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1.
Adv Skin Wound Care ; 33(9): 497-500, 2020 Sep.
Article in English | MEDLINE | ID: mdl-32694300

ABSTRACT

BACKGROUND: Fasciotomy incision closure is often performed with skin grafts that can lead to cosmetic and functional complications after surgical intervention. Because fasciotomy incisions do not result in skin loss, the authors hypothesized that better closure can be achieved by reducing tissue edema with negative-pressure wound therapy (NPWT) and reducing stress on the skin with the shoelace surgical technique. METHODS: This 1-year prospective study included eight patients with acute compartment syndrome after extremity fractures and/or blunt injuries. Patients were treated with fasciotomies closed with the shoelace technique and NPWT for wound margin approximation. The NPWT device was changed every second day; the shoelace traction tension was tightened at the same time. MAIN RESULTS: The mean time from fasciotomy to wound closure was 11.8 days (range, 5-30 days). There was no need for a skin graft or flap in any patient. CONCLUSIONS: The shoelace technique plus NPWT may be successful in closing skin fasciotomies after acute compartment syndrome without causing additional morbidity.


Subject(s)
Compartment Syndromes/surgery , Negative-Pressure Wound Therapy/methods , Silicone Elastomers/therapeutic use , Wound Healing/physiology , Adult , Fasciotomy/methods , Female , Humans , Male , Middle Aged , Prospective Studies , Treatment Outcome
2.
Acta Cir Bras ; 35(4): e202000407, 2020.
Article in English | MEDLINE | ID: mdl-32555938

ABSTRACT

PURPOSE: To evaluate whether silicone foam implants have a different evolution pattern compared to conventional texture implants. METHODS: Fifty-eight female patients underwent surgery. They were divided into two groups (silicone foam - Lifesil® - and microtexturized silicone - Lifesil®). The evolution was analyzed in postoperative consultations, with physical examination, photographic documentation and filling in a satisfaction questionnaire, in the postoperative period of one month, four months, one year and then annually, up to a maximum of 3 years of follow-up. RESULTS: There were no statistically significant differences in presence of rippling, stretch marks, breast ptosis, capsular contracture and quality of scars. There was a higher rate of patients who were very satisfied with the outcome 360 days after surgery in the group receiving silicone foam implants (p = 0.036). CONCLUSION: In short time, silicone foam envelope implants proved to be as reliable as textured silicone envelope implants, making them an option for augmentation mammoplasty.


Subject(s)
Breast Implantation/methods , Breast Implants , Silicone Elastomers/therapeutic use , Adult , Breast/drug effects , Breast Implantation/adverse effects , Breast Implants/adverse effects , Female , Foreign-Body Reaction/pathology , Humans , Male , Middle Aged , Patient Satisfaction , Postoperative Complications , Prospective Studies , Reproducibility of Results , Risk Factors , Time Factors , Treatment Outcome , Young Adult
3.
Int J Artif Organs ; 43(5): 343-347, 2020 May.
Article in English | MEDLINE | ID: mdl-31739725

ABSTRACT

PURPOSE: Patients with maxillofacial deformities always seek for aesthetic prosthesis. Recently, three-dimensional printing technologies have been used for dental treatments on such patients. CASE REPORT: A 24-year-old man reported to the Department of Prosthodontics for replacement of his missing right ear induced by a trauma. A magnet-retained auricular prosthesis was planned for the patient. Three-dimensional scanning was performed on the healthy side by using a three-dimensional optical scanner and the data were mirrored. The mirrored image was then imported to a software and a virtual model of the future prosthesis was obtained for the defect side. A three-dimensional printer was used to fabricate a negative mold for the mirrored image by using additive manufacturing. Initially, an impression of the defect side was made; then, the cast model was obtained in a dental flask. Magnets of the prosthesis were inserted to the acrylic resin framework on the cast model. Room temperature vulcanized silicone elastomer was mixed and poured into the three-dimensionally fabricated mold. Then, the flask was placed over the negative mold firmly. After polymerization of the silicone, the auricular prosthesis was delivered to the patient and the patient was instructed to clean the prosthesis daily. CONCLUSIONS: Three-dimensional printing technology was used for the fabrication of the patient's missing ear. This method eliminated the conventional laboratory steps and reduced the number of stages of the fabrication of a silicone prosthesis. The negative mold of the defect side allowed us a direct fabrication of the silicone prosthesis without a need for waxing or flasking procedures.


