Estudio descriptivo y analítico del "Formulario cirujíco para uso del Hospital del Militar de Mahón" / Surgical Formulary for use at the Military Hospital of Mahon

El "Formulario cirujíco para el uso del Hospital Miliar de Mahón" fue redactado por el director del hospital y cirujano mayor el Dr. Manuel Rodríguez Caramazana el 25 de marzo de 1808. Este artículo recoge el estudio descriptivo y analítico realizado en la edición facsímil del formulario publicada en 2014 por la Fundación Uriach en colaboración con la Fundación Hospital Illa del Rei. El Hospital de la Isleta o Real Hospital del Ejército y la Marina fue considerado el más relevante entre los hospitales militares de la península ibérica, por su situación geográfica y por las aplicaciones terapéuticas, quirúrgicas y medicamentosas realizadas. El estudio contextualiza el texto original y describe los preparados farmacéuticos utilizados en la asistencia a los heridos de este Hospital de Menorca durante la Guerra de la Independencia Española y que, un siglo más tarde, todavía fueron utilizados en hospitales europeos de renombre como el de París

The Surgery Formulary for the use at the Military Hospital of Mahon was critten by the hostpial director and surgeon-major Dr. Manuel Rodríguez Caramazana on 25th March 1808. This article includes the descriptive and analytical study carried out in the facsimile edition of the formulary published in 2014 by the Uriach Foundation in collaboration with the Hospital Illa del Rei Foundation. The Isleta Hospital or Royal Army and Navy Hospital was considered the most relevant among the military hospitals on the Iberian Peninsula, for its geographical location and the therapeutic, surgical and clinical treatments aplied. The study contextualizes the original text and describes the pharmaceutical preparations used in the care of the wounded of this Menorca Hospital during the Sapnish War of Independence and that, a century later, were still used in renowned European hospitals such as that in Paris

[Ophthalmia neonatorum of the newborn and its treatments in Canadian medical publications: 1872-1985]. / L'ophtalmie du nouveau-né et ses traitements á la lecture des publications médicales canadiennes: 1872-1985.

In the 19th century the occurrence of ophthalmia neonatorum had reached alarming rates in the maternity wards not only of Europe but also across Canada. The impact of this blinding ocular infection on Canadian medicine from 1872 to 1985 is examined through a review of 80 medical journals, books, and lay press articles of that period. The prophylactic and therapeutic use of 2% silver nitrate introduced by Credé in 1880 to prevent neonatal blindness is reviewed. The signs, symptoms, and corneal complications of this disease as well as the multiple ocular drugs used during this era will be presented. The judicial consequences on midwives and obstetricians will be discussed. The subsequent use of colloidal silver based agents such as collargol, protargol and argyrol followed by the introduction of sulfonamides and finally the routine use of prophylactic topical antibiotics will be reviewed.

A historical review of the use of silver in the treatment of burns. II. Renewed interest for silver.

In 1965, Moyer revived interest in silver nitrate solution. He concluded on the basis on in vitro and in vivo studies that a 0.5% solution represented the lowest concentration at which antibacterial action (against Staphylococcus aureus, haemolytic streptococci and generally against Pseudomonas aeruginosa and E. coli) was obtained. Mafenide acetate was introduced a short time after the reintroduction of silver nitrate, followed a few years later by silver sulphadiazine. Thus, in a short period of time three medicaments appeared on the market which represented a radical change in the topical treatment of burns. The action of silver sulphadiazine has been intensively studied. Since silver sulphadiazine does not offer sufficient protection to prevent or retard the growth of gram-negative bacteria in patients with burns covering more than 50% of body surface, Monafo introduced the combined preparation silver sulphadiazine and cerium nitrate. Although various attempts have been made to develop more effective silver compounds, so far silver sulphadiazine still remains the most widely used substance of this type.