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1.
J. optom. (Internet) ; 17(3): [100505], jul.-sept2024. tab, graf
Article in English | IBECS | ID: ibc-231869

ABSTRACT

Purpose: This study explored whether retinoscopy (RET) provides comparable results of relative peripheral refraction (RPR) to open–field autorefractometry (AR) in myopic subjects.Methods: Peripheral refraction was measured in 20 myopic and 20 control adult subjects. Both central and peripheral refraction (20° nasal and temporal eccentricity) were measured using RET and open-field AR. Differences in the median central spherical equivalent (SE), median RPR, and median J45/J180 power vectors between the RET and AR techniques were analyzed. Moreover, Bland – Altman plots were used to assess the agreement between RET and AR methods for RPR measurements in MG. Results: For MG, the median RPR values were positive (hyperopic shift), and no significant differences were observed between the RET and AR techniques with respect to RPR measurement. In addition, we did not observe any significant differences in the RPR values between the nasal and temporal eccentricities for either the RET or AR technique for myopic subjects. There was also a significant correlation and agreement between the RET and AR technique for RPR measurements. With respect to central refraction, the median SE was slightly more positive for the RET than for the AR technique. Inside the CG, we also found significant correlation between the RET and AR technique for RPR measurements, and we observed a myopic shift in peripheral eccentricities. Conclusion: Our results show that retinoscopy may be a useful tool for objective measurements of RPR in myopic subjects and may be used interchangeably with the open-field AR method in everyday clinical practice. (AU)


Subject(s)
Humans , Retinoscopy , Myopia , Refraction, Ocular , Vision, Ocular , Vision, Binocular , Ophthalmologists
3.
Zhonghua Yan Ke Za Zhi ; 60(6): 490-493, 2024 Jun 11.
Article in Chinese | MEDLINE | ID: mdl-38825948

ABSTRACT

Multifocal intraocular lenses (MIOLs) have demonstrated efficacy and safety in adult cataract surgery, yet they encounter many challenges in pediatric applications. This article elaborates on the difficulties in biometric measurements in children, the unpredictability of postoperative refraction outcomes, the lack of long-term spectacle independence in children with MIOLs, the absence of significant advantages in correcting childhood amblyopia, and the potential increase in the rate of secondary surgeries. Due to the insufficient clinical evidence supporting the use of MIOLs in children at present, it is proposed that MIOLs be cautiously applied to children with congenital cataracts in clinical practice. Further research in this area is encouraged.


Subject(s)
Cataract Extraction , Cataract , Lens Implantation, Intraocular , Humans , Cataract/congenital , Cataract/therapy , Child , Lens Implantation, Intraocular/methods , Cataract Extraction/methods , Lenses, Intraocular , Multifocal Intraocular Lenses , Refraction, Ocular , Amblyopia , Visual Acuity
4.
Zhonghua Yan Ke Za Zhi ; 60(6): 541-546, 2024 Jun 11.
Article in Chinese | MEDLINE | ID: mdl-38825954

ABSTRACT

The increasing incidence of myopia has become a global public health concern. Exploring the mechanisms underlying the onset and progression of myopia is crucial for prevention and control. This paper reviews the role of peripheral retinal defocus mechanisms in the development of myopia, with particular emphasis on the interaction between accommodation lag and peripheral retinal defocus, as well as the impact of optical intervention on myopia control effectiveness. In recent years, researchers have developed various optical tools for myopia prevention and control based on the peripheral retinal defocus theory, such as peripheral defocus spectacle lenses, orthokeratology lenses, and peripheral defocus soft contact lenses. This paper aims to provide clinicians with the latest research findings to deepen their understanding of the mechanisms involved in myopia development and to guide the future development and clinical application of myopia prevention and control products.


Subject(s)
Disease Progression , Myopia , Retina , Humans , Myopia/therapy , Myopia/physiopathology , Accommodation, Ocular , Eyeglasses , Contact Lenses, Hydrophilic , Orthokeratologic Procedures/methods , Refraction, Ocular
5.
Transl Vis Sci Technol ; 13(6): 2, 2024 Jun 03.
Article in English | MEDLINE | ID: mdl-38837172

ABSTRACT

Purpose: The purpose of this study was to develop a simplified method to approximate constants minimizing the standard deviation (SD) and the root mean square (RMS) of the prediction error in single-optimized intraocular lens (IOL) power calculation formulas. Methods: The study introduces analytical formulas to determine the optimal constant value for minimizing SD and RMS in single-optimized IOL power calculation formulas. These formulas were tested against various datasets containing biometric measurements from cataractous populations and included 10,330 eyes and 4 different IOL models. The study evaluated the effectiveness of the proposed method by comparing the outcomes with those obtained using traditional reference methods. Results: In optimizing IOL constants, minor differences between reference and estimated A-constants were found, with the maximum deviation at -0.086 (SD, SRK/T, and Vivinex) and -0.003 (RMS, PEARL DGS, and Vivinex). The largest discrepancy for third-generation formulas was -0.027 mm (SD, Haigis, and Vivinex) and 0.002 mm (RMS, Hoffer Q, and PCB00/SN60WF). Maximum RMS differences were -0.021 and +0.021, both involving Hoffer Q. Post-minimization, the largest mean prediction error was 0.726 diopters (D; SD) and 0.043 D (RMS), with the highest SD and RMS after adjustments at 0.529 D and 0.875 D, respectively, indicating effective minimization strategies. Conclusions: The study simplifies the process of minimizing SD and RMS in single-optimized IOL power predictions, offering a valuable tool for clinicians. However, it also underscores the complexity of achieving balanced optimization and suggests the need for further research in this area. Translational Relevance: The study presents a novel, clinically practical approach for optimizing IOL power calculations.


