ABSTRACT
Not available.
Subject(s)
Sarcoidosis/history , Warfare , England , France , Genetic Predisposition to Disease , History, 15th Century , History, Medieval , Humans , Phenotype , Sarcoidosis/diagnosis , Sarcoidosis/geneticsABSTRACT
The 1930 International Labour Office Conference on silicosis in Johannesburg identified silicosis by setting a medicolegal framework to its nosology: as with other occupational illnesses, its medical content was fixed under economic pressure. This article follows a reading of all the proceedings of this conference (debates and reports of experts) to examine their potential impact on the etiology and nosology of other diseases, specifically sarcoidosis and pulmonary alveolar proteinosis (PAP), "idiopathic" diseases in which inorganic particles may be involved. We propose renewed study of the role of inorganic particles in these diseases. To do this, we propose to mobilize detection means such as mineralogical analysis and electron microscopy and in depth interviewing that are currently seldom used in France, in order to establish diagnosis and the potential occupational and environmental origin of these diseases.
Subject(s)
Congresses as Topic/history , Pulmonary Alveolar Proteinosis/history , Sarcoidosis/history , Silicosis/history , History, 20th Century , Humans , Pneumoconiosis/classification , Pneumoconiosis/diagnosis , Pneumoconiosis/history , Pulmonary Alveolar Proteinosis/classification , Pulmonary Alveolar Proteinosis/diagnosis , Sarcoidosis/classification , Sarcoidosis/diagnosis , Silicosis/classification , Silicosis/diagnosis , South AfricaABSTRACT
Sarcoidosis is a chronic systemic disease of unknown origin and uncertain prognosis that most commonly affects young adults, and frequently presents with bilateral hilar lymphadenopathy, pulmonary infiltrates and ocular and skin lesions. The diagnosis is established when characteristic clinical-radiological features are supported by compatible histopathology of epithelioid cell granulomas, following exclusion of known causes of granulomatous inflammation. Indeed, sarcoidosis belongs to a large family of disorders that share granuloma formation as common denominator. Since its first description by Jonathan Hutchinson in 1869, sarcoidosis has generated enormous interest and considerable controversy. In Hutchinson's day, it was considered a dermatological condition, which gradually evolved into a multisystem disorder associated in the majority of cases with respiratory abnormalities. With time, it has also become clear that sarcoidosis occurs throughout the world, affecting individuals of both genders and all races, although its prevalence varies widely across ethnic and racial groups. In recent years, advances in different disciplines, particularly biochemistry, genetics, immunology and molecular biology, have improved dramatically our understanding of the disease. Yet, the critical questions regarding who gets sarcoidosis and whether it has an infectious origin remain unanswered. Sarcoidosis has a distinguished medical history that covers the last 150 years. Right from the time of seminal contributions by Hutchinson, Besnier and Boeck medical discussion on sarcoidosis has always been animated and to a certain extent emotional. Such discussions will inevitable continue until the true cause of the disease has been found, hopefully in the near future.
Subject(s)
Granuloma/diagnosis , Lymphatic Diseases/diagnosis , Pneumonia/diagnosis , Sarcoidosis/diagnosis , Adult , Eye/pathology , Female , Granuloma/diagnostic imaging , Granuloma/history , Granuloma/pathology , History, 19th Century , History, 20th Century , History, 21st Century , Humans , Lymphatic Diseases/diagnostic imaging , Lymphatic Diseases/history , Lymphatic Diseases/pathology , Male , Middle Aged , Pneumonia/diagnostic imaging , Pneumonia/history , Pneumonia/pathology , Radiography , Sarcoidosis/diagnostic imaging , Sarcoidosis/history , Sarcoidosis/pathology , Skin/diagnostic imaging , Skin/pathologySubject(s)
Sarcoidosis , Child , History, 20th Century , Humans , Idaho , Sarcoidosis/classification , Sarcoidosis/diagnosis , Sarcoidosis/history , UtahSubject(s)
Famous Persons , Politics , Sarcoidosis/diagnosis , Diagnosis, Differential , France , History, 18th Century , Humans , Retrospective Studies , Sarcoidosis/historySubject(s)
Famous Persons , Sarcoidosis/history , France , French Revolution , History, 18th Century , HumansABSTRACT
Se presenta el caso de una mujer de 30 años, que presentaba síntomas respiratorios y constitucionales de dos meses de evolución. Se documentó exudado linfocitario y proteinuria, y se descartó tuberculosis y neoplasia maligna. Se le practicó biopsia pleuraly de ganglio linfático, que reportaron sarcoidosis. Se tomó biopsia renal por presencia de proteinuria con pruebas serológicas negativas, y se encontró glomerulonefritis membranosa secundaria. Se inició tratamiento con prednisolona...
We describe the case of a 30 years old female with a two month history of respiratory symptoms and malaise. A lymphocytic pleural effusion and proteinuria were documented,tuberculosis and malignancy were ruled out. Biopsy of lymph nodes and pleura confirmed sarcoidosis. Due to non-nephrotic proteinuria with negative serology tests, kidney biopsy was performed, showing secondary membranous glomerulonephritis. Treatment with prednisolone was started...
Subject(s)
Glomerulonephritis , Kidney/injuries , Sarcoidosis/history , Sarcoidosis/prevention & controlSubject(s)
Lung Diseases/history , Sarcoidosis/history , Germany , History, 19th Century , Humans , MaleABSTRACT
In the years preceding and following the turn of the 19th century several publications appeared independently that drew attention to what is now regarded as sarcoidosis. The first recorded and illustrated example is attributed to Jonathan Hutchinson of London. It appeared in Illustrations of Clinical Surgery (1877).
Subject(s)
Internal Medicine/history , Sarcoidosis/history , History, 19th Century , History, 20th Century , Humans , United StatesSubject(s)
Dermatology/history , Sarcoidosis/history , Animals , Disease Models, Animal , History, 19th Century , History, 20th Century , HumansABSTRACT
Sarcoidosis is a multisystem granulomatous disorder of unknown etiology first named and described in the 19th century. The diagnosis usually requires the finding of noncaseating epithelioid cell granulomas in more than one organ and exclusion of other disorders known to cause granulomatous disease. The incidence of nervous system involvement in sarcoidosis is about 5%. Sarcoidosis may involve any part of the nervous system. Corticosteroids remain the mainstay of treatment of neurosarcoidosis.
Subject(s)
Nervous System Diseases/history , Sarcoidosis/history , Adrenal Cortex Hormones/history , Adrenal Cortex Hormones/therapeutic use , History, 19th Century , Humans , Nervous System Diseases/diagnosis , Nervous System Diseases/therapy , Sarcoidosis/diagnosis , Sarcoidosis/therapyABSTRACT
The definition of sarcoidosis in the past international conference on sarcoidosis is introduced. Furthermore, the diagnostic criteria proposed by Japanese Research Committee for Diffuse Lung Diseases of the Japan Ministry of Welfare was discussed upon the problem.
Subject(s)
Sarcoidosis , History, 19th Century , History, 20th Century , Humans , Sarcoidosis/diagnosis , Sarcoidosis/history , Terminology as TopicABSTRACT
Jonathan Hutchinson is a convenient starting point for a glimpse through the history and milestones of sarcoidosis. The influence of various countries is recognized by its pioneers of sarcoidosis. This historical account is brought up-to-date by the word "NOW," implying how are we addressing the enigma that continues to elude us--namely, the cause of sarcoidosis. This review of the past 150 years or so outlines the countries and personalities that have carried the Olympic torch.