Dental pathologies in tumor patients with bone metastases or multiple myeloma scheduled for antiresorptive therapy.

Background: Medication-related osteonecrosis of the jaw (MRONJ) is a potentially severe complication of mainly antiresorptive drugs. We evaluated the frequency of dentoalveolar pathologies in patients scheduled for antiresorptive therapy in a 'real-world' setting, also including patients with poor oral health potentially requiring tooth extractions and/or other dentoalveolar surgery. This approach is in contrast to the setting of recent randomized trials with restrictive exclusion criteria. Patients & methods: We prospectively included patients suffering from solid tumors with osseous metastases or multiple myeloma. Screening for dentoalveolar pathologies was done prior to initiation of antiresorptive therapy at the specialized MRONJ clinic of the University Hospital for Cranio-Maxillofacial and Oral Surgery, Innsbruck, Austria. Results: 119 subjects could be included. In 76 patients (63.9%), a dental focus was revealed including deep caries (24.4% of patients), chronic apical periodontitis (26.9%), periodontal disease (45.8%), root remnants (16%), jaw cysts (2.5%), partially impacted teeth (5.0%) and peri-implantitis (5.0%). Conclusion: Considering the high number of dentoalveolar pathologies (63.9%), systematic dental focus screening prior to initiation of antiresorptive therapy is of utmost importance to lower the risk for MRONJ.

Comparing third molar root development staging in panoramic radiography, extracted teeth, and cone beam computed tomography.

This study aimed at performing and comparing third molar development staging in extracted teeth (EX), panoramic radiography (PAN), and cone beam computed tomography (CBCT). Extracted third molars (n = 158, 95 maxillary, 63 mandibular) from 102 patients (36 males, 66 females) having at least one preoperative PAN and one CBCT were studied. Third molar development staging was performed in PAN, EX, and CBCT using Gleiser et al. (1955) technique modified by Köhler et al (1994). A polytomous logistic regression model was used to compare the staging performed in EX and CBCT with the gold standard staging in PAN. The pair-wise stage comparisons between third molar modalities revealed 63.3% equal staging. In all other comparisons, a maximum difference of one stage was detected. No statistically significant differences between the three staging modalities were detected (p = 0.26). The comparison between EX and PAN staging revealed higher similarity (p = 0.98 in stages 5-10) than the comparison between CBCT and PAN staging (p = 0.81 in stages 5, 7, and 9, and p = 0.80 in stages 6, 8, and 10). The studied third molar staging technique originally designed in PAN can be applied for third molar staging EX and in CBCT.

Brightness and contrast adjustments influence the radiographic detection of soft tissue calcification.

OBJECTIVE: To assess the influence of subjective enhancement of brightness and contrast of digital panoramic radiographs on the detection of soft tissue calcifications. MATERIALS AND METHODS: In this observational study, 500 digital panoramic radiographs were evaluated by two examiners in consensus, who scored the images for the presence of calcifications for each right and left side of the image. After 30 days, all images were revaluated under subjective manipulation of digital brightness and contrast. Calcifications were classified based on the diagnostic hypothesis: sialolith, tonsillolith, calcified atheroma, phlebolith, rhinolith, maxillary sinus antrolith, synovial chondromatosis, lymph node calcification, stylohyoid ligament, triticeous cartilage, or/and upper horn of thyroid cartilage calcification. For intra-examiner agreement, 20% of the sample was reevaluated. The Kappa test and McNemar test were used (α = 0.05). RESULTS: In original images, calcifications were observed in 44.2% of the patients, and in enhanced images, this number was 70.8%. Many calcifications were detected only in enhanced images, mainly in the diagnostic hypotheses of calcified atheroma and stylohyoid ligament. Intra-examiner agreement was excellent for the detection of soft tissue calcifications (0.82) and for the classification (0.81). CONCLUSION: Subjective enhancement of brightness and contrast alters the detection of soft tissue calcifications in digital panoramic radiograph.

OSL dosimeters for dental panoramic radiography.

The aim of the present work is to determine dosimetric characteristics of commercial optically stimulated luminescence dosimeter (OSLD) to estimate equivalent dose in the patient undergoing panoramic radiography procedure. Digital panoramic unit "Instrumentarium OP200D" was used. OSL dosimeters were optically bleached before any exposure procedure. InLight™ OSL nanodosimeters were placed on the thyroid surface between the head and neck. The exposure parameters for all measurements was standard value consisted in 66 kV, 5 mA, and 14.1 s. Standard size field of view (FOV) scanning mode was used. Dosimeters were calibrated for the air kerma. Reported male adult equivalent doses from 21 to 45 µSv for each scanning for standard size field of view (FOV). Meanwhile reported female adult equivalent doses from 28 to 75 µSv for standard size field of view (FOV) considering all heights. The lowest equivalent dose (21 µSv) was observed in the male thyroid gland surface (S) position for medium height. The highest equivalent dose (75 µSv) was for female small height in the right parotid surface (R) position. In conclusion, the results demonstrate that OSL dosimeters are appropriate in vivo dosimetry system for dental panoramic dose measurements.