Subject(s)
Amputation, Traumatic/surgery , Ear, External/injuries , Maxillofacial Prosthesis , Printing, Three-Dimensional , Prosthesis Implantation/methods , Acrylic Resins/therapeutic use , Biocompatible Materials/therapeutic use , Computer-Aided Design , Humans , Male , Prosthesis Design , Silicone Elastomers/therapeutic use , Treatment Outcome , Young Adult
4.
Acta cir. bras ; 35(4): e202000407, 2020. tab, graf
Article in English | LILACS | ID: biblio-1130635

ABSTRACT

Abstract Purpose To evaluate whether silicone foam implants have a different evolution pattern compared to conventional texture implants. Methods Fifty-eight female patients underwent surgery. They were divided into two groups (silicone foam - Lifesil® - and microtexturized silicone - Lifesil®). The evolution was analyzed in postoperative consultations, with physical examination, photographic documentation and filling in a satisfaction questionnaire, in the postoperative period of one month, four months, one year and then annually, up to a maximum of 3 years of follow-up. Results There were no statistically significant differences in presence of rippling, stretch marks, breast ptosis, capsular contracture and quality of scars. There was a higher rate of patients who were very satisfied with the outcome 360 days after surgery in the group receiving silicone foam implants (p = 0.036). Conclusion In short time, silicone foam envelope implants proved to be as reliable as textured silicone envelope implants, making them an option for augmentation mammoplasty.


Subject(s)
Humans , Male , Female , Adult , Young Adult , Silicone Elastomers/therapeutic use , Breast Implantation/methods , Postoperative Complications , Time Factors , Breast/drug effects , Prospective Studies , Reproducibility of Results , Risk Factors , Foreign-Body Reaction/pathology , Treatment Outcome , Patient Satisfaction , Breast Implants/adverse effects , Breast Implantation/adverse effects , Middle Aged
5.
J Vis Exp ; (143)2019 01 07.
Article in English | MEDLINE | ID: mdl-30663660

ABSTRACT

Angiography is an essential tool for the study of vascular structures in various research fields. The aim of this study is to introduce a simple angiographic method for examining the fine vascular structure of unfixed, fresh tissue using a silicone rubber injection compound and soft tissue X-ray system. This study is especially focused on flap territories used in reconstructive surgery. This study employs angiography with a silicone rubber injection compound in various experimental conditions using Sprague-Dawley rats. First, 15 mL of MV compound and 15 mL of diluent is mixed. Then, 1.5 mL of the curing agent is prepared, and a 24G catheter is cannulated in the common carotid artery of the rat. A three-way stopcock is then connected to a catheter, and the radiopaque agent, after being mixed with the prepared curing agent, is injected immediately without spillage. Finally, as the agent solidifies, the specimen is harvested, and an angiographic image is obtained using a soft tissue X-ray system. This method indicates that high-quality angiography showing fine vascular structures can be easily and simply obtained within in a short period of time.


Subject(s)
Angiography/methods , Silicone Elastomers/therapeutic use , X-Rays , Animals , Humans , Injections , Male , Rats , Rats, Sprague-Dawley , Rubber , Silicone Elastomers/pharmacology
7.
Ter Arkh ; 89(7): 93-98, 2017.
Article in Russian | MEDLINE | ID: mdl-28766547

ABSTRACT

Breast implant-associated anaplastic large-cell lymphoma will be identified as a separate nosological entity in the 2017 adapted WHO classification due to differences in its clinical presentations, pathogenesis, and prognosis with those of nodal and cutaneous anaplastic large-cell lymphomas. The paper gives a review of the literature and describes the authors' own clinical case of common breast implant-associated anaplastic large-cell lymphoma involving breast tissue, axillary lymph nodes, anterior chest muscles, and bone marrow. The treatment policy chosen by the authors could achieve complete remission.


