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Lik Sprava ; (7): 71-4, 1992 Jul.
Article in Russian | MEDLINE | ID: mdl-1448994

ABSTRACT

The authors suggest two stages of ecological and hygienic evaluation of surface active substances widely used in oil extraction. Stage 1. Toxicological-hygienic evaluation of these substances. Stage 2. Ecological-hygienic aspects of surface active substances (migration into soil, phytotoxicity, effect on the water quality and oth.). It was established at stage 1 that proxanol, proxamin, diproxamin are compounds of minor hazard (class 4 hazard). These substances belong to local skin-irritating substances. Proxanol produces skin-resorptive effects which is confirmed by clinical signs of intoxication, reduction of weight of the experimental animals.


Subject(s)
Amines , Lipids , Petroleum , Surface-Active Agents/toxicity , Animals , Dose-Response Relationship, Drug , Poisoning/physiopathology , Poloxalene/poisoning , Poloxalene/toxicity , Rats , Skin/drug effects , Surface-Active Agents/poisoning , Time Factors
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