ABSTRACT
Two novel secondary metabolites, compounds (1-2) were isolated from the roots of Paronychia chionaea. On the basis of spectroscopic data including 1D and 2D NMR experiments (COSY, TOCSY, HSQC, and HMBC), and mass spectroscopy, their structures were established as 6-C-[alpha-L-arabinopyranosyl-( 1 --> 2)-beta-D-glucopyranosyl]-7-O-[beta-D-glucopyranosyl]-luteolin 3'-methyl ether (1), and 2-(methoxy)-2-(3,5-dimethoxy 4-hydroxyphenyl)-ethane-1,2-diol 1-O-beta-D-glucopyranoside (2).
Subject(s)
Glycosides/isolation & purification , Paronychia/metabolism , Glycosides/chemistry , Magnetic Resonance Spectroscopy , Plant Roots/metabolismABSTRACT
Two new oleanane saponins (1 and 2) and one new flavonol glycoside (3) together with six known flavonoids, were isolated from the aerial parts of Paronychia argentea. Their structures were elucidated by 1D and 2D NMR experiments including 1D-TOCSY, DQF-COSY, NOESY, HSQC, and HMBC spectroscopy, as well as ESI-MS analysis.
Subject(s)
Flavonoids/isolation & purification , Paronychia/metabolism , Saponins/isolation & purification , Flavonoids/chemistry , Magnetic Resonance Spectroscopy , Molecular Structure , Plant Components, Aerial/metabolism , Saponins/chemistry , Spectrometry, Mass, Electrospray IonizationABSTRACT
Bazex's paraneoplastic acrokeratosis is a syndrome with psoriasiform acral hyperkeratosis and nail changes associated with carcinoma of the upper respiratory or alimentary tract. We report here a case where amino acid analysis of the hyperkeratotic and friable nails differed from normal and other diseased nails investigated by us, but they were similar to those reported in trichothiodystrophy or the BIDS syndrome.