Subject(s)
Lenses, Intraocular , Optics and Photonics , Humans , Optics and Photonics/methods , Biometry/methods , Refraction, Ocular/physiology , Female , Male , Lens Implantation, Intraocular/methods , Aged , Visual Acuity/physiology , Middle Aged
6.
J Refract Surg ; 40(6): e354-e361, 2024 May.
Article in English | MEDLINE | ID: mdl-38848053

ABSTRACT

PURPOSE: To assess the predictive accuracy of new-generation online intraocular lens (IOL) power formulas in eyes with previous myopic laser refractive surgery (LRS) and to evaluate the influence of corneal asphericity on the predictive accuracy. METHODS: The authors retrospectively evaluated 52 patients (78 eyes) with a history of laser in situ keratomileusis (LASIK) or photorefractive keratectomy (PRK) who subsequently underwent cataract surgery. Refractive prediction errors were calculated for 12 no-history new online formulas: 8 formulas with post-LRS versions (Barrett True-K, EVO 2.0, Hoffer QST, and Pearl DGS) using keratometry and posterior/total keratometry measured by IOLMaster 700 and 4 formulas without post-LRS versions (Cooke K6 and Kane) using keratometry and total keratometry. The refractive prediction error, mean absolute error (MAE), and percentages of eyes with prediction errors of ±0.25, ±0.50, ±0.75, ±1.00, and ±1.50 diopters (D) were compared. RESULTS: The MAEs of the 12 formulas were significantly different (F = 83.66, P < .001). The MAEs ranged from 0.62 to 0.94 D and from 1.07 to 1.84 D in the formulas with and without post-LRS versions, respectively. The EVO formula produced the lowest MAE (0.60) and MedAE (0.47), followed by the Barrett True-K (0.69 and 0.50, respectively). Each percentage of eyes with refractive prediction error was also significantly different among the 12 formulas (P < .001). CONCLUSIONS: The EVO and Barrett True-K formulas demonstrate comparable performance to the other existing formulas in eyes with a history of myopic LASIK/PRK. Surgeons should use these formulas with post-LRS versions and input keratometric values whenever possible. [J Refract Surg. 2024;40(6):e354-e361.].


Subject(s)
Keratomileusis, Laser In Situ , Lens Implantation, Intraocular , Lenses, Intraocular , Myopia , Optics and Photonics , Photorefractive Keratectomy , Refraction, Ocular , Visual Acuity , Humans , Retrospective Studies , Myopia/surgery , Myopia/physiopathology , Female , Male , Refraction, Ocular/physiology , Middle Aged , Photorefractive Keratectomy/methods , Keratomileusis, Laser In Situ/methods , Adult , Visual Acuity/physiology , Lasers, Excimer/therapeutic use , Cornea/surgery , Cornea/physiopathology , Reproducibility of Results , Biometry/methods , Phacoemulsification , Aged
7.
J Refract Surg ; 40(6): e371-e380, 2024 May.
Article in English | MEDLINE | ID: mdl-38848054

ABSTRACT

PURPOSE: To report on the prospective evaluation of photorefractive keratectomy (PRK) in experienced ametropic naval aviators that led to the approval of refractive surgery for military pilots. METHODS: This was the first study evaluating refractive surgery in naval aviators. Return to flight status after PRK and clinical outcomes and subjective and objective flight performance were evaluated. RESULTS: A total of 785 U.S. naval aviators were enrolled in the study. Average preoperative refraction was -2.92 ± 1.73 diopters (D) (range: +5.25 to -9.13 D). By 6 months, 85.9% of eyes were within ±0.50 D and 96.4% were within ±1.00 D of emmetropia. 94.4% of eyes achieved 20/20 or better, 74.3% had 20/16 or better, and 45.2% had 20/12.5 or better uncorrected distance visual acuity (UDVA) at 6 months. A total of 78.5% of aviators met return-to-flight criteria by 4 weeks, 83.3% by 8 weeks, and 90.8% by 12 weeks following PRK. All aviators eventually returned to full flight status. Cumulative flight experience included logging more than 48,000 flight hours and 19,500 landings in the 6 months following PRK. Psychometric questionnaire results showed that 78% reported improved ability to detect other aircraft and 92% reported improved ability to land on an aircraft carrier (82% significantly improved) compared to wearing corrective lenses. No one felt their vision was worse in these dynamic environments. All aviators indicated they would undergo the procedure again and would recommend it to a fellow aviator. CONCLUSIONS: This prospective study in U.S. naval aviators determined PRK to be safe and effective in a unique patient population operating in a visually demanding and hazardous environment. The program continues to be enthusiastically supported by aviators and PRK is now allowed in all branches of the military and for National Aeronautics and Space Administration astronauts. [J Refract Surg. 2024;40(6):e371-e380.].


