Subject(s)
Philately , Prognathism/history , Austria , Famous Persons , History, 16th Century , History, 17th Century , History, 18th Century , History, 19th Century , Humans , Prognathism/genetics , SpainABSTRACT
Impacted teeth are frequently found in humans today, but current data suggest their existance in skulls originating from the prehistoric age. This report describes the skull of an adult female that was found during excavation in the Croation enolithic site of Vucedol (2700-24--BC). The skull is well preserved and, according to cranial and facial index calculation, is classified as dolichocephalic and mesoprospic. Cephalometric analysis revealed bimaxillary prognathism. The maxillary left canine is impacted and its crown peak is visible through the alveolar maxillary bone fenestration. The position of the canine was verified using x-rays, and is described in this study as an isolated finding. The reported occurrence of impacted teeth in prehistoric material appears to confirm the multifactorial etiology of this anomaly.
Subject(s)
Cuspid , Tooth, Impacted/history , Adult , Cephalometry , Croatia , Female , History, Ancient , Humans , Paleodontology , Paleopathology , Prognathism/history , Prognathism/pathologyABSTRACT
Mandibular prognathism is assumed to be a polygenic trait in the vast majority of cases. In a few families, this phenotype and perhaps a syndrome with a broader spectrum of facial anomalies seems to be determined by a single dominant gene of very low frequency (McKusick No *176700). The phenotype is known to have occurred independently in several European noble families. We constructed a pedigree comprising 13 of these families with 409 members in 23 generations in which mandibular prognathism has been segregating. Obviously, the presumed dominant gene is not fully penetrant in the heterozygous state. Pedigree analysis using the Elston-Stewart algorithm yields a maximum likelihood estimate (MLE) of p = 0.955 (SE 0.038) of the penetrance parameter.
Subject(s)
Prognathism/genetics , Europe , Female , Genes, Dominant , Heterozygote , History, 15th Century , History, 16th Century , History, 17th Century , History, 18th Century , History, 19th Century , History, 20th Century , Humans , Likelihood Functions , Male , Models, Genetic , Pedigree , Phenotype , Prognathism/historySubject(s)
Anodontia/history , Famous Persons , Prognathism/history , Anodontia/genetics , Austria , Female , France , History, 15th Century , Humans , Pedigree , Prognathism/geneticsABSTRACT
We report a three generation family with similar facial characteristics to those of the Royal Habsburgs, including mandibular prognathism, thickened lower lip, prominent, often misshapen nose, flat malar areas, and mildly everted lower eyelids. One child had craniosynostosis which may be part of the syndrome.
Subject(s)
Craniosynostoses/genetics , Famous Persons , Mandible/abnormalities , Medicine in the Arts , Prognathism/genetics , Adult , Child , Craniosynostoses/history , Facial Bones/abnormalities , Female , History, 15th Century , History, 16th Century , Humans , Male , Middle Aged , Prognathism/history , SpainABSTRACT
Nós descrevemos a ocorrência do prognatismo mandibular autossômico dominante característico dos Habsburgo na família imperial brasileira, baseados em evidência apresentada por V. Galippe em seu livro de 1905 entitulado "L' Herédité des Estigmates de Dégenerecences et les Familles Souveraines". Nós apresentamos um heredograma desde Dom Pedro II, que foi o último imperador do Brasil e era afetado, e Ernesto de ferro, que viveu no século XIV e que foi o primeiro Habsburgo documentado como afetado com o prognatismo mandibular
Subject(s)
Humans , History, Medieval , History, 15th Century , History, 18th Century , History, 19th Century , Famous Persons , Prognathism/genetics , Brazil , Prognathism/historySubject(s)
Famous Persons , Germany , History, 16th Century , Humans , Male , Mental Disorders/history , Prognathism/historySubject(s)
Prognathism/history , Germany , History, 16th Century , History, 17th Century , Humans , Male , Mandible/abnormalities , SpainSubject(s)
Cephalometry , Ethnicity/history , Paleodontology , Adult , England , Female , History, 20th Century , History, Ancient , Humans , Male , Prognathism/diagnosis , Prognathism/history , Radiography , Skull/diagnostic imagingSubject(s)
Famous Persons , Medicine in the Arts , Prognathism/history , Female , History, 15th Century , History, 16th Century , Humans , Male , Prognathism/geneticsSubject(s)
Prognathism/history , Austria , Famous Persons , Female , History, 15th Century , History, 16th Century , History, 17th Century , History, Medieval , Humans , Male , Mandible/surgery , Prognathism/surgery , SpainABSTRACT
From the 13th century untill well into the 20th, the Habsburgs were one of the great powers in Europe--for most of this time, the leading dynasty. To preserve the purity of the line, marriages between uncles and nieces, aunts and nephews, and cousins were commonplace. As a consequence, genetic complexities developed, and the famous prognathic "Habsburg jaw," among other noticeable traits, was passed down to succeeding generations. Never has a dynasty been so well documented in paintings, and their portraits provide an unusually complete series of medical illustrations that show the facial characteristics that marked the family in general. The observations are confirmed and extended by information from modern medical sources as well as from the medical records that date to the Habsburgs' own times.
Subject(s)
Famous Persons , Prognathism/history , Austria , Consanguinity , Female , Genealogy and Heraldry , History, 16th Century , History, 17th Century , History, 18th Century , History, 19th Century , Humans , Male , Prognathism/genetics , SpainABSTRACT
Report concerning roentgenographic examinations of an Egyptian mummy dating back to 900 B.C. from the "Museum für Völkerkunde Freiburg/Breisgau". The study was performed to detect funeral gifts which can be found otherwise only if the linnen bandage of the mummy is destroyed. Extraordinary findings were degenerative osteoarthritis of the spine and joints, pseudo-gout, marked caries of several teeth and signs for a healed occipital osteomyelitis. Suggestions are discussed about a particular compression of thorax and pelvis which is apparently due to the technique of bandaging. This was not observed in examinations of other mummies. Fractures of the first to third phalanges suggest forceful removal of precious rings. A circular-shaped opening in the parietal bone and a small radiodense foreign body which projects over the pharynx remain unexplained.
