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1.
J Diabetes Investig ; 12(7): 1301-1305, 2021 Jul.
Article in English | MEDLINE | ID: mdl-33179391

ABSTRACT

Type 2 diabetes mellitus patients are immunocompromised, particularly under poorly controlled conditions, and thereby they could develop rare inflammatory diseases, such as spontaneous discitis, pyogenic psoas abscess, spinal epidural abscess and bacterial meningitis. Herein we report a pyogenic psoas abscess on the dorsal side, and bacterial meningitis and spinal epidural abscess on the ventral side, both of which were induced by spontaneous discitis in a patient with poorly controlled type 2 diabetes mellitus. This case was very rare and interesting, because we successfully treated various infections with antibiotics over a long period of time, complicated by hyperglycemic crises, although the patient suffered severe bone destruction and required rehabilitation for a long time.


Subject(s)
Diabetes Mellitus, Type 2/microbiology , Discitis/microbiology , Epidural Abscess/microbiology , Meningitis, Bacterial/microbiology , Psoas Abscess/microbiology , Spinal Diseases/microbiology , Staphylococcal Infections/microbiology , Anti-Bacterial Agents/therapeutic use , Diabetes Mellitus, Type 2/blood , Discitis/pathology , Epidural Abscess/pathology , Female , Glycemic Control/adverse effects , Humans , Meningitis, Bacterial/pathology , Middle Aged , Psoas Abscess/pathology , Staphylococcal Infections/pathology
2.
Homo ; 71(4): 299-316, 2020 Nov 30.
Article in English | MEDLINE | ID: mdl-33147318

ABSTRACT

As part of a larger research project, 274 skeletons from three medieval Icelandic sites were evaluated for signs of infectious disease and 32 were found to have lesions at least consistent with a diagnosis of tuberculosis (TB): eight non-adults ranging in age from infancy to up to 17 years of age, and 24 adults. A higher proportion of individuals from Skeljastaðir and Keldudalur were affected than at Hofstaðir, an observation which may be compatible with Hofstaðir's higher status. A higher number of male skeletons overall (n. 17) than female skeletons (n. 8) exhibited pathological change. The sample is unique for its high numbers of well-preserved infants, and the appearance of TB in children is indicative of continual transmission in a community. The changes recorded in infant remains are marked by destruction and minimal periosteal new bone formation, while one adult skeleton exhibits the classic sign of Pott's disease. Other signs on the skeletons include evidence for past lymphadenitis and iliopsoas (cold) abscess. These cases indicate that TB was likely introduced to Iceland soon after the settlement period and became endemic in different regions from at least the late 10th - mid 13th centuries.


Subject(s)
Bone and Bones/pathology , Tuberculosis , Adolescent , Adult , Child , Endemic Diseases/history , History, Medieval , Humans , Iceland/ethnology , Infant , Middle Aged , Paleopathology , Psoas Abscess/history , Psoas Abscess/pathology , Tuberculosis/history , Tuberculosis/pathology , Young Adult
3.
Pan Afr Med J ; 36: 231, 2020.
Article in English | MEDLINE | ID: mdl-33708322

ABSTRACT

Malignant psoas syndrome (MPS) is very rare with poor prognosis, and usually occurs in patients with advanced and recurrent cancer. Authors report herein the case of a 48-year-old female with history of neoadjuvant chemotherapy has been performed before hysterectomy with bilateral adnexectomy and ovariectomy for ovarian adenocarcinoma. She presented 18 months posttreatment with MPS due to a psoas abscess mimicking metastasis confirmed on computed tomography guided fine needle aspiration cytology.


Subject(s)
Adenocarcinoma/pathology , Ovarian Neoplasms/pathology , Psoas Abscess/diagnosis , Adenocarcinoma/therapy , Biopsy, Fine-Needle , Female , Humans , Hysterectomy , Middle Aged , Neoadjuvant Therapy , Ovarian Neoplasms/therapy , Ovariectomy , Psoas Abscess/pathology , Tomography, X-Ray Computed
5.
J Med Case Rep ; 13(1): 253, 2019 Aug 15.
Article in English | MEDLINE | ID: mdl-31412911

