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1.
Acta Medica (Hradec Kralove) ; 63(3): 128-132, 2020.
Article in English | MEDLINE | ID: mdl-33002400

ABSTRACT

The clinical presentation of iron deficiency can be very heterogeneous, including various oral and other mucosal problems. Here, in this case, we report the patient with burning mouth and dysphagia symptoms where iron deficiency was found to be the underlying cause after several months of investigations. This clinical syndrome is called Plummer-Vinson syndrome. It is sporadic with an incidence less than 0.1% of patients suffering from iron deficiency anemia.


Subject(s)
Deglutition Disorders , Esophagus , Iron , Mouth Diseases , Plummer-Vinson Syndrome , Aged , Anemia, Iron-Deficiency/diagnosis , Anemia, Iron-Deficiency/etiology , Deglutition Disorders/diagnosis , Deglutition Disorders/etiology , Diagnosis, Differential , Esophagus/diagnostic imaging , Esophagus/pathology , Female , Humans , Iron/blood , Iron/therapeutic use , Iron Deficiencies , Mouth Diseases/diagnosis , Mouth Diseases/etiology , Mouth Diseases/therapy , Patient Care Management/methods , Plummer-Vinson Syndrome/diagnosis , Plummer-Vinson Syndrome/physiopathology , Trace Elements/therapeutic use , Treatment Outcome
4.
Tunis Med ; 85(5): 402-4, 2007 May.
Article in French | MEDLINE | ID: mdl-17657927

ABSTRACT

BACKGROUND: Plummer Vinson syndrome is a rare affection which affects mainly white women. It is characterized by dysphagia, iron deficiency and the presence of superior esophageal web. AIM: The purpose of this study is to precise the epidemiological, clinical, paraclinical and therapeutical features of the affection. METHODS: We report 19 cases of Plummer Vinson syndrome collected over 15 years (1990- 2004). RESULTS: Dysphagia is the main symptom observed in 100% of the cases. 89.4% of the patients had anemia and 15 hyposideremy. All the patients were treated with iron supplementation and endoscopic treatment (dilatation and rupture of esophageal webs). Three patients necessitate multiple sessions of endoscopic dilatation and 15 had favourable evolution. The malignancy was observed in one case.


Subject(s)
Plummer-Vinson Syndrome/diagnosis , Adult , Anemia, Iron-Deficiency/diagnosis , Carcinoma, Squamous Cell/complications , Catheterization , Deglutition Disorders/diagnosis , Esophageal Neoplasms/complications , Esophagoscopy , Esophagus/abnormalities , Esophagus/physiopathology , Female , Gastrointestinal Transit/physiology , Hemoglobins/analysis , Humans , Middle Aged , Mouth Neoplasms/complications , Plummer-Vinson Syndrome/physiopathology , Plummer-Vinson Syndrome/therapy , Retrospective Studies
5.
J Assoc Physicians India ; 53: 991-2, 2005 Nov.
Article in English | MEDLINE | ID: mdl-16515242

ABSTRACT

The association of Paterson Brown Kelly Syndrome and celiac disease is not widely reported. Both the entities have iron deficiency anemia. This case report emphasizes the need of screening for celiac disease in patients with Paterson Kelly Syndrome.


Subject(s)
Anemia, Iron-Deficiency/physiopathology , Celiac Disease/diagnosis , Plummer-Vinson Syndrome/diagnosis , Adult , Celiac Disease/physiopathology , Diagnosis, Differential , Duodenum/pathology , Female , Humans , Intestinal Mucosa/pathology , Plummer-Vinson Syndrome/physiopathology
6.
J. bras. med ; 79(3): 46-51, set. 2000. ilus
Article in Portuguese | LILACS | ID: lil-296376

ABSTRACT

A síndrome de Plummer-Vinson é uma entidade clínica caracterizada por disfagia, membranas esofágicas e anemia ferropriva. Esta síndrome está associada com aumento no risco de câncer no trato alimentar superior. Os autores relatam um caso, revisam a literatura e apresentam uma discussão sobre a etiopatia, diagnóstico, tratamento e prognóstico dessa afecção


Subject(s)
Humans , Plummer-Vinson Syndrome/diagnosis , Plummer-Vinson Syndrome/physiopathology , Plummer-Vinson Syndrome/therapy , Deglutition Disorders/physiopathology
8.
Dig Dis Sci ; 38(5): 968-71, 1993 May.
Article in English | MEDLINE | ID: mdl-8482199

ABSTRACT

We report the case of a 41-year-old woman with Plummer-Vinson syndrome and an esophageal motility disorder. She complained of dysphagia and odynophagia and had cheilitis, glossitis, and hypochromic anemia. An esophageal motility study showed low amplitude of contraction and high intrabolus pressure in the esophageal body. After iron replacement, the patient was free from symptoms, and a new motility study showed increased amplitude of contraction and decreased intrabolus pressure.