Subject(s)
Lasers, Excimer , Military Personnel , Myopia , Photorefractive Keratectomy , Refraction, Ocular , Visual Acuity , Photorefractive Keratectomy/methods , Humans , Prospective Studies , Visual Acuity/physiology , Adult , Male , United States , Female , Myopia/surgery , Myopia/physiopathology , Lasers, Excimer/therapeutic use , Refraction, Ocular/physiology , Young Adult , Middle Aged , Aerospace Medicine , Treatment Outcome
8.
J Refract Surg ; 40(6): e420-e434, 2024 May.
Article in English | MEDLINE | ID: mdl-38848055

ABSTRACT

PURPOSE: To discuss factors influencing corneal aberrations that might influence the optical quality after intraocular lens (IOL) implantation. METHODS: PubMed and Scopus were the main resources used to search the medical literature. An extensive search was performed to identify relevant articles concerning factors influencing the level of corneal aberrations as of August 27, 2023. The following keywords were used in various combinations: corneal, aberrations, defocus, astigmatism, spherical aberration, coma, trefoil, quadrafoil, intraocular lens, and IOL. RESULTS: Conclusive evidence is lacking regarding the correlation between age and changes in corneal aberrations. Patients with astigmatism have greater corneal higher-order aberrations than those with minimal astigmatism, particularly concerning trefoil and coma. Increased levels of corneal higher-order aberrations are noted following contact lens wear, in patients with dry eye disease, and with pterygium. Increased higher-order aberrations have been reported following corneal refractive surgery and for 3 months following trabeculectomy; regarding intraocular lens surgery, the results remain controversial. CONCLUSIONS: Several factors influence the level of corneal higher-order aberrations. Multifocal and extended depth-of-focus IOLs can share similarities in their optical properties, and the main difference arises in their design and performance with respect to spherical aberration. Preoperative evaluation is critical for proper IOL choice, particularly in corneas with risk of high levels of aberrations. [J Refract Surg. 2024;40(6):e420-e434.].


Subject(s)
Corneal Wavefront Aberration , Lens Implantation, Intraocular , Refraction, Ocular , Visual Acuity , Humans , Corneal Wavefront Aberration/physiopathology , Corneal Wavefront Aberration/etiology , Risk Factors , Visual Acuity/physiology , Refraction, Ocular/physiology , Multifocal Intraocular Lenses , Depth Perception/physiology , Corneal Topography , Cornea/physiopathology
9.
J Refract Surg ; 40(6): e407-e419, 2024 May.
Article in English | MEDLINE | ID: mdl-38848051

ABSTRACT

PURPOSE: To assess clinical outcomes after cataract surgery with bilateral implantation of a new bi-aspheric diffractive intraocular lens (IOL). METHODS: Thirty patients underwent bilateral implantation of the Asqelio Trifocal Toric IOL (AST Products, Inc) and were evaluated 3 months postoperatively. Main outcomes included refractive error, photopic monocular and binocular uncorrected and corrected distance (UDVA, CDVA), intermediate (UIVA, CDIVA) at 60 cm, and near (UNVA, CDNVA) at 40 cm visual acuities. Mesopic monocular and binocular CDNVA were also measured. Defocus curves, binocular contrast sensitivity under photopic and mesopic conditions with and without glare and rotational stability were determined. Patients completed Catquest-9SF and visual symptoms questionnaires. RESULTS: Average values of binocular photopic CDVA, CDIVA, and CDNVA, and mesopic CDNVA were -0.04 ± 0.06, 0.02 ± 0.08, 0.02 ± 0.07, and 0.22 ± 0.11 logMAR, respectively. All patients achieved cumulative CDVA ⩾ 20/25, and CDIVA and CDNVA of 20/32 or better. Binocular depth of focus was approximately 3.25 diopters (D). Mean postoperative spherical equivalent was -0.08 ± 0.26 D, with 95% of eyes within ±0.50 D. Mean postoperative refractive cylinder was -0.22 ± 0.27 D, with 91.67% of eyes within 0.50 D or less, respectively. IOL rotation averaged 0.25 ± 0.65 degrees, all eyes having rotation of less than 5 degrees. Contrast sensitivity was within or above normal levels under photopic and mesopic conditions, with or without glare, except for 12 cpd under mesopic conditions with glare. Questionnaire responses indicated 96.67% of patients were satisfied or very satisfied with postoperative vision, and 80.00% to 96.67% reported no difficulty in different daily activities. CONCLUSIONS: The Asqelio Trifocal Toric IOL demonstrated favorable outcomes, providing excellent visual performance at all distances, precise refractive results, and remarkable rotational stability. Patients reported high satisfaction levels and minimal difficulty in daily activities. [J Refract Surg. 2024;40(6):e407-e419.].


Subject(s)
Contrast Sensitivity , Lens Implantation, Intraocular , Multifocal Intraocular Lenses , Patient Satisfaction , Phacoemulsification , Prosthesis Design , Pseudophakia , Refraction, Ocular , Vision, Binocular , Visual Acuity , Humans , Visual Acuity/physiology , Vision, Binocular/physiology , Male , Female , Aged , Refraction, Ocular/physiology , Pseudophakia/physiopathology , Middle Aged , Contrast Sensitivity/physiology , Surveys and Questionnaires , Prospective Studies , Aged, 80 and over , Lenses, Intraocular , Treatment Outcome
10.
J Refract Surg ; 40(6): e398-e406, 2024 May.
Article in English | MEDLINE | ID: mdl-38848057