Low reproducibility between oral radiologists and general dentists with regards to radiographic diagnosis of caries.

AIM: Early clinical and radiological diagnosis of dental caries is one of the fundamental objectives of clinical dentistry because of the high frequency of the disease and severe complications if caries remains untreated, especially among the elderly and patients with immunodeficiency. Dental panoramic tomography (DPT) is a common radiographic method for evaluating dentition when indicated, especially in an adult population. The aim of this study was to assess the reproducibility of diagnosis between specialists in oral radiology and general dentists with regards to caries lesions based on DPTs of adults. MATERIAL AND METHODS: One-hundred DPTs taken from adult patients (average age 35) and then analyzed and reported on by 42 general dentists were then analyzed independently by two specialists in oral radiology with respect to caries lesions in the premolar and molar areas using radiographic criteria established for caries diagnosis. The general dentists versus oral radiologists were not calibrated before. Level of agreement between specialists and general dentists was measured using Cohen's kappa. RESULTS: Comparison between observations of general dentists and specialists in oral radiology showed that 61% of the caries lesions on proximal surfaces of premolars and molars observed by specialists went unobserved by general dentists. Cohen's kappa value for specialists was 0.85 (p < .001) and for each specialist and general dentists 0.48 (p < .001) and 0.44 (p < .001). CONCLUSIONS: The reproducibility between specialists in oral radiology and general dentists for detecting caries in DPTs was low.

Large peripheral ossifying fibroma: clinical, histological, and immunohistochemistry aspects. A case report / Gran fibroma osificante periférico: aspectos clínicos, histológicos e inmunohistoquímicos. Presentación de un caso

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[Panoramic radiographs in dental diagnostics]. / Panoramische röntgenopnamen in de tandheelkundige diagnostiek.

Panoramic radiographs are frequently used in dental practice in addition to bitewing radiographs and periapical radiographs. The way a panoramic photograph is created is different from that of a projection image, such as bitewing and periapical radiographs. As a result, the sharpness of detail is much less, and overlap of structures occurs in different areas of the image. Consequently the diagnostic utility is limited to the recognition of anomalies for which small details play a lesser role. The advantage of a panoramic radiograph is that structures over a large area are shown in their relative location. Because of the lower resolution and the higher dose of radiation to the patient compared with a series of intraoral images, the panoramic radiograph is not indicated during a periodic check-up. If clinical inspection indicates a need for it and as a supplement to an intraoral radiograph, a panoramic radiograph can, however, be appropriate in cases of abnormalities that extend over a larger area, such as tumours and developmental disorders.

Are children's dental panoramic tomographs and lateral cephalometric radiographs sufficiently optimized?

OBJECTIVES: Children are especially vulnerable to harmful effects of ionizing radiation. Cutting down the dimensions of the X-ray beam is the most effective way to reduce the patient dose. We evaluated the appropriateness of field-size in the most frequent radiographs, dental panoramic tomographs (DPTs) and lateral cephalometric radiographs (LCRs) among 7- to 12-year-olds. MATERIALS AND METHODS: The image field-size of 241 DPTs and 118 LCRs was analysed. The image field was considered appropriate when it did not include anatomic structures beyond the area of clinical interest. The image field was compared with factors such as the age of the patient, the radiographic equipment used and the programme selected. Moreover, we assessed the use of thyroid shield in LCR. RESULTS: The field-size was too large in 70% of the DPTs horizontally and in 96% vertically. None of the DPTs were segmented. Every LCR showed appropriate limitation anteriorly, but the image field was too large in 54% posteriorly, in 86% superiorly, and in 76% inferiorly. A thyroid shield had been used in only 71% of cases. CONCLUSION: Most DPTs and LCRs had been performed sub-optimally. An abundancy of DPTs had been taken using an adult programme, and the field-size had not been sufficiently adjusted in LCRs, possibly for technical reasons. To facilitate adherence to radiological best practice the equipment used for DPTs and LCRs should facilitate the adjustment of field-size in both the vertical and horizontal planes. In addition, those involved in taking radiographs should maintain their skills through regular update courses.

Optimization of exposure in panoramic radiography while maintaining image quality using adaptive filtering.