Subject(s)
Antineoplastic Combined Chemotherapy Protocols/administration & dosage , Breast Implantation , Breast Neoplasms , Lymph Nodes/pathology , Lymphoma, Large-Cell, Anaplastic , Adult , Axilla , Bone Marrow/pathology , Breast Implantation/adverse effects , Breast Implantation/methods , Breast Implants/adverse effects , Breast Neoplasms/etiology , Breast Neoplasms/pathology , Breast Neoplasms/therapy , Combined Modality Therapy/methods , Female , Humans , Lymphoma, Large-Cell, Anaplastic/etiology , Lymphoma, Large-Cell, Anaplastic/pathology , Lymphoma, Large-Cell, Anaplastic/therapy , Neoplasm Staging , Remission Induction , Silicone Elastomers/therapeutic use , Tomography, X-Ray Computed/methods , Ultrasonography, Mammary/methods
8.
J Prosthodont ; 26(7): 611-615, 2017 Oct.
Article in English | MEDLINE | ID: mdl-26845752

ABSTRACT

PURPOSE: Silicone-based elastomeric materials are commonly used to fabricate maxillofacial prostheses. The aim of this study was to evaluate the effect of different types of silica and nanosized titanium dioxide addition on the mechanical properties of two RTV silicone elastomers. MATERIALS AND METHODS: A-2000 and A-2006 silicone elastomers were used, and each was divided into four subgroups (n = 5). The first group was the control without additives. Other groups were titanium dioxide, fumed silica, and silaned silica. Each specimen was prepared in compliance with the manufacturer's instructions for the tensile strength, percent elongation, tear resistance, and the hardness tests according to ISO and ASTM standards. A factorial ANOVA with pairwise interaction indicated that the pattern for all four outcomes of the materials was different for A-2000 and A-2006 (p < 0.05). Therefore, the average outcome values for the materials within silicone elastomers were then analyzed by Tukey HSD. For the hardness test results, Kruskal-Wallis and Mann-Whitney U test methods were used. The level of statistical significance was p < 0.05. RESULTS: There was a statistically significant interaction (p < 0.05) between materials and silicone type for all four tests (tensile strength, tear, hardness, percent elongation). The hydrophobic silica group had significantly higher tensile strength than TiO2 for A-2000. The fumed hydrophilic silica group had significantly higher tensile strength than TiO2 for A-2006. Most of silica specimens had higher tensile strength when compared with the control and TiO2 groups for A-2000 and A-2006 silicones. The TiO2 group had the highest hardness value for A-2000 while the lowest hardness value for A-2006 (p < 0.05). There was no significant difference of tear strength among the type of additives (p > 0.05) for A-2000. The fumed silica and TiO2 groups had significantly higher tear strength than the control group for A-2006. The fumed silica and the hydrophobic silica groups had significantly higher percent elongation than the control group (p < 0.05) for A-2000. The TiO2 group had the lowest percent elongation for A-2006. CONCLUSIONS: Results in this in vitro study may clarify future studies about the effect of different additives on the physical and mechanical properties of maxillofacial elastomers. There is a great interest in the effect of a new-generation hydrophobic silica incorporation into A-2000 silicone as well as the effect of fumed hydrophilic silica incorporation into A-2006 silicone. Future research should be supported with more in vitro trials in different percentages of such additives used in this study.


Subject(s)
Maxillofacial Prosthesis , Nanoparticles/therapeutic use , Silicone Elastomers/therapeutic use , Titanium/therapeutic use , Dental Stress Analysis , Hardness , Humans , Prosthesis Design , Shear Strength , Tensile Strength
9.
J Craniofac Surg ; 27(8): 2149-2150, 2016 Nov.
Article in English | MEDLINE | ID: mdl-28005774

ABSTRACT

Tracheosephageal puncture is the one of the most favorable methods, and widely used by physicians for voice reconstruction after total laryngectomy. Intractable leakages from the tracheosephageal punctures are the most common complication, and management of these fistulas is still troublesome for the patients and physicians. Local surgical sutures, rotational flaps, injections are reported previously, but in this report the authors aimed to mention on a very simple method with silicone septal button. Insertion of a temporary silicone septal button may be well tolerated by patients and can help to manage this complication easily on exact indications. The authors discussed indications and long-term results of this method with different patients.


