Trichinella: what is going on during nurse cell formation?

Recent molecular studies have revealed that many genes are mobilized during nurse cell formation, including those involved in activation and proliferation of satellite cells, dedifferentiation, cell cycle re-entry and arrest, apoptosis and transformation. This article reviews the kinetics of gene expression from a cellular biology point-of-view in an effort to dissect the complex events that lead to unusual pathological changes after a Trichinella infection.