Subject(s)
Fovea Centralis/drug effects , Nitrates/poisoning , Pentanols/poisoning , Sexual Behavior/drug effects , Vision Disorders/chemically induced , Administration, Inhalation , Adult , Fovea Centralis/pathology , Humans , Male , Nitrates/administration & dosage , Pentanols/administration & dosage , Urological Agents/administration & dosage , Urological Agents/poisoning , Vision Disorders/pathologySubject(s)
Methemoglobinemia/chemically induced , Nitrates/poisoning , Pentanols/poisoning , Female , Humans , MaleABSTRACT
We wish to report two cases of methaemoglobinaemia secondary to amyl nitrate use. A 55-year-old male presented with saturations in the mid 80s despite FiO2 of 1.0 and GCS 10 and a 22-year-old female who presented with fluctuating GCS and a slate grey colour. Both were found to have high levels of metheamoglobinaemia on ABG, were treated with methylene blue and made excellent recoveries. These cases illustrate the risk of methaemoglobinaemia secondary to amyl nitrate. Appropriate and prompt management can lead to very good outcomes.
Subject(s)
Methemoglobinemia/chemically induced , Nitrates/poisoning , Pentanols/poisoning , Enzyme Inhibitors/administration & dosage , Female , Humans , Injections, Intravenous , Male , Methemoglobinemia/drug therapy , Methylene Blue/administration & dosage , Middle Aged , Young AdultSubject(s)
Cyanosis/chemically induced , Cyanosis/diagnosis , Hypotension/chemically induced , Hypotension/diagnosis , Methemoglobinemia/chemically induced , Methemoglobinemia/diagnosis , Nitrates/poisoning , Pentanols/poisoning , Administration, Oral , Cyanosis/prevention & control , Diagnosis, Differential , Humans , Hypotension/prevention & control , Male , Methemoglobinemia/prevention & control , Middle Aged , Nitrates/administration & dosage , Pentanols/administration & dosageSubject(s)
Basal Ganglia Diseases/chemically induced , Brain/drug effects , Gas Poisoning/diagnosis , Neurotoxins/poisoning , Pentanols/poisoning , Acetylcholine/metabolism , Adult , Autonomic Nervous System Diseases/chemically induced , Autonomic Nervous System Diseases/physiopathology , Basal Ganglia Diseases/physiopathology , Biperiden/therapeutic use , Brain/physiopathology , Gas Poisoning/physiopathology , Gas Poisoning/therapy , Humans , Male , Military Personnel , Muscarinic Antagonists/therapeutic use , Muscle Rigidity/chemically induced , Muscle Rigidity/physiopathology , Occupational Exposure , Synaptic Transmission/drug effectsABSTRACT
An autoerotic fatality due to mechanical compression of the neck by a sophisticated construction used for breath control games is reported. The presence of signs of methemoglobinemia as well as an empty "poppers" flask found beside the passed indicated the use of volatile nitrites to enhance sexual pleasure. It was assumed that vasodilatation had caused a sudden unconsciousness with consecutive hanging.
Subject(s)
Accidents/legislation & jurisprudence , Asphyxia/pathology , Fetishism, Psychiatric/pathology , Illicit Drugs/poisoning , Masturbation/pathology , Methemoglobinemia/pathology , Neck Injuries/pathology , Nitrates/poisoning , Pentanols/poisoning , Adult , Cause of Death , Diagnosis, Differential , Gastrointestinal Contents/chemistry , Humans , Illicit Drugs/analysis , Male , Masochism , Methemoglobin/analysis , Nitrates/analysis , Pentanols/analysis , Sadism , Skin/injuries , Skin/pathologyABSTRACT
Methaemoglobinaemia is rare but should be considered in cases of cyanosis unresponsive to oxygen therapy. An example of this is given involving the accidental ingestion of Amyl Nitrite.