Subject(s)
Laryngeal Neoplasms/surgery , Punctures/adverse effects , Silicone Elastomers/therapeutic use , Tracheoesophageal Fistula/surgery , Wound Closure Techniques/instrumentation , Aged , Humans , Laryngectomy/adverse effects , Laryngectomy/methods , Larynx, Artificial , Male , Middle Aged , Punctures/methods , Surgical Flaps , Surgical Wound Dehiscence/etiology , Surgical Wound Dehiscence/surgery , Trachea/surgery , Tracheoesophageal Fistula/etiology
10.
Eye Contact Lens ; 41(2): 77-83, 2015 Mar.
Article in English | MEDLINE | ID: mdl-25230081

ABSTRACT

OBJECTIVE: To evaluate the relative pain and the relative amount of contact lens loss experienced using two different base curvatures (BCs) of the Acuvue Oasys bandage soft contact lens (BSCL) after photorefractive keratectomy (PRK). METHODS: One hundred forty patients undergoing PRK on either the Allegretto or the VISX laser at the Joint Warfighter Refractive Surgery Center in Lackland AFB, TX, were randomized to one of the two different BCs of the Acuvue Oasys BSCL: 8.4 or 8.8 mm. Patients were evaluated on postoperative days 1 and 4 during which they completed a survey rating absolute pain in each eye on a visual analog pain scale. Lens loss was recorded throughout the study. RESULTS: Patients treated on the Allegretto laser preferred the 8.4-mm BC lens, whereas comfort after treatment on the VISX depended on corneal shape. For VISX, patients with very flat corneas (steep K ≤42 preoperative or ≤38 postoperatively) preferred an 8.8-mm BC lens while patients with very steep corneas (steep K >45 preoperative or >42 postoperative) preferred an 8.4-mm BC lens, though these results were largely not statistically significant. Patients who lost their lenses prematurely tended to be those whose corneal curvature did not match their contact lens BC. CONCLUSIONS: Individuals treated with the Allegretto laser or individuals with more prolate corneas should likely be fit with an 8.4-mm BC Acuvue Oasys BSCL while individuals with more oblate corneas should likely be fit with an 8.8-mm BC lens to minimize postoperative pain and premature BSCL loss.


Subject(s)
Bandages, Hydrocolloid , Contact Lenses, Hydrophilic , Eye Pain/therapy , Photorefractive Keratectomy/adverse effects , Adult , Female , Humans , Hydrogels/therapeutic use , Male , Patient Satisfaction , Regression Analysis , Silicone Elastomers/therapeutic use , Young Adult
11.
J Med Microbiol ; 64(Pt 3): 199-208, 2015 Mar.
Article in English | MEDLINE | ID: mdl-25106862

ABSTRACT

Laryngopharyngeal malignancy is treated with radiotherapy and/or surgery. When total laryngectomy is required, major laryngeal functions (phonation, airway control, swallowing and coughing) are affected. The insertion of a silicone rubber voice prosthesis in a surgically created tracheoesophageal puncture is the most effective method for voice rehabilitation. Silicone, as is the case with other synthetic materials such as polymethylmethacrylate, polyurethane, polyvinyl chloride, polypropylene and polystyrene, has the propensity to become rapidly colonized by micro-organisms (mainly Candida albicans) forming a biofilm, which leads to the failure of the devices. Silicone is used within voice prosthetic devices because of its flexible properties, which are essential for valve function. Valve failure, as well as compromising speech, may result in aspiration pneumonia, and repeated valve replacement may lead to either tract stenosis or insufficiency. Prevention and control of biofilm formation are therefore crucial for the lifespan of the prosthesis and promotion of tracheoesophageal tissue and lung health. To date, the mechanisms of biofilm formation on voice prostheses are not fully understood. Further studies are therefore required to identify factors influencing Candida biofilm formation. This review describes the factors known to influence biofilm formation on voice prostheses and current strategies employed to prolong their life by interfering with microbial colonization.


