ABSTRACT
A 2-year-old, female goat from Connecticut was submitted for necropsy with a 5-day history of pyrexia and intermittent neurologic signs, including nystagmus, seizures, and circling. Postmortem examination revealed suppurative meningitis. Histologic examination of the brain revealed that the meninges were diffusely infiltrated by moderate numbers of lymphocytes, macrophages, and fibrin, with scattered foci of dense neutrophilic infiltrate. Culture of pus and brainstem yielded typical mycoplasma colonies. DNA sequencing of the 16S ribosomal RNA gene revealed 99% sequence homology with Mycoplasma mycoides subspecies capri and Mycoplasma mycoides subspecies mycoides Large Colony biotype, which are genetically indistinguishable and likely to be combined as a single subspecies labeled M. mycoides subsp. capri. The present case is unusual in that not only are mycoplasma an uncommon cause of meningitis in animals, but additionally, in that all other reported cases of mycoplasma meningitis in goats, systemic lesions were also present. In the present case, meningitis was the only lesion, thus illustrating the need to consider mycoplasma as a differential diagnosis for meningitis in goats.
Subject(s)
Goat Diseases/microbiology , Meningitis, Bacterial/veterinary , Mycoplasma mycoides , Pleuropneumonia, Contagious/complications , Animals , Brain/pathology , Female , Goat Diseases/pathology , Goats/microbiology , Meningitis, Bacterial/etiology , Meningitis, Bacterial/microbiology , Meningitis, Bacterial/pathology , Mycoplasma mycoides/genetics , Mycoplasma mycoides/isolation & purification , Phylogeny , Pleuropneumonia, Contagious/microbiology , Pleuropneumonia, Contagious/pathology , RNA, Ribosomal, 16S/geneticsSubject(s)
Cattle Diseases/pathology , Goats/microbiology , Mycoplasma Infections/veterinary , Pleuropneumonia, Contagious/pathology , Animals , Cattle , Cattle Diseases/microbiology , Lung/pathology , Mycoplasma mycoides/isolation & purification , Pleura/pathology , Pleuropneumonia, Contagious/complications , Pleuropneumonia, Contagious/microbiology , Trypanosomiasis, Bovine/complicationsABSTRACT
Although the hallmark of Mycoplasma pneumoniae infection is pneumonia, the organism is also responsible for a protean array of other symptoms. With an increased awareness of the board clinical spectrum of M. pneumoniae disease and the ready availability of the cold agglutinin and M. pneumoniae complement-fixation tests, interested clinicians will note additional clinical-mycoplasmal associations in their patients.
Subject(s)
Mycoplasma Infections/diagnosis , Pleuropneumonia, Contagious/diagnosis , Adolescent , Adult , Agglutination Tests , Anemia, Hemolytic/etiology , Animals , Arthritis, Infectious/etiology , Central Nervous System Diseases/etiology , Child , Child, Preschool , Complement Fixation Tests , Heart Diseases/etiology , Humans , Lung Abscess/etiology , Otitis Media/etiology , Pancreatitis/etiology , Pleuropneumonia, Contagious/complications , Pleuropneumonia, Contagious/therapy , Respiratory Tract Infections/etiology , Sinusitis/etiology , Skin ManifestationsSubject(s)
Blood Coagulation , Blood Platelets , Cattle Diseases/complications , Fibrinogen , Mycoplasma Infections/veterinary , Pleuropneumonia, Contagious/veterinary , Thrombosis/etiology , Animals , Blood Cell Count/veterinary , Blood Proteins , Cattle , Cattle Diseases/blood , Female , Fibrin Fibrinogen Degradation Products , Fibrinolysis , Hematocrit , Hemoglobins , Lung/pathology , Mycoplasma mycoides , Pleuropneumonia, Contagious/blood , Pleuropneumonia, Contagious/complications , Prothrombin Time , Thrombin , Thromboplastin , Thrombosis/bloodABSTRACT
A 48-year-old patient presented with pneumonia and pleural effusion due to Mycoplasma pneumoniae, and subsequently developed pharyngitis and electrocardiographic evidence of myocarditis. The sparse literature on mycoplasma myocarditis is reviewed. The clinical features, electrocardiographic changes and prognosis are discussed.
