total/methods , Patient Discharge
20.
Nutrition ; 12(4): 245-9, 1996 Apr.
Article in English | MEDLINE | ID: mdl-8862529

ABSTRACT

The requirements for essential fatty acids in patients on home parenteral nutrition are not well described. We therefore studied the needs of 12 patients receiving parenteral nutrition for at least 4 mo (range: 4 mo-17.3 yr; mean 7.0 +/- 5.2 yr). Prior to the study, each patient had been receiving intravenous lipids either weekly or biweekly and had a triene to tetraene ratio (TTR) on plasma phospholipids performed at least annually. A TTR > or = 0.2 was considered diagnostic for essential fatty acid deficiency (EFAD). The purpose of this study was to determine the required intravenous lipid supplementation in patients on home total parenteral nutrition (HTPN). Patients with an initial TTR of < 0.2 had their intravenous lipid stopped and changes in their serum phospholipid fatty acids were followed every 3-4 wk. Nine of 12 patients had TTRs > 0.2 at some point in the study. Phase I consisted of patients who at initiation of the study had normal TTRs and were taken off lipid supplementation until their TTR became abnormal. Phases II, III, IV, and V consisted of lipid delivered in total nutrient admixtures in biweekly doses of 0.6, 1.2, 1.8, and 2.4 g of fat/kg bodyweight, respectively. Eight patients normalized their TTRs on the biweekly lipid regimens; one patient expired before his ratio normalized; and three patients could not be made deficient in essential fatty acids after 26 or more wk of fat-free parenteral nutrition. Most patients required 1.2 to 2.4 g of lipid/kg bodyweight/biweekly to correct serologic EFAD. The clinical background, as well as the length of small bowel remaining, did not seem to identify those patients who required lipid supplementation nor the final dose of lipid needed to normalize their TTRs.


Subject(s)
Fatty Acids, Essential/administration & dosage , Fatty Acids, Essential/deficiency , Parenteral Nutrition, Home Total , Adult , Aged , Fat Emulsions, Intravenous/administration & dosage , Fatty Acids, Essential/blood , Female , Humans , Male , Middle Aged , Nutritional Requirements , Parenteral Nutrition, Home Total/adverse effects , Parenteral Nutrition, Home Total/methods , Phospholipids/blood , Phospholipids/chemistry , Time Factors
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