Subject(s)
Biofilms/growth & development , Candida/growth & development , Candidiasis/microbiology , Larynx, Artificial/microbiology , Silicone Elastomers/therapeutic use , Candidiasis/prevention & control , Humans , Laryngectomy
12.
Einstein (Sao Paulo) ; 12(2): 186-90, 2014 Apr.
Article in English, Portuguese | MEDLINE | ID: mdl-25003924

ABSTRACT

OBJECTIVE: To describe a new surgical technique to treat pectus excavatum utilizing low hardness solid silicone block that can be carved during the intraoperative period promoting a better aesthetic result. METHODS: Between May 1994 and February 2013, 34 male patients presenting pectus excavatum were submitted to surgical repair with the use of low hardness solid silicone block, 10 to 30 Shore A. A block-shaped parallelepiped was used with height and base size coinciding with those of the bone defect. The block was carved intraoperatively according to the shape of the dissected space. The patients were followed for a minimum of 120 days postoperatively. The results and the complications were recorded. RESULTS: From the 34 patients operated on, 28 were primary surgeries and 6 were secondary treatment, using other surgical techniques, bone or implant procedures. Postoperative complications included two case of hematomas and eight of seromas. It was necessary to remove the implant in one patient due to pain, and review surgery was performed in another to check prothesis dimensions. Two patients were submitted to fat grafting to improve the chest wall contour. The result was considered satisfactory in 33 patients. CONCLUSION: The procedure proved to be fast and effective. The results of carved silicone block were more effective for allowing a more refined contour as compared to custom made implants.


Subject(s)
Funnel Chest/surgery , Plastic Surgery Procedures/methods , Prostheses and Implants , Silicone Elastomers/therapeutic use , Adolescent , Adult , Humans , Male , Middle Aged , Prosthesis Design , Retrospective Studies , Young Adult
13.
Ann Plast Surg ; 72(6): S198-201, 2014.
Article in English | MEDLINE | ID: mdl-24835874

ABSTRACT

INTRODUCTION: Hypertrophic scars (HTS) are a source of morbidity for burn survivors and can present with a range of lifestyle-limiting problems. These include pruritus, pain, burning, stiffness, and contractures. Many solutions have been developed, but few have been studied in the form of a prospective, randomized control trial (RCT). Given the importance these RCTs carry in shaping the treatment of burn patients, we sought to systematically and critically review this portion of the burn literature. METHODS: PubMed was used to perform 2 separate searches with limits that included Humans, English, and Randomized Controlled Trial. A keyword search using "hypertrophic," "Scar," "burn," and "treatment" was cross-referenced with a MeSH subject-heading search using "Cicatrix, Hypertrophic" AND "Burn." Studies were then reviewed and excluded if they did not address management of burn HTS in the non-acute setting. RESULTS: Two literature searches resulted in a total of 32 articles. Twelve articles were excluded because they were not relevant to the topic (n = 10) or could not be obtained (n = 2). The remaining 20 articles contained 882 patients treated for hypertrophic scars. Breakdown based on topics included laser therapy (58 patients, 2 articles), silicone gel (204 patients, 7 articles), compression garment (236 patients, 4 articles), silicone + pressure (226 patients, 3 articles), topical emollients (58 patients, 2 articles), systemic therapy (62 patients, 1 article), intralesional therapy (18 patients, 1 article), and surgical treatment (20 patients, 1 article). While some articles had favorable conclusions (laser, emollients, surgical, and intralesional therapy) or unfavorable conclusions (systemic therapy), there were conflicting results on silicone and/or compression. CONCLUSIONS: Despite hypertrophic scars being a common occurrence in burn survivors, both the number of studies and consensus for treatment are limited. Efforts to perform larger, adequately powered RCTs are needed, specifically in the areas of silicone, compression garments, and combination therapy.


Subject(s)
Burns/complications , Cicatrix, Hypertrophic/therapy , Cicatrix, Hypertrophic/etiology , Cicatrix, Hypertrophic/surgery , Humans , Randomized Controlled Trials as Topic , Silicone Elastomers/therapeutic use , Treatment Outcome
14.
Einstein (Säo Paulo) ; 12(2): 186-190, Apr-Jun/2014. graf
Article in English | LILACS | ID: lil-713015

