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Int J Food Sci Nutr ; 60 Suppl 6: 126-36, 2009.
Article in English | MEDLINE | ID: mdl-19548163

ABSTRACT

The effects of ingestion of flaxseed gum on blood glucose and cholesterol, particularly low-density lipoprotein cholesterol, in type 2 diabetes were evaluated. Flaxseed gum was incorporated in wheat flour chapattis. Sixty patients of type 2 diabetes were fed a daily diet for 3 months, along with six wheat flour chapattis containing flaxseed gum (5 g), as per the recommendations of the American Diabetic Association. The control group (60 individuals) consumed an identical diet but the chapattis were without gum. The blood biochemistry profiles monitored before starting the study and at monthly intervals showed fasting blood sugar in the experimental group decreased from 154 ± 8 mg/dl to 136 ± 7 mg/dl (P=0.03) while the total cholesterol reduced from 182 ± 11 mg/dl to 163 ± 9 mg/dl (P=0.03). Results showed a decrease in low-density lipoprotein cholesterol from 110 ± 8 mg/dl to 92 ± 9 mg/dl (P=0.02). The study demonstrated the efficacy of flax gum in the blood biochemistry profiles of type 2 diabetes.


Subject(s)
Anticholesteremic Agents/therapeutic use , Diabetes Mellitus, Type 2/diet therapy , Flax/chemistry , Hypoglycemic Agents/therapeutic use , Plant Gums/therapeutic use , Plant Mucilage/therapeutic use , Seeds/chemistry , Anticholesteremic Agents/administration & dosage , Anticholesteremic Agents/economics , Anticholesteremic Agents/isolation & purification , Bread/analysis , Bread/economics , Cholesterol, LDL/blood , Diabetes Mellitus, Type 2/blood , Diabetes Mellitus, Type 2/complications , Diet/ethnology , Female , Food Preferences/ethnology , Food, Formulated/analysis , Food, Formulated/economics , Food-Processing Industry/economics , Humans , Hypercholesterolemia/complications , Hypercholesterolemia/prevention & control , Hypoglycemic Agents/administration & dosage , Hypoglycemic Agents/economics , Hypoglycemic Agents/isolation & purification , India , Industrial Waste/analysis , Industrial Waste/economics , Male , Medicine, Ayurvedic , Middle Aged , Pilot Projects , Plant Gums/administration & dosage , Plant Gums/economics , Plant Gums/isolation & purification , Plant Mucilage/administration & dosage , Plant Mucilage/economics , Plant Mucilage/isolation & purification
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