1.
Br J Dermatol
; 144(1): 143-5, 2001 Jan.
Article
in English
| MEDLINE
| ID: mdl-11167696
ABSTRACT
Smith-Lemli-Opitz (SLO) affected children have multiple congenital physical and mental abnormalities; photosensitivity to ultraviolet A (UVA) has recently become a recognized feature. We present a patient with SLO and prominent photosensitivity in whom detailed phototesting has been performed at baseline and following 6 months of cholesterol supplementation. There was significant improvement in the symptoms of photosensitivity, confirmed objectively by phototesting and accompanied by partial correction of the biochemical abnormalities seen in SLO. This case report is the first to show that cholesterol supplementation in SLO can lead to an objective improvement in the associated photosensitivity.
Subject(s)
Cholesterol, Dietary/therapeutic use , Dietary Supplements , Photosensitivity Disorders/diet therapy , Smith-Lemli-Opitz Syndrome/diet therapy , Adult , Follow-Up Studies , Humans , Male
2.
Br J Dermatol
; 143(6): 1340, 2000 Dec.
Article
in English
| MEDLINE
| ID: mdl-11122059
3.
Contact Dermatitis
; 4(5): 305, 1978 Oct.
Article
in English
| MEDLINE
| ID: mdl-754711