ABSTRACT

PURPOSE: To assess the visual and refractive outcomes of patients implanted with a toric extended depth-of-focus (EDOF) intraocular lens (IOL) following cataract surgery. METHODS: A total of 44 eyes implanted with the EDOF LuxSmart toric IOL were evaluated 4 to 6 months postoperatively. The main outcomes measurements evaluated were refractive error, rotational stability, distance, intermediate, and near visual acuities, defocus curve, photopic and mesopic contrast sensitivity, wavefront aberrations, and modulation transfer function, and the Catquest-9SF-questionnaire. RESULTS: The mean postoperative spherical equivalent and cylinder were -0.02 ± 0.26 and -0.17 ± 0.29 diopters (D), respectively. A total of 90.45% and 100% of the eyes had a postoperative spherical equivalent within ±0.50 and ±1.00 D, respectively (this being 93.18% and 100% for the refractive cylinder). The mean rotational stability was 0.61 ± 1.61 degrees. The mean binocular corrected distance visual acuity (CDVA), corrected distance intermediate visual acuity (CDIVA), and corrected distance near visual acuity (CDNVA) were -0.02 ± 0.06, 0.07 ± 0.08, and 0.26 ± 0.09 logMAR, respectively. The CDVA was 20/25 or better in 95.45% of patients, CDIVA was 20/25 or better in 72.73%, and CDNVA was 20/40 or better in 72.73%. The defocus curve showed good visual acuity at distance and intermediate vergences. The contrast sensitivity and optical quality outcomes were good with mean higher order, spherical, and coma aberration values of 0.161 ± 0.155, -0.019 ± 0.048, and 0.080 ± 0.065 µm, respectively. A total of 90.9% of patients were either fairly satisfied or very satisfied with their vision after the surgery, and 77.7% of patients reported no difficulties when reading text in newspapers. CONCLUSIONS: Implantation of the toric pure refractive EDOF technology IOL provides good refractive, optical, and visual quality at different distances, with high levels of patient satisfaction being reported. [J Refract Surg. 2024;40(6):e398-e406.].


Subject(s)
Contrast Sensitivity , Corneal Wavefront Aberration , Depth Perception , Lens Implantation, Intraocular , Lenses, Intraocular , Phacoemulsification , Prosthesis Design , Pseudophakia , Refraction, Ocular , Vision, Binocular , Visual Acuity , Humans , Visual Acuity/physiology , Female , Male , Middle Aged , Aged , Contrast Sensitivity/physiology , Pseudophakia/physiopathology , Refraction, Ocular/physiology , Corneal Wavefront Aberration/physiopathology , Depth Perception/physiology , Vision, Binocular/physiology , Surveys and Questionnaires , Prospective Studies , Patient Satisfaction , Aged, 80 and over , Treatment Outcome
11.
J Refract Surg ; 40(6): e381-e391, 2024 May.
Article in English | MEDLINE | ID: mdl-38848059

ABSTRACT

PURPOSE: To investigate the long-term visual quality and rotational stability after the implantation of Implantable Collamer Lens (ICL) and toric ICL (TICL) (STAAR Surgical) in patients with myopia older than 40 years. METHODS: This study included 82 eyes of 41 patients older than 40 years with myopia who underwent ICL/TICL V4c implantation. The refraction sphere, refraction cylinder, spherical equivalent (SE), uncorrected and corrected distance visual acuity, and anterior segmental parameters were measured preoperatively and at the 1-month, 3-month, and last follow-up visits at 33 to 58 months postoperatively (mean follow-up: 42.56 ± 7.17 months). Wavefront aberrations and TICL rotation were measured using OPD-Scan III (Nidek Co Ltd) at the last follow-up visit. RESULTS: At the last follow-up visit, the overall safety and efficacy index were 1.22 ± 0.26 and 0.88 ± 0.34, respectively, without significant differences between the ICL and TICL groups. Postoperative refraction cylinder was -0.95 ± 0.64 and -0.71 ± 0.54 diopters in the ICL and TICL groups, respectively. The average vault was 467.44 ± 231.98 µm. The average TICL rotation was 5.45 ± 6.61 degrees, positively correlated with the preoperative anterior chamber volume (R2 = 0.1118, P = .026) and clockwise TICL alignment degree (R2 = 0.3110, P = .007) and negatively correlated with the 1-month vault (R2 = 0.1218, P = .008). There were no significant differences in the total, corneal, or internal aberrations and modulation transfer function AreaRatio between the ICL and TICL groups. CONCLUSIONS: Both ICL and TICL presented satisfactory long-term safety, efficacy, and visual quality in patients older than 40 years. Postoperative TICL spontaneous rotation was within the manageable range in the long term. [J Refract Surg. 2024;40(6):e381-e391.].


