ABSTRACT
In recent years, the improvement in microbiological diagnostic methods has caused the spectrum of infectious agents causing male urethroadnexitis to expand considerably. In addition to the well-known urinogenic enterobacteriae and enterococci and the sexually transmitted gonococci and trichomonads, Chlamydia trachomatis and Ureaplasma urealyticum must now be considered particularly important etiologic agents that are sexually transmitted. Their cell biology and epidemiology, our diagnostic procedures, and the criteria of etiologic classification of male urethroadnexitis are described in detail. The recently developed quinolone derivates offer new and promising therapeutic perspectives.
Subject(s)
Balanitis/transmission , Prostatitis/transmission , Sexually Transmitted Diseases/transmission , Urethritis/transmission , Humans , Male , Microbiological TechniquesABSTRACT
One of the etiological agents of urethritis and prostatitis is Chlamydia trachomatis which reveals obligatory intracellular parasitism. Patient specimens (smears of the urethra, urine, first portion, expressed prostatic fluid, ejaculate) are centrifuged onto special cell cultures, so-called McCoy cells, and induce characteristic cytoplasmatic inclusions. Giemsa staining or DNA-binding fluorochromes (DAPI or Hoechst 33258) are suitable procedures to identify chlamydia inclusions. Serologic tests to establish infections due to Chlamydia trachomatis are only of limited diagnostic value.