Sexually transmitted diseases including genital papillomavirus infection in male sexual partners of women treated for cervical intraepithelial neoplasia III by conization.

History and clinical prevalence of sexually transmitted diseases (STD), including genital human papillomavirus (HPV) infection, were studied in 60 sexual partners of 60 women previously treated for cervical intraepithelial neoplasia (CIN) III by conization. Investigations included serological and bacteriological screening, histopathology and colposcopy. A history of STD was reported by 20 men (33%), and 34 (57%) had signs of STD including genital HPV infection, 2 (3%) had a chlamydial infection, one had molluscum contageosum, 7 (12%) had genital warts and 24 (40%) had abnormal acetowhite epithelium, indicating HPV infection. The HPV lesions were principally subclinical and located on the glans penis and the prepuce. Colposcopy and application of acetic acid are essential for detection. The gynaecologist and venereologist must recognize the sexually transmitted nature of CIN, and the causal link between CIN and HPV infection. Assessment and treatment of the male sexual partner of women treated for CIN might be an essential part in disease control with the aim of preventing cervical cancer.

Magnified penile surface scanning in diagnosis of penile condyloma.

To determine the incidence of penile condyloma in a group of high risk males, we have performed magnified penile surface scanning and biopsy of suspicious lesions in 51 men. All men were partners of women with proven condyloma. Of these men, 45 were found to have histologic evidence of condyloma, only 8 of which were grossly visible.

Colposcopy in the diagnosis of penile condyloma.

To determine the incidence of penile condyloma in a group of high-risk men, we carried out colposcopy and biopsy of suspicious lesions in 51 men. All men were partners of women with condyloma. Of these men, 45 were found to have histologic evidence of condyloma, and only eight of these had grossly visible disease.

PIP: The frequency of penile condyloma in the male partners of women referred for evaluation of abnormal Papanicolaou smears from April-October 1984 at Pennsylvania Hospital was prospectively evaluated. All 51 men examined had elevated white penile lesions colposcopically consistent with a diagnosis of condyloma. Histologic evidence of condyloma was found in 45 of these men. The findings in men with suspicious lesions that were not condyloma included chronic inflammation, dilated sweat duct, lichen nitidus, verruca vulgaris, and penile skin tag. Only 8 of the 45 confirmed lesions were identifiable with the naked eye; the remainder required magnification and acetic acid for visualization. Cytologic evidence of abnormal epithelium was detected in 13 men. The mean age at 1st coitus among those men with penile condyloma was 17.5 years; the mean number of sexual partners was 14.7. In men, treatment of condyloma encompasses YAG laser, 5-fluorouracil cream, carbon dioxide laser, and podophyllin. In women, management is dependent on whether atypical mitotic figures are present or absent; in the former cases, carbon dioxide laser is appropriate, while in the latter cases, cryotherapy or topical 5-fluorouracil cream is recommended.

Condyloma acuminatum of the oral cavity: a case report.

A 24-year-old man developed condyloma acuminatum on his penis and on the upper lip of his mouth approximately three months after his girl friend was diagnosed and treated for vaginal warts. Cunnilingus was the postulated method of spread to the lip. Condyloma acuminatum should be considered among the many sexually transmitted infections that affect both anogenital and oral areas.