ABSTRACT

Objective To describe a new surgical technique to treat pectus excavatum utilizing low hardness solid silicone block that can be carved during the intraoperative period promoting a better aesthetic result. Methods Between May 1994 and February 2013, 34 male patients presenting pectus excavatum were submitted to surgical repair with the use of low hardness solid silicone block, 10 to 30 Shore A. A block-shaped parallelepiped was used with height and base size coinciding with those of the bone defect. The block was carved intraoperatively according to the shape of the dissected space. The patients were followed for a minimum of 120 days postoperatively. The results and the complications were recorded. Results From the 34 patients operated on, 28 were primary surgeries and 6 were secondary treatment, using other surgical techniques, bone or implant procedures. Postoperative complications included two case of hematomas and eight of seromas. It was necessary to remove the implant in one patient due to pain, and review surgery was performed in another to check prothesis dimensions. Two patients were submitted to fat grafting to improve the chest wall contour. The result was considered satisfactory in 33 patients. Conclusion The procedure proved to be fast and effective. The results of carved silicone block were more effective for allowing a more refined contour as compared to custom made implants. .


Objetivo Descrever a técnica para reparação de pectus excavatum com o uso de bloco de silicone sólido de baixa dureza, que possibilita a adequação de suas dimensões no intraoperatório para melhor resultado estético. Métodos Entre maio de 1994 e fevereiro de 2013, pacientes do gênero masculino, portadores de pectus excavatum, foram submetidos à correção cirúrgica com bloco de silicone sólido de baixa dureza, de 10 a 30 Shore A, pré-fabricado em forma de paralelepípedo, com as dimensões da altura e da base coincidentes com as da falha óssea. Durante o ato cirúrgico, esse bloco foi esculpido até adequar-se ao formato do espaço dissecado. Os pacientes foram acompanhados por um mínimo de 120 dias de pós-operatório. Resultados Trinta e quatro pacientes foram operados. Destes, 28 foram de tratamento primário e 6 secundário a outras técnicas cirúrgicas, ósseas ou de uso de implantes. As complicações foram dois casos de hematoma e oito de seroma. Foi necessária a retirada do implante em um dos casos devido à dor. Em outro caso, foi a realizada revisão cirúrgica das dimensões da prótese. Dois pacientes foram submetidos a enxerto de gordura, para melhorar o contorno da parede torácica. Não ocorreu nenhum caso de infecção. O resultado foi considerado satisfatório em 33 pacientes. Conclusão O procedimento mostrou-se rápido e efetivo. Os resultados dos contornos obtidos foram considerados mais efetivos quando comparados aos obtidos com a utilização de próteses pré-moldadas. .


Subject(s)
Adolescent , Adult , Humans , Male , Middle Aged , Young Adult , Funnel Chest/surgery , Prostheses and Implants , Plastic Surgery Procedures/methods , Silicone Elastomers/therapeutic use , Prosthesis Design , Retrospective Studies
15.
Braz. j. oral sci ; 13(2): 158-162, Apr-Jun/2014. tab, graf
Article in English | LILACS | ID: lil-715604

ABSTRACT

AIM : To evaluate the influence of finishing and polishing techniques on the surface roughness of two composite resins (CRs) subjected to bleaching procedure. METHODS : Forty-eight CR specimens were divided into six groups (n=8). For G1 to G3, a microhybrid CR (Opallis; FGM) was used, and G4 to G6, received a nanohybrid CR (Brilliant NewLine; Coltène/Whaledent). All specimens were subjected to bleaching procedure with 35% hydrogen peroxide (two 45-min applications, with a 5-day interval). The surface roughness of all specimens was evaluated before and after the bleaching and/or finishing/polishing (Ra parameter) by a roughness meter. After bleaching, the groups were subjected to finishing and polishing procedures: G2 and G5 - felt discs + diamond pastes; and G3 and G6 - silicon rubber tips. The control groups (G1 and G4) had no finishing or polishing treatment after bleaching. Data were analyzed by ANOVA and Tukey's post-test, and t test for paired samples (a=0.05). RESULTS : bleaching treatment increased Ra values for the nanohybrid CR specimens, but both finishing/polishing techniques were able to reduce these values; for the microhybrid specimens, only finishing/polishing with silicon rubber tips decreased the roughness values. CONCLUSIONS : For both microhybrid and nanohybrid CRs, the silicon rubber tips were effective to reduce the surface roughness after bleaching procedure...


