Adenoid cystic carcinoma of the parotid gland associated with salivary calculi: An unusual presentation.

Adenoid cystic carcinomas (ACC) of the head and neck are relatively rare tumors, consisting of approximately 10-15% of all salivary gland neoplasms. ACC, a slow-growing aggressive malignant tumor of salivary gland commonly seen in the submandibular, sublingual, minor salivary glands is seldom found in the parotid. Calculus, the common cause of salivary gland dysfunction is usually identified in submandibular salivary gland because of its duct anatomy and physiochemical characteristic serous secretion. We report an unusual case of co-existent presentation of ACC with salivary calculi in the parotid gland which is never been reported in the literature. Co-existence of ductal calculi and ACC is rare. Presence of parotid calculus could be due to long standing ductal obstruction by the slow-growing ACC of the parotid or other possibility is that the malignancy could have developed because of chronic irritation by parotid calculi. Confirmatory studies are required to understand its mutual pathological association.

Exames complementares por imagens no diagnóstico e no planejamento cirúrgico de patologias em glândulas salivares / Salivary glands diseases imaging to make diagnoses and surgical decisions

Mudanças no tamanho de uma glândula salivar podem indicar doenças sistêmicas. Porém, é difícil avaliar corretamente estas mudanças somente através de exame clínico. Métodos complementares podem auxiliar de forma fundamental no diagnóstico. Por causa da importância de se identificar pequenos cálculos nas glândulas salivares como a causa de um conjunto de sintomas, radiografias intrabucais etomografia computadorizada são os melhores exames para uma avaliação inicial. A sialografia pode ser utilizada na avaliação de sialoadenites crônicas. Os autores discutem estes e outros exames,como a cintilografia e a ultra-sonografia, no diagnóstico e no tratamento das patologias das glândulas salivares

Multiple intraparenchymal parotid calculi: a case report and review of the literature.

We describe an unusual case of bilateral intraparenchymal parotid stones with unilateral parotitis in a 17-year-old boy. The patient went on to develop multiple parotid abscesses, which we treated with a superficial parotidectomy. To our knowledge, this is only the second report of intraparenchymal parotid stones in a pediatric patient.

Sialolithiasis: mechanism of calculi formation and etiologic factors.

BACKGROUND: Sialolithiasis is a common disease of salivary glands. The etiology of these calculi is little known and their exact mechanism of formation is unknown. METHODS: The composition and structure of 21 sialoliths were studied and the composition of the saliva of each corresponding patient was determined (pH, calcium, magnesium, phosphorus, citrate and phytate). RESULTS: Eighteen sialoliths exhibited similar macro and microstructure, being constituted by hydroxyapatite (HAP) and organic matter, normally arranged in a multilayer structure. The three remaining sialoliths were exclusively constituted by organic matter. The salivary Ca of patients with HAP calculi was significantly higher than that found in the saliva of the healthy group. The salivary phytate concentration of patients with HAP calculi was significantly inferior to that found in patients with calculi exclusively formed by organic matter, as well as to that found in saliva of healthy group. Significant differences between the salivary magnesium concentrations of patients with HAP calculi and the control group were also observed. No significant differences between pH and citrate concentrations of the three groups were found. CONCLUSIONS: It was concluded that the deficit of crystallization inhibitors such as myo-inositol hexaphosphate (phytate) was also an important etiologic factor implied in the sialolith development.