Subject(s)
Esophagus/physiopathology , Iron/therapeutic use , Plummer-Vinson Syndrome/drug therapy , Plummer-Vinson Syndrome/physiopathology , Adult , Anemia, Hypochromic/complications , Anemia, Hypochromic/drug therapy , Female , Humans , Manometry , Muscle Contraction/drug effects
9.
Ann Otol Rhinol Laryngol ; 99(1): 51-4, 1990 Jan.
Article in English | MEDLINE | ID: mdl-2294834

ABSTRACT

Plummer-Vinson syndrome (PVS) is characterized by iron deficiency anemia, upper esophageal stricture, cervical dysphagia, and glossitis. The precise role of iron deficiency in PVS has yet to be defined and remains a subject of much debate. A 29-year-old woman with PVS is presented. The patient had a 4-year history of severe iron deficiency anemia, a 2-year history of progressive dysphagia and weight loss, and a greater than 90% benign upper esophageal stricture. Iron therapy alone resolved her dysphagia and anemia, and a follow-up esophagram 1 year later showed a residual stenosis of less than 30%. The development of severe iron deficiency anemia in this patient 2 years before the onset of dysphagia, as well as the response of the stricture to iron repletion, supports the theory that iron deficiency can cause dysphagia and upper esophageal strictures. The occurrence of glossitis, gastritis, and esophagitis in iron deficiency demonstrates the adverse effects of iron depletion on the rapidly proliferating cells of the upper alimentary tract.


Subject(s)
Anemia, Hypochromic/therapy , Deglutition Disorders/therapy , Iron/therapeutic use , Plummer-Vinson Syndrome/therapy , Adult , Anemia, Hypochromic/complications , Deglutition , Deglutition Disorders/complications , Esophageal Stenosis/complications , Esophageal Stenosis/pathology , Esophagus/pathology , Female , Humans , Plummer-Vinson Syndrome/complications , Plummer-Vinson Syndrome/pathology , Plummer-Vinson Syndrome/physiopathology
10.
Laryngoscope ; 98(9): 994-8, 1988 Sep.
Article in English | MEDLINE | ID: mdl-3412097

ABSTRACT

In Plummer-Vinson syndrome, esophagography often reveals a web at the anterior wall of the cervical esophagus. The pathogenesis of the esophageal web and the cause of dysphagia in this syndrome were investigated radiographically, endoscopically, manometrically, and histologically. It was considered that the web seen in the esophagogram may have been formed due to the restriction of dilation of the esophageal wall, which results from repetitive inflammation and the subsequent healing process. Dysphagia in this syndrome may be explained by a decrease in swallowing power. Iron deficiency anemia may play the main role in the above histological changes and the resulting decrease in swallowing power.


Subject(s)
Deglutition Disorders/diagnostic imaging , Esophagus/diagnostic imaging , Plummer-Vinson Syndrome/diagnostic imaging , Adult , Esophagoscopy , Esophagus/pathology , Esophagus/physiopathology , Female , Humans , Manometry , Middle Aged , Plummer-Vinson Syndrome/pathology , Plummer-Vinson Syndrome/physiopathology , Radiography
12.
Dig Dis Sci ; 24(12): 959-63, 1979 Dec.
Article in English | MEDLINE | ID: mdl-510098

ABSTRACT

A patient is presented with Barrett's esophagus (lower esophagus lined with columnar epithelium) who also has a band of columnar epithelium in the upper esophagus separated from that below by normal squamous epithelium in the midesophagus. The upper most squamocolumnar junction coincided with or formed a mucosal ring as seen at endoscopy. This ring, which was first seen on barium swallow, has the radiographic appearance of that associated with the Paterson-Kelly syndrome. This patient's unique findings may provide further insight into the etiology of upper esophageal webs or rings (Paterson-Kelly syndrome).


Subject(s)
Deglutition Disorders/physiopathology , Esophageal Diseases/physiopathology , Esophagus/physiopathology , Gastric Mucosa/physiopathology , Plummer-Vinson Syndrome/physiopathology , Aged , Endoscopy , Esophageal Diseases/diagnosis , Female , Humans , Plummer-Vinson Syndrome/diagnosis
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