ABSTRACT

BACKGROUND: Psoas or epidural abscesses are often accompanied by pyogenic spondylitis and require drainage. Posterolateral percutaneous endoscopic techniques are usually used for hernia discectomy, but this approach is also useful in some cases of psoas or lumbar ventral epidural abscess. We here report a case of psoas and epidural abscesses accompanied by pyogenic spondylitis that was successfully treated by percutaneous endoscopic drainage. CASE PRESENTATION: Our patient was a 57-year-old Japanese woman who had been receiving chemotherapy for inflammatory breast cancer and who became unable to walk due to lower back and left leg pain. She was transported as an emergency to another hospital. Magnetic resonance imaging revealed psoas and epidural abscesses accompanied by pyogenic spondylitis, and methicillin-resistant Staphylococcus aureus was detected in a blood culture. Drainage of the psoas abscess was performed under echo guidance, but was not effective, and she was transferred to our institution. We performed percutaneous endoscopic drainage for the psoas and epidural abscesses. Immediate pain relief was achieved and the inflammatory reaction subsided after 8 weeks of antibiotic therapy with daptomycin. CONCLUSIONS: Percutaneous endoscopy allowed us to approach the psoas and epidural abscesses directly, enabling the immediate drainage of the abscesses with less burden on the patient.


Subject(s)
Drainage/methods , Epidural Abscess/surgery , Psoas Abscess/surgery , Endoscopy/methods , Epidural Abscess/complications , Epidural Abscess/diagnostic imaging , Epidural Abscess/pathology , Female , Humans , Lumbar Vertebrae/diagnostic imaging , Lumbar Vertebrae/pathology , Magnetic Resonance Imaging , Methicillin-Resistant Staphylococcus aureus/isolation & purification , Middle Aged , Psoas Abscess/complications , Psoas Abscess/diagnostic imaging , Psoas Abscess/pathology , Spondylitis/complications , Staphylococcal Infections/blood , Staphylococcal Infections/complications
7.
J Med Case Rep ; 13(1): 47, 2019 Mar 01.
Article in English | MEDLINE | ID: mdl-30819241

ABSTRACT

BACKGROUND: Parvimonas micra, a Gram-positive anaerobic coccus, is a rare pathogen for psoas abscess. We describe a case of a patient with iliopsoas abscess caused by P. micra. CASE PRESENTATION: An 81-year-old Asian man presented to our department with complaints of fever since the preceding day. Abdominal computed tomography revealed the presence of a low-density mass in the right iliopsoas muscle indicative of a psoas abscess. Computed tomography-guided percutaneous drainage of the psoas abscess was performed. Results of organism cultures of the abscess and blood were positive for P. micra. However, our patient had no known primary focus of infection. On the basis of these findings, a primary psoas abscess caused by P. micra was diagnosed, and treatment with ampicillin/sulbactam 1.5 g, administered intravenously every 8 h, was initiated. By day 7, the patient's white blood cell count normalized. By day 20, his C-reactive protein level was decreased to 0.35 mg/dl. CONCLUSION: Iliopsoas abscesses caused by anaerobic bacteria are relatively rare, and iliopsoas abscesses caused by P. micra are especially rare. Our patient's case revealed that P. micra can cause iliopsoas abscess. Therefore, clinicians should be aware of the possibility that P. micra may cause iliopsoas abscess.


Subject(s)
Anti-Bacterial Agents/therapeutic use , Drainage/methods , Fever/microbiology , Gram-Positive Bacterial Infections/pathology , Psoas Abscess/pathology , Administration, Intravenous , Aged, 80 and over , C-Reactive Protein/analysis , Gram-Positive Bacterial Infections/microbiology , Gram-Positive Bacterial Infections/therapy , Humans , Male , Psoas Abscess/diagnostic imaging , Psoas Abscess/microbiology , Psoas Abscess/therapy , Tomography, X-Ray Computed , Treatment Outcome , Ultrasonography, Interventional
9.
World Neurosurg ; 120: 43-46, 2018 Dec.
Article in English | MEDLINE | ID: mdl-30149157

ABSTRACT

BACKGROUND: Sequestered disc fragments may present as a lesion with peripheral enhancement on magnetic resonance imaging. When located in the psoas muscle compartment, this finding could mimic an abscess. CASE DESCRIPTION: We describe a case of a 52-year-old man who returned from Togo after 2 years of living in precarious conditions. He was afebrile and complaining of lumbar back pain. The magnetic resonance imaging showed L3 and L4 vertebral body enhancement with bilateral psoas lesions in continuity with the disc space, suggesting spondylodiscitis with a differential diagnosis of inflammatory herniated disc. A computed tomography-guided biopsy of the right psoas lesion was performed to rule out spondylodiscitis. Histology was compatible with extruded disc material. CONCLUSION: Herniated disc fragments should be considered as a differential diagnosis of psoas abscesses. Coronal plane images may show the continuity of bilateral herniated disc fragments, mimicking psoas abscesses.


