1.
Pharm Weekbl Sci
; 5(6): 298-301, 1983 Dec 16.
Article
in English
| MEDLINE
| ID: mdl-6664822
ABSTRACT
In this study the preparation of five hydrophilic derivatives of sulfadiazine is reported. The common structural element in the compounds is the 2-sulfonamidopyrimidine moiety. Three of these compounds are suitable for the preparation of a photostable I: I silver compound. These silver compounds are five to ten times more water soluble than silver sulfadiazine. The IR, 1H- and 13C-NMR data point to a similar co-ordination of silver in these compounds as with silver sulfadiazine. The microbiological activity of these silver compounds against St. aureus is slightly lower.