ABSTRACT
BACKGROUND: The most freq+uent disorders and injuries requiring the joint attention of general surgeons and neurosurgeons are presented and analysed in this review. METHODS: The priorities and prognosis concerning diagnostic and surgical measures for patients in coma with multiple injuries, extra- and intraspinal tumours and brain metastases are analysed. RESULTS: The urgency of general surgical and neurosurgical measures is not ruled by a preformatted pattern but by the vital needs of the individual patient. CONCLUSION: The differentiation of vital from non-vital operations or with regard to prognosis necessary from inadequate general surgical and neurosurgical measures is of fundamental importance. The successive order of general surgical and neurosurgical interventions must be adjusted to the needs of each individual patient.
Subject(s)
Cooperative Behavior , General Surgery , Interdisciplinary Communication , Neurosurgery , Brain Death/diagnosis , Brain Neoplasms/secondary , Brain Neoplasms/surgery , Craniocerebral Trauma/diagnosis , Craniocerebral Trauma/surgery , Emergencies , Humans , Persistent Vegetative State/diagnosis , Persistent Vegetative State/surgery , Prognosis , Spinal Neoplasms/secondary , Spinal Neoplasms/surgeryABSTRACT
OBJECTIVE: On the basis of the findings of the electrophysiological evaluation of vegetative state (VS) and minimally conscious state (MCS), the effect of deep brain stimulation (DBS) was examined according to long-term follow-up results. The results of spinal cord stimulation (SCS) on MCS was also examined and compared with that of DBS. METHODS: One hundred seven patients in VS and 21 patients in MCS were evaluated neurologically and electrophysiologically over 3 months after the onset of brain injury. Among the 107 VS patients, 21 were treated by DBS. Among the 21 MCS patients, 5 were treated by DBS and 10 by SCS. RESULTS: Eight of the 21 patients recovered from VS and were able to follow verbal instructions. These eight patients showed desynchronization on continuous electroencephalographic frequency analysis. The Vth wave of the auditory brainstem response and N20 of somatosensory evoked potential were recorded even with a prolonged latency, and pain-related P250 was recorded with an amplitude of more than 7 µV. In addition, DBS and SCS induced a marked functional recovery in MCS patients who satisfied the electrophysiological inclusion criteria. CONCLUSION: DBS for VS and MCS patients and SCS for MCS patients may be useful, when the candidates are selected on the basis of the electrophysiological inclusion criteria. Only 16 (14.9%) of the 107 VS patients and 15 (71.4%) of the 21 MCS patients satisfied the electrophysiological inclusion criteria.
Subject(s)
Deep Brain Stimulation/methods , Persistent Vegetative State/surgery , Spinal Cord Stimulation/methods , Adolescent , Adult , Aged , Aged, 80 and over , Deep Brain Stimulation/adverse effects , Electric Stimulation , Electroencephalography , Electrophysiological Phenomena , Evoked Potentials, Auditory, Brain Stem/physiology , Evoked Potentials, Somatosensory/physiology , Female , Follow-Up Studies , Humans , Male , Middle Aged , Persistent Vegetative State/psychology , Recovery of Function , Reticular Formation/physiology , Spinal Cord Stimulation/adverse effects , Treatment Outcome , Young AdultSubject(s)
Brain , Persistent Vegetative State/diagnosis , Persistent Vegetative State/surgery , Stem Cell Transplantation/methods , Brain/blood supply , Brain/diagnostic imaging , Brain/pathology , Cerebrovascular Circulation/physiology , Humans , Magnetic Resonance Imaging , Positron-Emission Tomography , Tomography, X-Ray ComputedABSTRACT
The paper presents a clinical case with a good outcome, which shows the advantages of active and stepwise surgical policy in concomitant chronic extra- and intracranial pyoinflammatory and dystrophic complications with severe liquorocirculatory disorders and extensive skull defect due to severe brain injury.
Subject(s)
Craniocerebral Trauma/complications , Craniocerebral Trauma/surgery , Adult , Brain/diagnostic imaging , Electroencephalography , Humans , Hydrocephalus/etiology , Hydrocephalus/surgery , Male , Neurosurgical Procedures , Persistent Vegetative State/surgery , Skull Fractures/complications , Skull Fractures/surgery , Tomography, X-Ray Computed , Treatment OutcomeABSTRACT
The paper presents new results of embryonic tissue transplantation. Twenty-seven embryonic tissue transplantations into affected regions of brain cortex were performed on 21 patients with apallic syndrome. Motor and mental improvement were observed in sixteen recipients.