Objective The purpose of the present study was to investigate the potential of using advanced external adaptive image processing for maintaining image quality while reducing exposure in dental panoramic storage phosphor plate (SPP) radiography. Materials and methods Thirty-seven SPP radiographs of a skull phantom were acquired using a Scanora panoramic X-ray machine with various tube load, tube voltage, SPP sensitivity and filtration settings. The radiographs were processed using General Operator Processor (GOP) technology. Fifteen dentists, all within the dental radiology field, compared the structural image quality of each radiograph with a reference image on a 5-point rating scale in a visual grading characteristics (VGC) study. The reference image was acquired with the acquisition parameters commonly used in daily operation (70 kVp, 150 mAs and sensitivity class 200) and processed using the standard process parameters supplied by the modality vendor. Results All GOP-processed images with similar (or higher) dose as the reference image resulted in higher image quality than the reference. All GOP-processed images with similar image quality as the reference image were acquired at a lower dose than the reference. This indicates that the external image processing improved the image quality compared with the standard processing. Regarding acquisition parameters, no strong dependency of the image quality on the radiation quality was seen and the image quality was mainly affected by the dose. Conclusions The present study indicates that advanced external adaptive image processing may be beneficial in panoramic radiography for increasing the image quality of SPP radiographs or for reducing the exposure while maintaining image quality.

Quality assessment of orthodontic radiography in children.

OBJECTIVES: Numbers of dental panoramic tomographs (DPTs) and lateral cephalometric radiographs (LCRs) outweigh other radiographic examinations in 7- to 12-year-old Finns. Orthodontists and general practitioners (GPs) involved in orthodontics hold therefore the highest responsibility of the exposure of children to ionising radiation with its risks. Against this background, lack of reports on the quality of orthodontic radiography is surprising. The purpose of our study was to shed some light and draw the awareness of the orthodontic community on the subject by analyzing the quality of orthodontic radiography in Oral Healthcare Department of City of Helsinki, in the capital of Finland. MATERIALS AND METHODS: We analyzed randomly selected 241 patient files with DPTs and 118 patient files with LCRs of 7- to 12-year-olds for the indications of radiography, quality of referrals, status of interpretation, and number of failed radiographs. RESULTS: The majority of DPTs (95%) and all LCRs had been ordered for orthodontic reasons. Of the DPTs, 60% were ordered by GPs, and of the LCRs, 64% by orthodontists. The referrals were adequate for most DPTs (78%) and LCRs (73%), orthodontists being responsible for the majority of inadequate referrals. Of the DPTs, 80% had been interpreted. Of the LCRs, 65% lacked interpretation, but 67% had been analysed cephalometrically. Failed radiographs, leading to repeated exposure, were found in 2-3%. CONCLUSION: The quality assessment revealed that orthodontic radiography may not completely fulfill the criteria of good practice. Our results stress further need of continuing education in radiation protection among both orthodontists and GPs involved in orthodontics.

Accuracy of linear measurements using cone beam computed tomography and panoramic radiography in dental implant treatment planning.

PURPOSE: The aim of this study was to investigate the accuracy of linear measurements from cone beam computed tomography (CBCT) images and digital panoramic radiographs at various implant sites. MATERIALS AND METHODS: Fifty implant sites from six skulls were marked with gutta-percha and subjected to CBCT with five different voxel protocols: 0.125 mm, 0.160 mm, and 0.250 mm with the 3D Accuitomo 170 CBCT machine and 0.200 mm and 0.300 mm with the CS 9500 CBCT machine. Images were also taken with the CS 9000 panoramic machine with three protocols: normal head, chin-up, and chin-down positions. Electronic linear measurement of bone height using the corresponding machine's software was recorded by two observers. Physical measurement using a digital caliper with ± 0.02-mm accuracy was directly recorded at the corresponding regions as the gold standard. All image measurements were compared with the physical measurements. The paired sample correlations for physical measurement, mean difference, standard deviation, absolute error, absolute percentage error, and inter- and intraobserver reliability were calculated. RESULTS: Intraobserver and interobserver reliability was more than 0.99. Paired sample correlation between all image measurements and physical measurements was considered statistically significant at P < .05. All image measurements were underestimated by less than 2 mm, except for the chin-down position of the maxilla in the panoramic radiograph. The absolute error and absolute percentage error in the mandible were less than those in the maxilla, and values obtained with CBCT were less than those from panoramic radiographs. CONCLUSION: CBCT images using the 3D Accuitomo 170 and CS 9500 machines and digital panoramic radiographs via a picture archiving and communication system are sufficiently accurate for vertical linear measurements in dental implant treatment planning.