Subject(s)
Lens Implantation, Intraocular , Myopia, Degenerative , Phakic Intraocular Lenses , Refraction, Ocular , Visual Acuity , Humans , Visual Acuity/physiology , Refraction, Ocular/physiology , Male , Female , Middle Aged , Adult , Follow-Up Studies , Myopia, Degenerative/physiopathology , Myopia, Degenerative/surgery , Retrospective Studies , Corneal Wavefront Aberration/physiopathology , Rotation
12.
J Refract Surg ; 40(6): e392-e397, 2024 May.
Article in English | MEDLINE | ID: mdl-38848056

ABSTRACT

PURPOSE: To compare the effects of corneal allogenic intrastromal ring segment (CAIRS) implantation on topographical measurements and visual outcomes of patients with keratoconus with and without corneal cross-linking (CXL) prior to the time of implantation. METHODS: Sixty-seven eyes with corneal allograft intrastromal ring segment implantation (KeraNatural; Lions VisionGift) due to advanced keratoconus were included in the study. Thirty-seven eyes had no CXL and 30 eyes had had CXL before being referred to the authors. The changes in spherical equivalent (SE), uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), steep keratometry (K1), flat keratometry (K2), mean keratometry (Kmean), maximum keratometry (Kmax), and thinnest pachymetry were retrospectively analyzed 6 months after the implantation. RESULTS: The median age was 29 years in the CXL group and 24.0 years in the non-CXL group (P > .05), respectively. All topographical and visual parameters before implantation were similar in both groups (P > .05 for all parameters). At 6 months, CDVA, K1, and Kmean showed higher improvement in the non-CXL group than the CXL group (P = .030, .018, and .039, respectively). CONCLUSIONS: CAIRS surgery has a flattening effect on both the corneas with and without CXL. The cornea with prior CXL treatment had less flattening effect due to the stiffening effect of prior CXL. [J Refract Surg. 2024;40(6):e392-e397.].


Subject(s)
Collagen , Corneal Stroma , Corneal Topography , Cross-Linking Reagents , Keratoconus , Photosensitizing Agents , Prostheses and Implants , Prosthesis Implantation , Refraction, Ocular , Visual Acuity , Humans , Keratoconus/physiopathology , Keratoconus/metabolism , Keratoconus/drug therapy , Keratoconus/surgery , Corneal Stroma/metabolism , Corneal Stroma/surgery , Cross-Linking Reagents/therapeutic use , Visual Acuity/physiology , Adult , Male , Female , Photosensitizing Agents/therapeutic use , Retrospective Studies , Young Adult , Refraction, Ocular/physiology , Collagen/metabolism , Corneal Pachymetry , Riboflavin/therapeutic use , Photochemotherapy/methods , Adolescent , Ultraviolet Rays , Corneal Transplantation/methods , Middle Aged , Corneal Cross-Linking
13.
J Refract Surg ; 40(6): e362-e370, 2024 May.
Article in English | MEDLINE | ID: mdl-38848058

ABSTRACT

PURPOSE: To identify potential risk factors that increase the likelihood of re-treatment following keratorefractive lenticule extraction (KLEx) for myopia and myopic astigmatism. METHODS: This was a retrospective study of patients with myopia and myopic astigmatism who underwent KLEx using the VisuMax 500 laser (Carl Zeiss Meditec) between April 2015 and December 2020. Patients were assigned to one of two groups: the control group and the re-treatment group (if they had additional refractive surgery within 2 years of the primary treatment). The effect of different preoperative, intraoperative, and postoperative parameters on the re-treatment rate was analyzed. RESULTS: Overall 1,822 eyes of 938 patients were analyzed. In total, 2.96% of eyes (n = 54) underwent re-treatment. The re-treated patients were more likely to be women and have high myopia, high astigmatism, steep corneas, higher ocular residual astigmatism, and residual myopic and/or astigmatic refractive error. In contrast, no significant correlation was found between re-treatment rate and age, chord µ, type of astigmatism, and corneal thickness. CONCLUSIONS: Factors associated with higher rates of retreatment after KLEx included female gender, manifest refractive high myopia (> -5.00 diopters [D]), astigmatism (> 2.00 D), spherical equivalent (> 6.00 D), ocular residual astigmatism, steeper corneas, and postoperative residual myopic and astigmatic refractive errors. This study may help to preoperatively detect patients at risk for re-treatment, improve preoperative patient counseling, and optimize patient selection to reduce future re-treatment rates. [J Refract Surg. 2024;40(6):e362-e370.].


Subject(s)
Astigmatism , Lasers, Excimer , Myopia , Refraction, Ocular , Reoperation , Visual Acuity , Humans , Retrospective Studies , Male , Astigmatism/surgery , Astigmatism/physiopathology , Female , Adult , Risk Factors , Myopia/surgery , Myopia/physiopathology , Visual Acuity/physiology , Refraction, Ocular/physiology , Lasers, Excimer/therapeutic use , Young Adult , Corneal Stroma/surgery , Corneal Topography , Middle Aged , Adolescent , Corneal Surgery, Laser/methods
14.
BMC Ophthalmol ; 24(1): 207, 2024 May 06.
Article in English | MEDLINE | ID: mdl-38711043

