ABSTRACT
We report a case of a 66-year-old Taiwanese female patient with situs ambiguus diagnosed of pancreatic head cancer. She was treated with gemcitabine and erlotinib and remained in stable disease on follow-up imaging studies. Situs ambiguus is a rare disease and reports of such patients with cancer have rarely been reported in the literature. Our case illustrates that standard chemotherapy in this group of patients may be undergone with promising results.
Subject(s)
Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Pancreatic Neoplasms/drug therapy , Situs Inversus/drug therapy , Aged , Deoxycytidine/administration & dosage , Deoxycytidine/analogs & derivatives , Erlotinib Hydrochloride , Female , Humans , Pancreatic Neoplasms/complications , Quinazolines/administration & dosage , Situs Inversus/complications , Treatment Outcome , GemcitabineABSTRACT
Situs inversus (SI), is left to right inversion of internal organs. It may remain unrecognized until discovery during emergency surgery or investigation of symptoms. There are three reports of lung cancer with SI in Medline. However search in PubMed by 15 December 2008, there isn't any report of superior vena cava syndrome (SVCS) with any benign or malignant disease in patients with SI. We present the case of a 59 year old man with small cell carcinoma in left main bronchus presented with SVCS. Chest radiography and contrast enhanced CT scan confirmed SI with compression left side located superior vena cava with left lung small cell carcinoma. To our knowledge, here, we present the first case of SVCS with SI.