Establishment of diagnostic reference levels for dental panoramic radiography in Greece.

The purpose of the present study was to present the national diagnostic reference levels (DRL) established for panoramic dental examinations in Greece. The establishment of DRL, as a tool for the optimisation of radiological procedures, is a requirement of national regulations. Measurements performed by the Greek Atomic Energy Commission on 90 panoramic systems have been used for the derivation of DRL values. DRL values have been proposed for exposure settings of different patient types (child, small adult and standard adult), both for film and digital imaging. The DRLs for different patient types are grouped in three categories: children, small adults (corresponding to female) and average adults (corresponding to male). Proposed DRLs for these groups are 2.2, 3.3 and 4.1 mGy, respectively. In order to investigate the correlation of DRLs with the available imaging modalities (CR, DR and film), this parameter was taken into account. DR imaging DRL is the lowest at 3.5 mGy, CR imaging the highest at 4.2 mGy and film imaging at 3.7 mGy. In order to facilitate comparison with other studies, kerma-width product values were calculated from Ki, air and field size.

Digital panoramic radiography for diagnosis of the temporomandibular joint: CBCT as the gold standard.

Three-dimensional imaging modalities have been reported to be more accurate than panoramic radiographs (PR) for the assessment of bone components of the temporomandibular joint (TMJ). No exact prior information is available that demonstrates which specific limitations occur in terms of TMJ diagnosis when using PR for this purpose. This study aimed to assess the clinical validity of digital panoramic radiography (DPR) when diagnosing morphological disorders of the TMJ using cone-beam computed tomography (CBCT) images as the gold standard. A sample composed of TMJ images (N = 848), including 212 DPR and 212 CBCT images obtained from the same patient, was used to assess any morphological changes in the TMJ. Four appraisers diagnosed all of the DPR images, whereas the CBCT images were used to establish the gold standard. The reliability of each appraiser's response pattern was analyzed using the Kappa test (κ), and diagnostic tests were performed to assess each appraiser's performance using a significance level setting of 5% (α = 0.05). Reliability of each appraiser's response pattern compared to the gold standard ranged from a slight-to-moderate agreement (0.18 ≤ κ ≤ 0.45); and among the different appraisers, the response pattern showed a fair agreement (0.22 ≤ κ ≤ 0.39). Diagnostic tests showed a wide range among the different possible morphological changes diagnosed. DPR does not have validity when diagnosing morphological changes in the TMJ; it underestimates the radiological findings with higher prevalence, and thus, it cannot be used effectively as a diagnostic tool for bone components within this region.

Impact of malpositioning on panoramic radiography in implant dentistry.

OBJECTIVES: The widely used panoramic radiography as a special kind of tomography underlies intrinsic procedural restrictions such as poor definition, inconsistent magnification, geometric distortion and spatial depositioning of objects situated outside the focal trough. This results in a non-anatomic display of the radiographed anatomic structures. Individual mandibular angle and width of the jaws, adjustment of the focal trough, jaw incongruence as well as patient positioning increase the inconsistency in display of the radiographed objects. This study precisely evaluated the quantitative impact of object malpositioning on the display in panoramic radiography. MATERIALS AND METHODS: A special dental implant model was highly accurate three dimensionally malpositioned and panoramic radiographs were taken. Automated image analysis was performed to exclude subjective assessment error. RESULTS: Precise and retraceable object deposition of up to 5 mm or 5° resulted in relevant deposition of objects and significant changes in object size and inter-object distances in the panoramic image. Unidirectional malpositioning lead to multiple errors in display. CONCLUSIONS: The extent of malpositioning-related display errors additionally to the known physicotechnical insufficiencies of the panoramic radiography demonstrates its limitations in precisely interpreting spatial relationships. CLINICAL RELEVANCE: Measurements within the panoramic radiography must not claim reliability. For a single object securely positioned in the focal trough and perpendicular to the central X-ray beam, measurements may be trustworthy on clinical scale. Once sterical relationships to other structures are evaluated, reliability must be questioned.

Efficacy of CBCT for assessment of impacted mandibular third molars: a review - based on a hierarchical model of evidence.