Subject(s)
Intervertebral Disc Degeneration/diagnostic imaging , Intervertebral Disc Degeneration/pathology , Intervertebral Disc Displacement/diagnostic imaging , Intervertebral Disc Displacement/pathology , Psoas Abscess/diagnostic imaging , Psoas Abscess/pathology , Diagnosis, Differential , Discitis/diagnosis , Humans , Intervertebral Disc Degeneration/surgery , Intervertebral Disc Displacement/surgery , Male , Middle Aged , Psoas Abscess/surgery
11.
Medicine (Baltimore) ; 96(19): e6837, 2017 May.
Article in English | MEDLINE | ID: mdl-28489769

ABSTRACT

RATIONALE: Psoas abscesses generally arise from a contiguous intra-abdominal or pelvic infectious process or hematogenous spreading of bacteria. The serum ß-human chorionic gonadotropin has been used to detect normal or ectopic pregnancy. It also can be utilized in following up carcinomas. PATIENT CONCERNS: Here, we reported a case of a 47-year-old woman who presented with a left psoas mass presumptively diagnosed as an abscess secondary to lumbar tuberculosis In addition, the patient had abnormal increase of ß-human chorionic gonadotropin. The computed tomography (CT) scan and magnetic resonance imaging (MRI) showed that the 5th lumbar vertebral infection or tuberculosis with left psoas abscess. CT-guided percutaneous biopsy, surgical exploration and biopsy, and F-FDG (fluorodeoxyglucose) positron emission tomography-CT (PET-CT) were used to make a definite diagnosis. The sigmoidoscopy and biopsy were used to further diagnose. DIAGNOSES: The biopsy of left psoas demonstrated metastatic or infiltrating poorly differentiated carcinoma with secretion of ß-human chorionic gonadotropin. The subsequent pathological examination of neoplasm showed the same pathologic morphology. INTERVENTIONS: Appropriate treatment of infected retroperitoneal mass, systematic chemotherapy and cancer biotherapy for metastatic poorly differentiated carcinoma were taken. OUTCOMES: Interventions provided little help until the patient died of secondary infection and multiple organ failure. LESSONS: This case represents an extremely unusual clinical presentation of metastatic poorly differentiated carcinoma with secretion of ß-human chorionic gonadotropin presenting as a psoas abscess. Physicians also need to sharpen their awareness of the potential malignant carcinomas mimicking psoas abscess.


Subject(s)
Carcinoma/diagnosis , Carcinoma/metabolism , Chorionic Gonadotropin, beta Subunit, Human/metabolism , Psoas Abscess/diagnosis , Retroperitoneal Neoplasms/diagnosis , Retroperitoneal Neoplasms/metabolism , Carcinoma/drug therapy , Carcinoma/pathology , Diagnosis, Differential , Female , Humans , Middle Aged , Psoas Abscess/etiology , Psoas Abscess/pathology , Retroperitoneal Neoplasms/drug therapy , Retroperitoneal Neoplasms/pathology , Retroperitoneal Space/diagnostic imaging , Retroperitoneal Space/pathology , Retroperitoneal Space/surgery
14.
Pan Afr Med J ; 28: 280, 2017.
Article in French | MEDLINE | ID: mdl-30402201

ABSTRACT

Psoas abscesses account for 5-10% of abdominal suppurations. They can be primary or secondary. Primary polymicrobic abscesses of the psoas muscle including, in particular, tuberculous abscesses and pyogenic abscesses, have never been reported in the literature. We report the case of a 35-year old patient, with no particular past medical history, admitted with pain in the right lumbar fossa associated with a fever of 40°C. Onset of symptoms had occurred 5 months before, but without fever. Abdominal CT scan showed an abscess of the right external transverse and oblique psoas muscles extended to the retroperitoneum and infiltrating the thoracoabdominal wall. Cytobacteriological examination of pus showed fast-growth monomorphic wild-type Escherichia coli strains. Systematically performed Real-time PCR test for the detection of Complex Mycobaterium tuberculosis was positive while direct examination after Ziehl-nelseen staining was negative. The culture on a solid Lowenstein Jensen medium was positive after one-month of incubation. The outcome of our patient was favorable under antibacillar quadritherapy and ceftriaxone. This study highlights that a tuberculous origin should be systematically suspected in patients living in endemic areas with chronic, recurrent psoas abscess not responding to antibiotics.


