1.
Farmakol Toksikol
; 44(4): 470-3, 1981.
Article
in Russian
| MEDLINE
| ID: mdl-7286209
ABSTRACT
A Soviet low-molecular weight polymeric preparation polyvinylpyridine-N-oxide in doses producing a marked antisilicotic effect (1 g/kg bw, 5 injections for 2 weeks or inhalations at a concentration of 57.9 +/- 4.11 mg/m3 for one hour a day 5 times a week over 8 months or throughout the entire pregnancy) does not affect generative function of rats or mice and progeny of two generations.
Subject(s)
Polyvinylpyridine N-Oxide/toxicity , Polyvinyls/toxicity , Reproduction/drug effects , Animals , Dose-Response Relationship, Drug , Embryo, Mammalian/drug effects , Female , Growth/drug effects , Male , Mice , Mutagenicity Tests , Ovary/drug effects , Pregnancy , Rats , Spermatozoa/drug effects , Testis/drug effects , Time Factors
2.
Gig Tr Prof Zabol
; (4): 50-2, 1977 Apr.
Article
in Russian
| MEDLINE
| ID: mdl-858515