Subject(s)
Anti-Infective Agents, Local/therapeutic use , Composite Resins , Tooth Bleaching/adverse effects , Silicone Elastomers/therapeutic use , Hydrogen Peroxide/therapeutic use , Dental Polishing/adverse effects
16.
Neuroradiology ; 55(1): 65-70, 2013 Jan.
Article in English | MEDLINE | ID: mdl-22847650

ABSTRACT

INTRODUCTION: Previous studies have noted formation of saccular aneurysms along the distal basilar artery/P1 segments after carotid ligation in rabbits. In this prospective study we employed MICROFIL®, a polymer, which was used to fill the entire arterial tree, to examine the incidence of microaneurysm formation following right common carotid artery (RCCA) ligation in rabbits. METHODS: RCCA ligation was performed in 18 New Zealand White rabbits for 0 day (n = 2), 3 weeks (n = 6), or 16 weeks (n = 10). Three control rabbits without carotid surgery were sacrificed at 4 weeks. At the time of sacrifice, MICROFIL® MV-122 yellow was injected through left CCA to fill cerebral vasculature. After gross photographs were taken, specimens were embedded, sectioned, and stained for histopathological evaluation. Tissue and sections were carefully evaluated for microaneurysm formation, defined as a localized dilatation of the vessel wall, associated with fragmentation or complete loss of the internal elastic lamina (IEL), and/or medial degeneration. RESULTS: Gross examination with MICROFIL® opacification demonstrated no evidence of saccular aneurysm formation, but prominent perforating vessels were present in all 19 cases at, or adjacent to, the basilar terminus. Branches noted upon gross examination corresponded histologically to small, saccular contour defects, which demonstrated apparent loss of the IEL and apparent medial thinning. These observations, however, were a consequence of sectioning through the bases of perforating arteries, which simulated microaneurysm formation. CONCLUSIONS: Unilateral carotid ligation does not induce microaneurysm formation at the basilar terminus in rabbits. Prominent perforating arteries as well as tissue injury from the processing may simulate "aneurysms" histologically.


Subject(s)
Aneurysm/prevention & control , Carotid Artery Diseases/prevention & control , Embolization, Therapeutic/methods , Silicone Elastomers/therapeutic use , Aneurysm/diagnosis , Animals , Carotid Artery Diseases/diagnosis , Hemostatics/therapeutic use , Ligation , Rabbits , Treatment Outcome
17.
Br J Oral Maxillofac Surg ; 51(4): 319-25, 2013 Jun.
Article in English | MEDLINE | ID: mdl-22818045

ABSTRACT

The use of space maintenance in mandibular defects as an interim measure before definitive osseous reconstruction may prevent problems associated with delayed reconstruction including increased technical difficulty, contracture of soft tissues that limits the volume of the final reconstruction, and the potential for iatrogenic injury to adjacent anatomical structures. The use of a condyle/ramus spacer made of medical grade, ultrahigh-molecular-weight polyethylene, and a flexible body spacer made of high quality, inert, non-toxic medical and food grade silicone rubber, was tested in 38 patients with mandibular defects after the resection of benign but locally aggressive disease, advanced osteomyelitis, and injuries. The spacer was retained for a maximum of 8 weeks, and was then removed through an extraoral approach before definitive reconstruction with a particulate corticocancellous bone graft. One of the 38 patients failed to attend for follow up and returned 7 months later with severe, generalised sepsis that required removal of the spacer and exclusion from the study. Of the remaining 37 patients, 32 healed uneventfully, 1 required removal of the spacer 2 weeks after implantation for intraoral wound dehiscence, and 4 had mild to moderate disturbances of wound healing that required either minor revision or local wound care until removal at the time of reconstruction. The use of a spacer promotes wound healing and simplifies and expedites secondary reconstruction of mandibular defects.


