1.
Nihon Naika Gakkai Zasshi
; 87(10): 2091-2, 1998 Oct 10.
Article
in Japanese
| MEDLINE
| ID: mdl-9867022
2.
Int J Clin Pharmacol Ther Toxicol
; 26(6): 297-9, 1988 Jun.
Article
in English
| MEDLINE
| ID: mdl-3410606
ABSTRACT
The pharmacokinetic data of methylepoxyproscillaridin (3'-methyl-4'-5'-epoxyproscillaridin) (P35) after 1 mg i.v. or oral administration in two different galenic preparations (hard and soft gelatin capsules) in randomized succession were studied in 9 healthy volunteers, showing a bioavailability of 88 +/- 10.5% (soft gelatin capsule) and 81 +/- 12% (hard gelatin capsule). The half-life of P35 was calculated to be 80 +/- 13.3 h.