A radiographic examination of mandibular third molars is meant to support the surgeon in establishing a treatment plan. For years panoramic (PAN) imaging has been the first choice method; however, where an overprojection is observed between the third molar and the mandibular canal and when specific signs suggest a close contact between the molar and the canal, CBCT may be indicated. The present review provides an evaluation of the efficacy of CBCT for assessment of mandibular third molars using a six-tiered hierarchical model by Fryback and Thornbury in 1991. Levels 1-3 include studies on low evidence levels mainly regarding the technical capabilities of a radiographic method and the diagnostic accuracy of the related images. Levels 4-6 include studies on a higher level of evidence and assess the diagnostic impact of a radiographic method on the treatment of the patient in addition to the outcome for the patient and society including cost calculations. Only very few high-evidence studies on the efficacy of CBCT for radiographic examination of mandibular third molars exist and, in conclusion, periapical or PAN examination is sufficient in most cases before removal of mandibular third molars. However, CBCT may be suggested when one or more signs for a close contact between the tooth and the canal are present in the two-dimensional image-if it is believed that CBCT will change the treatment or the treatment outcome for the patient. Further research on high-evidence levels is needed.

Panoral dose assessment: a comparative report of methodologies.

National guidance from the Institute of Physics and Engineering in Medicine (IPEM Report 91) currently recommends that the patient dose for a panoral X-ray unit is measured as dose area product (DAP) replacing dose width product described in earlier guidance. An investigation identifying different methods available to carry out this measurement has been undertaken and errors in the methodologies analysed. It has been shown that there may be up to a 30 % variation in DAP measurement between methods. This paper recommends that where possible a DAP meter is used to measure the dose-area product from a panoral X-ray unit to give a direct DAP measurement. However, by using a solid-state dose measurement and film/ruler to calculate DAP the authors have established a conversion factor of 1.4. It is strongly recommended that wherever a DAP value is quoted the methodology used to obtain that value is also reported.

Digital panoramic radiography for diagnosis of the temporomandibular joint: CBCT as the gold standard

Three-dimensional imaging modalities have been reported to be more accurate than panoramic radiographs (PR) for the assessment of bone components of the temporomandibular joint (TMJ). No exact prior information is available that demonstrates which specific limitations occur in terms of TMJ diagnosis when using PR for this purpose. This study aimed to assess the clinical validity of digital panoramic radiography (DPR) when diagnosing morphological disorders of the TMJ using cone-beam computed tomography (CBCT) images as the gold standard. A sample composed of TMJ images (N = 848), including 212 DPR and 212 CBCT images obtained from the same patient, was used to assess any morphological changes in the TMJ. Four appraisers diagnosed all of the DPR images, whereas the CBCT images were used to establish the gold standard. The reliability of each appraiser’s response pattern was analyzed using the Kappa test (κ), and diagnostic tests were performed to assess each appraiser’s performance using a significance level setting of 5% (α = 0.05). Reliability of each appraiser’s response pattern compared to the gold standard ranged from a slight-to-moderate agreement (0.18 ≤ κ ≤ 0.45); and among the different appraisers, the response pattern showed a fair agreement (0.22 ≤ κ ≤ 0.39). Diagnostic tests showed a wide range among the different possible morphological changes diagnosed. DPR does not have validity when diagnosing morphological changes in the TMJ; it underestimates the radiological findings with higher prevalence, and thus, it cannot be used effectively as a diagnostic tool for bone components within this region.

Diagnóstico ortodôntico sem as radiografias periapicais de todos os dentes: cuidado, você pode se surpreender / Orthodontic diagnosis without periapical radiograph of all teeth: be careful, you might be surprised

Objetivo: a proposta do presente artigo foi relatar um caso clínico onde, ao serem analisados os detalhes anatômicos na radiografia panorâmica de um paciente previamente ao início do tratamento ortodôntico, não foi detectada a presença de dente extranumerário na região apical do primeiro molar superior esquerdo. Resultado: apesar da presença desse elemento extra, não houve a necessidade de removê-lo para a realização do tratamento ortodôntico, entretanto, poderia em uma outra situação clínica comprometer o bom andamento e sucesso do tratamento. Conclusão: dessa forma, conclui-se com a descrição desse caso clínico que a radiografia panorâmica não substitui o exame periapical no planejamento ortodôntico pois são complementares. Radiografias periapicais apenas dos dentes anteriores poderiam ser insuficientes para o diagnóstico e prevenção dos riscos da terapia ortodôntica.

Desarrollo tardío de múltiples dientes supernumerarios en una paciente con miastenia gravis juvenil tratada con azatioprina / Delayed development of multiple supernumerary teeth in a patient with juvenile myasthenia gravis treated with azathioprine

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Quality assurance tests for digital radiography in general dental practice.

UNLABELLED: Quality assurance (QA) is essential in dental radiography. Digital radiography is becoming more common in dentistry, so it is important that appropriate QA tests are carried out on the digital equipment, including the viewing monitor. The aim of this article is to outline the tests that can be carried out in dental practice. CLINICAL RELEVANCE: Quality assurance for digital equipment is important to ensure consistently high quality images are produced.