Subject(s)
Mandibular Prosthesis , Mandibular Reconstruction/instrumentation , Plastic Surgery Procedures/methods , Adolescent , Adult , Aged , Bone Transplantation/methods , Child , Computer-Aided Design , Female , Follow-Up Studies , Humans , Imaging, Three-Dimensional/methods , Male , Mandible/surgery , Mandibular Condyle/surgery , Mandibular Diseases/surgery , Mandibular Injuries/surgery , Mandibular Neoplasms/surgery , Mandibular Prosthesis Implantation/methods , Mandibular Reconstruction/methods , Middle Aged , Osteomyelitis/surgery , Patient Care Planning , Polyethylenes/therapeutic use , Plastic Surgery Procedures/instrumentation , Silicone Elastomers/therapeutic use , Surgical Wound Dehiscence/etiology , Surgical Wound Infection/etiology , User-Computer Interface , Young Adult
18.
Facial Plast Surg ; 28(5): 513-7, 2012 Oct.
Article in English | MEDLINE | ID: mdl-23027218

ABSTRACT

Minimizing scar size, width, and contour of elevation is a common goal for the facial plastic surgeon. Various standard techniques are employed to reduce tension and enhance the rapid and uneventful healing of incisions. In some cases, these routine measures are not judged to be adequate, and additional intraoperative and postsurgical measures are employed to control the body's innate healing processes. Mitomycin C and self-drying silicone gel have been particularity useful in our practice.


Subject(s)
Antibiotics, Antineoplastic/therapeutic use , Cicatrix, Hypertrophic/therapy , Keloid/therapy , Mitomycin/therapeutic use , Plastic Surgery Procedures/methods , Wound Healing/drug effects , Adolescent , Adult , Child , Cicatrix, Hypertrophic/etiology , Cicatrix, Hypertrophic/pathology , Cicatrix, Hypertrophic/physiopathology , Dermatologic Surgical Procedures/adverse effects , Female , Humans , Keloid/etiology , Keloid/pathology , Keloid/physiopathology , Male , Occlusive Dressings , Silicone Elastomers/therapeutic use , Young Adult
19.
Ophthalmic Plast Reconstr Surg ; 27(5): e131-2, 2011.
Article in English | MEDLINE | ID: mdl-21283031

ABSTRACT

A 37-year-old man presented with symptoms of air and mucus reflux from the right medial canthus on blowing his nose. Examination showed crepitus in the region overlying the right lacrimal sac, and he was able to produce bubbles in his conjunctival lake on instillation of topical 2% fluorescein. Dacryoscintigraphy showed symmetrical slow passage of tracer from the lacrimal sac in the nasolacrimal duct indicating delay at the postsac level. Dacryocystography showed that the right lacrimal system contained round filling defects, suggesting the presence of soft tissue tumors. However, a CT scan showed an enlarged right lacrimal fossa with air in the nasolacrimal duct and no evidence of a mass. Following lower punctal plug occlusive canaliculoplasty on the right, using a preloaded silicone plug, the patient noted an immediate resolution of reflux symptoms.


Subject(s)
Emphysema/therapy , Lacrimal Apparatus Diseases/therapy , Prostheses and Implants , Adult , Humans , Male , Silicone Elastomers/therapeutic use , Therapeutic Occlusion/methods , Tomography, X-Ray Computed
20.
Strabismus ; 19(1): 12-6, 2011 Mar.
Article in English | MEDLINE | ID: mdl-21314337

ABSTRACT

Fibrosis of the extraocular muscles can be an acquired or congenital disorder (CFEOM). The congenital disorder(1) is a complex strabismus with congenital restrictive ophthalmoplegia with or without ptosis. The surgery is challenging because the eye muscles are replaced by fibrous tissue or fibrous bands and in most cases the results are not satisfactory. We present the first case report of unilateral CFEOM with palpebral adherence and hypotropia, which was managed with our technique of a silicon plate implant on the orbital floor. The purpose of the implantation of the silicon plate in the orbital floor is to improve the hypotropia caused by CFEOM.


Subject(s)
Eyelid Diseases/surgery , Oculomotor Muscles/surgery , Ophthalmoplegia/surgery , Orbit/surgery , Silicone Elastomers/therapeutic use , Strabismus/surgery , Child , Eyelid Diseases/congenital , Eyelid Diseases/diagnosis , Fibrosis/congenital , Functional Laterality , Humans , Magnetic Resonance Imaging , Male , Oculomotor Muscles/diagnostic imaging , Oculomotor Muscles/pathology , Ophthalmologic Surgical Procedures , Ophthalmoplegia/congenital , Ophthalmoplegia/diagnosis , Strabismus/congenital , Strabismus/diagnosis , Tomography, X-Ray Computed
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