Subject(s)
Anti-Bacterial Agents/administration & dosage , Psoas Abscess/diagnosis , Tuberculosis/diagnosis , Adult , Antitubercular Agents/administration & dosage , Escherichia coli/isolation & purification , Escherichia coli Infections/diagnosis , Escherichia coli Infections/drug therapy , Escherichia coli Infections/pathology , Humans , Male , Mycobacterium tuberculosis/isolation & purification , Psoas Abscess/drug therapy , Psoas Abscess/pathology , Real-Time Polymerase Chain Reaction , Suppuration/diagnosis , Suppuration/drug therapy , Suppuration/pathology , Tomography, X-Ray Computed/methods , Tuberculosis/drug therapy , Tuberculosis/pathology
17.
Intern Med ; 54(20): 2589-93, 2015.
Article in English | MEDLINE | ID: mdl-26466693

ABSTRACT

Objective Patients diagnosed with psoas abscess have a high mortality rate. The major cause of its poor prognosis is delayed treatment. Therefore, making a correct diagnosis rapidly is important. Both computed tomography (CT) and magnetic resonance imaging (MRI) are considered to be the gold standards as imaging modalities that have a high sensitivity for detecting psoas abscess. There have been few reports regarding the limitations of these methods, but psoas abscess in its early stage may go undetected by CT and MRI. Methods Detection of psoas abscess by CT and MRI was investigated in the present study through a retrospective review of 15 patients in whom psoas abscess was diagnosed during a course of ten years at our hospital. Results In all patients, psoas abscess was diagnosed by at least a plain CT, enhanced CT, and/or plain MRI. The interval between the onset of symptoms and diagnosis was 20.9±17.9 days (mean ± standard deviation). In three patients, repeat imaging identified a psoas abscess, whereas initial imaging failed to detect it. The overall sensitivity of plain CT, enhanced CT, and plain MRI for psoas abscess was 78%, 86%, and 88%, respectively. From six days after the onset of symptoms, the sensitivity of each modality was 100%, while the sensitivity from day one to five days was only 33%, 50%, and 50%, respectively. Conclusion Although CT and MRI are considered to be gold standard modalities for diagnosing psoas abscess, both methods can fail to notice this condition in its early stage.


Subject(s)
Magnetic Resonance Imaging , Psoas Abscess/diagnosis , Tomography, X-Ray Computed , Early Diagnosis , Female , Humans , Japan , Male , Middle Aged , Prognosis , Psoas Abscess/pathology , Psoas Abscess/surgery , Reproducibility of Results , Retrospective Studies , Sensitivity and Specificity
18.
Intern Med ; 54(13): 1653-6, 2015.
Article in English | MEDLINE | ID: mdl-26134200

ABSTRACT

A 55-year-old man was diagnosed with remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome. Contrast-enhanced computed tomography for cancer screening showed a mass with low-density centers with an enhanced rim in the left iliopsoas muscle. We suspected an iliopsoas abscess and performed computed-tomography-guided puncture of the mass. Both Gram staining and the culture of the fluid were negative. We diagnosed the patient with RS3PE syndrome with iliopsoas bursitis and administered low-dose corticosteroids without antibiotics. The symptoms, including left hip pain, quickly disappeared following treatment. Clinicians should be aware that iliopsoas bursitis may resemble an iliopsoas abscess. As a result, it is important to make an accurate differential diagnosis.


Subject(s)
Anti-Inflammatory Agents/therapeutic use , Bursitis/diagnosis , Prednisolone/therapeutic use , Psoas Abscess/diagnosis , Tomography, X-Ray Computed , Bursitis/complications , Bursitis/drug therapy , Bursitis/pathology , Contrast Media/administration & dosage , Diagnosis, Differential , Edema/etiology , Humans , Male , Middle Aged , Psoas Abscess/complications , Psoas Abscess/drug therapy , Psoas Abscess/pathology , Punctures/methods , Syndrome , Synovitis/etiology , Tomography, X-Ray Computed/methods
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