ABSTRACT

PURPOSE: To understand the ocular biometric parameters characteristics and refractive errors in 3-to 6-year-old preschool children in Chengdu, China, and to investigate the prevalence of refractive errors. METHOD: A school-based cross-sectional study was conducted in Chengdu from 2020 to2022 with a total of 666 kindergartens. All children were measured by non-cycloplegic autorefraction and uncorrected visual acuity (UCVA) and ocular biometric parameters. Finally, univariate linear regression models were used to analyze the relationship between ocular biometric parameters and refraction. RESULTS: A total of 108,578 preschool children aged 3-6 underwent examinations, revealing a myopia prevalence of 6.1%. The mean axial length (AL), keratometry (K), corneal radius (CR), axial length/corneal radius (AL/CR) Ratio, central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), and vitreous chamber depth (VCD) were 22.35 ± 0.69 mm, 43.35 ± 1.58 D, 7.80 ± 0.28 mm, 2.87 ± 0.08, 533.31 ± 32.51 µm, 2.70 ± 0.28 mm, 3.91 ± 0.27 mm, and 15.20 ± 0.68 mm, respectively. With increasing age, AL, CR, AL/CR ratio, CCT, ACD, LT, and VCD also increased. Regardless of age, males consistently exhibited longer AL, flatter corneal curvature, shallower ACD, thicker CCT, thinner LT, and longer VCD compared to females. AL, K, CR, LT, and VCD all showed significant linear relationships with SE (all P < 0.001) in univariate linear regression analysis after adjusting for gender and age. CONCLUSION: The prevalence of myopia among preschool children aged 3-6 in Chengdu is relatively low. Ocular biometric parameters affecting refractive errors include AL, K, CR, LT, and VCD. The preschool period serves as a critical phase for myopia prevention and control.


Subject(s)
Biometry , Refraction, Ocular , Visual Acuity , Humans , Female , Male , Cross-Sectional Studies , China/epidemiology , Refraction, Ocular/physiology , Child, Preschool , Child , Visual Acuity/physiology , Prevalence , Axial Length, Eye , Cornea/pathology , Cornea/anatomy & histology , Refractive Errors/epidemiology , Refractive Errors/physiopathology , Anterior Chamber/diagnostic imaging , Anterior Chamber/pathology , Myopia/epidemiology , Myopia/physiopathology
15.
J Refract Surg ; 40(5): e313-e320, 2024 May.
Article in English | MEDLINE | ID: mdl-38717079

ABSTRACT

PURPOSE: To assess the clinical outcomes and safety profiles of patients who underwent immediate sequential bilateral phakic lens surgery. METHODS: This retrospective multicenter study included 254 consecutive patients (508 eyes) who underwent bilateral same-day Implantable Collamer Lens (ICL) (STAAR Surgical) surgery. The authors focused on 1-year postoperative clinical outcomes and adverse events. RESULTS: In the initial cohort, 176 patients (352 eyes) met inclusion criteria. Of these, 335 eyes underwent myopic ICL placement, and 17 eyes received a hyperopic ICL. Notably, 87% of eyes achieved ±0.50 diopters (D) and 95% achieved ±1.00 D of the intended refraction. One year postoperatively, 78% of eyes demonstrated optimal vaulting (250 to 750 µm), with a significant 19% reduction in vaulting observed over the 12 months (P < .001). Only minor adverse events, including early cataract formation (1 case), secondary toric ICL rotation (3 cases), and ICL exchange due to inappropriate vaulting (6 cases), were noted. CONCLUSIONS: The findings corroborate the safety and efficacy of immediate sequential bilateral phakic lens surgery and indicate its potential as a treatment option. The low incidence of minor adverse events further reinforces its favorable safety profile. [J Refract Surg. 2024;40(5):e313-e320.].


Subject(s)
Hyperopia , Lens Implantation, Intraocular , Myopia , Phakic Intraocular Lenses , Refraction, Ocular , Visual Acuity , Humans , Retrospective Studies , Male , Visual Acuity/physiology , Female , Adult , Myopia/surgery , Myopia/physiopathology , Refraction, Ocular/physiology , Hyperopia/surgery , Hyperopia/physiopathology , Young Adult , Treatment Outcome , Middle Aged , Postoperative Complications , Follow-Up Studies , Adolescent
16.
J Refract Surg ; 40(5): e328-e335, 2024 May.
Article in English | MEDLINE | ID: mdl-38717080

ABSTRACT

PURPOSE: To evaluate moderate to high astigmatism corrections on the outcomes of SmartSight lenticule extraction for myopic astigmatism with a new femtosecond laser system. METHODS: Two hundred ninety-two eyes consecutively treated for myopic astigmatism with astigmatism magnitude greater than 1.00 diopter (D) were evaluated at the 6-month follow-up visit. The mean age of the patients was 29 ± 6 years with a mean spherical equivalent of -5.06 ± 2.20 diopters (D) and a mean magnitude of refractive astigmatism of 1.74 ± 0.61 D. RESULTS: At 6 months, astigmatism was 0.10 ± 0.20 D. Uncorrected and corrected distance visual acuities (UDVA and CDVA, respectively) were both 0.0 ± 0.1 logMAR. Differences between postoperative UDVA and preoperative CDVA and the change in CDVA were both +0.4 ± 0.7 lines better than preoperatively (P < .0003). CONCLUSIONS: Lenticule extraction treatment using Smart-Sight is safe and efficacious at 6 months. Findings suggest that moderate to high astigmatism improves after SmartSight lenticule extraction in the treatment of myopic astigmatism. [J Refract Surg. 2024;40(5):e328-e335.].


Subject(s)
Astigmatism , Corneal Stroma , Lasers, Excimer , Myopia , Refraction, Ocular , Visual Acuity , Humans , Astigmatism/physiopathology , Astigmatism/surgery , Visual Acuity/physiology , Retrospective Studies , Adult , Refraction, Ocular/physiology , Male , Female , Myopia/surgery , Myopia/physiopathology , Young Adult , Corneal Stroma/surgery , Lasers, Excimer/therapeutic use , Corneal Topography , Follow-Up Studies , Treatment Outcome , Corneal Surgery, Laser/methods
17.
J Refract Surg ; 40(5): e336-e343, 2024 May.
Article in English | MEDLINE | ID: mdl-38717081

ABSTRACT

PURPOSE: To assess and compare the visual acuity and refractive outcomes of topography-guided laser in situ keratomileusis (LASIK) based on the fitting-shape-based refractive compensated and Phorcides software strategies. METHODS: Consecutive patients who underwent topography-guided LASIK were included in this study. Through double-masked simple randomization, patients were assigned to the Zhang & Zheng Auto-compensate Refraction (ZZ AR) group (the fitting-shape-based refractive compensated strategy using the ZZ AR calculator was used) or the Phorcides group (the topography analysis algorithm in Phorcides software [Phorcides LLC] was used). Only one eye per patient with binocular correction was randomly enrolled. The preoperative and postoperative visual acuities and refraction were analyzed at the 6-month follow-up visit. RESULTS: The ZZ AR and Phorcides groups comprised 156 and 147 eyes, respectively. At the 6-month postoperative follow-up visit, the median (range) absolute residual cylindrical refraction was 0.35 (1.01) and 0.47 (1.63) diopters (D) for the ZZ AR and Phorcides groups, respectively (P < .001). The percentages of patients with residual cylindrical power within 0.25 D were 29.49% and 13.61% for the ZZ AR and Phorcides groups, respectively (P = .001). Based on the percentages of patients with residual cylindrical powers within 0.50 and 1.00 D, the ZZ AR group showed better outcomes (P = .02 and .01). The percentage of patients with visual acuity better than 20/16 was significantly higher for the ZZ AR group than for the Phorcides group (P = .03). CONCLUSIONS: The fitting-shape-based refractive compensated strategy for topography-guided LASIK procedures can better optimize the visual acuity and astigmatic refraction than the Phorcides software strategy. [J Refract Surg. 2024;40(5):e336-e343.].


Subject(s)
Corneal Topography , Keratomileusis, Laser In Situ , Lasers, Excimer , Myopia , Refraction, Ocular , Surgery, Computer-Assisted , Visual Acuity , Humans , Keratomileusis, Laser In Situ/methods , Visual Acuity/physiology , Prospective Studies , Refraction, Ocular/physiology , Adult , Male , Female , Lasers, Excimer/therapeutic use , Double-Blind Method , Myopia/surgery , Myopia/physiopathology , Young Adult , Surgery, Computer-Assisted/methods , Middle Aged , Cornea/surgery , Cornea/physiopathology , Follow-Up Studies
18.
J Refract Surg ; 40(5): e291-e303, 2024 May.
Article in English | MEDLINE | ID: mdl-38717083

ABSTRACT

PURPOSE: To compare differences in corneal densitometry (CD) and higher order aberrations (HOAs) in eyes that underwent small incision lenticule extraction (SMILE) and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) for the treatment of myopia and myopic astigmatism at postoperative months 3, 6, and 12, and to evaluate their changes in a separate cohort of eyes after SMILE enhancement. METHODS: In this prospective, randomized, paired-eye clinical trial, consecutive eligible participants were randomized to undergo SMILE or FS-LASIK in either eye. Main outcome measures were CD and HOAs preoperatively and at 3, 6, and 12 months postoperatively. A separate cohort of consecutive patients who had SMILE and underwent enhancement were also included for comparison. RESULTS: For CD, no significant differences were found between SMILE and FS-LASIK up to month 12. For HOA measured by wavefront aberrometry, both SMILE and FS-LASIK had an increase in total root mean square (RMS) HOAs, spherical aberration (SA), and vertical coma up to month 12. SMILE had an additional increase in vertical quatrefoil, and FS-LASIK had an increase in horizontal coma at month 12. FS-LASIK had higher SA than SMILE, whereas SMILE had higher vertical quatrefoil than FS-LASIK at month 12. Central and posterior zone CD had significantly decreased after SMILE enhancement compared to after primary SMILE up to 2 years after enhancement. RMS HOAs, lower order aberrations, and SA were all increased after SMILE enhancement compared to after primary SMILE. CONCLUSIONS: SMILE induced lower SA but higher vertical quatrefoil than FS-LASIK at 1 year. Both SMILE and FS-LASIK had similar increases in RMS HOAs and vertical coma up to 1 year. There were no differences in CD between both groups. SMILE enhancement additionally had decreased central and posterior CD but greater RMS HOAs and SA compared to primary SMILE. [J Refract Surg. 2024;40(5):e291-e303.].


Subject(s)
Aberrometry , Astigmatism , Cornea , Corneal Stroma , Corneal Wavefront Aberration , Densitometry , Keratomileusis, Laser In Situ , Lasers, Excimer , Myopia , Refraction, Ocular , Visual Acuity , Humans , Keratomileusis, Laser In Situ/methods , Corneal Wavefront Aberration/physiopathology , Prospective Studies , Myopia/surgery , Myopia/physiopathology , Adult , Female , Male , Lasers, Excimer/therapeutic use , Visual Acuity/physiology , Corneal Stroma/surgery , Cornea/surgery , Cornea/physiopathology , Young Adult , Refraction, Ocular/physiology , Astigmatism/surgery , Astigmatism/physiopathology , Corneal Surgery, Laser/methods , Corneal Topography
19.
J Refract Surg ; 40(5): e321-e327, 2024 May.
Article in English | MEDLINE | ID: mdl-38717082

ABSTRACT

PURPOSE: To evaluate the characteristic of corrective epithelial thickness after femtosecond laser-assisted lenticule intrastromal keratoplasty (LIKE) to correct moderate-to-high hyperopia. METHODS: The prospective case series study of the LIKE procedure was performed to correct moderate-to-high hyperopia. The epithelial thickness map was generated by anterior segment optical coherence tomography (AS-OCT) in the corneal central 9-mm zone. Keratometry and corneal higher order aberrations were analyzed by Pentacam (Oculus Optikgeräte GmbH) preoperatively and postoperatively. RESULTS: In the 26 eyes of 13 participants who underwent the LIKE procedure for moderate-to-high hyperopia, the attempted spherical equivalence (SEQ) was +6.50 ± 1.09 diopters (D). Compared to the preoperative epithelial thickness maps, the postoperative epithelial thickness had become significantly thinner in the central 5-mm zone; the difference was 6 to 7 µm. The paracentral epithelium performed nonuniform remodeling; the thinnest epithelial thickness was located in the inferotemporal section, which has the greatest difference from the superonasal; the difference between these two was approximately 3 µm. Through correlation analysis, it was found that the sections with thinner epithelium were significantly related to corneal curvature and corneal vertical coma. CONCLUSIONS: The LIKE procedure can be used to correct moderate-to-high hyperopia. This study further indicated the epithelial remodeling characteristic after the LIKE procedure: the central and paracentral corneal epithelial thickness becomes thinner, and the epithelial thickness distributes non-uniformly, which may be the important factor of the postoperative curvature asymmetric distribution and induction of corneal vertical coma. [J Refract Surg. 2024;40(5):e321-e327.].


Subject(s)
Corneal Stroma , Corneal Topography , Epithelium, Corneal , Hyperopia , Refraction, Ocular , Tomography, Optical Coherence , Visual Acuity , Humans , Hyperopia/surgery , Hyperopia/physiopathology , Prospective Studies , Corneal Stroma/surgery , Corneal Stroma/pathology , Male , Female , Adult , Visual Acuity/physiology , Epithelium, Corneal/surgery , Epithelium, Corneal/pathology , Refraction, Ocular/physiology , Middle Aged , Lasers, Excimer/therapeutic use , Young Adult , Corneal Wavefront Aberration/physiopathology , Corneal Surgery, Laser/methods , Eye Diseases, Hereditary
20.
J Refract Surg ; 40(5): e344-e352, 2024 May.
Article in English | MEDLINE | ID: mdl-38717086

ABSTRACT

PURPOSE: To compare the effects of three common refractive surgeries on corneal biomechanics. METHODS: Two hundred seven patients who had refractive surgery were included in this study, of whom 65 received transepithelial photorefractive keratectomy (tPRK), 73 received femtosecond laser-assisted laser in situ keratomileusis (FSLASIK), and 69 received small incision lenticule extraction (SMILE). Each patient had biomechanical measurements using the Corvis ST (Oculus Optikgeräte GmbH) preoperatively and at 3 and 6 months postoperatively. The measurements included five parameters expected to be associated with corneal biomechanics: deformation amplitude ratio at 2 mm (DAR2), integrated inverse radius (IIR), stiffness parameter at first applanation (SP-A1), highest concavity time (HCT), and the updated stress-strain index (SSIv2). The variations in these parameters postoperatively among the three surgeries, and their relationship with corneal thickness (CCT) and intraocular pressure measured by the Dynamic Contour Tonometer (DCT-IOP) were analyzed. RESULTS: SP-A1 decreased significantly from preoperatively to 3 months postoperatively in all three groups, whereas DAR2 and IIR increased significantly, all indicating stiffness losses. Between 3 and 6 months postoperatively, the results were inconsistent, with DAR2 decreasing (indicating stiffness increases) and IIR increasing (denoting stiffness decreases) in the FS-LASIK and SMILE groups. The decrease in SSIv2 (the only measure of corneal material stiffness) postoperatively was comparatively less pronounced at both 3 and 6 months postoperatively. On the other hand, HCT remained generally stable after all three surgeries. Unlike DAR2, IIR, and SP-A1, the changes postoperatively in stiffness parameters HCT and SSIv2 were independent of the corresponding changes in both DCT-IOP and CCT. CONCLUSIONS: Among the stiffness parameters considered, SSIv2 was not correlated with CCT or DCT-IOP, and holds promise for representing the corneal material stiffness and how it remains largely unaffected by refractive surgeries. Overall, FS-LASIK had the most significant impact on corneal stiffness, followed by SMILE, and finally tPRK. [J Refract Surg. 2024;40(5):e344-e352.].


Subject(s)
Cornea , Elasticity , Intraocular Pressure , Keratomileusis, Laser In Situ , Lasers, Excimer , Myopia , Humans , Cornea/physiopathology , Cornea/surgery , Adult , Female , Male , Biomechanical Phenomena , Lasers, Excimer/therapeutic use , Keratomileusis, Laser In Situ/methods , Young Adult , Elasticity/physiology , Myopia/surgery , Myopia/physiopathology , Intraocular Pressure/physiology , Photorefractive Keratectomy/methods , Visual Acuity/physiology , Refraction, Ocular/physiology , Middle Aged , Prospective Studies , Corneal Surgery, Laser/methods , Corneal Topography
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