ABSTRACT
AIM: To study the effects of nooclerin (deanol aceglumate) on the structure of sleep disturbances in children with tension-type headache (TTH). MATERIAL AND METHODS: A blind randomized placebo-controlled study of the efficacy of nooclerin (deanol aceglumate), prescribed for 2 months to prevent TTH, was carried out. The study included 60 patients (30 boys and 30 girls), aged 9-16 years, with TTH. Patients were randomized into the nooclerin group (n=30) and the placebo group (n=30). Sleep disturbances were assessed before and after treatment with the Sleep Disturbance Scale for Children (SDSC). RESULTS: There was a significant positive dynamics (reduced total score on SDSC (p<0.001) and a significant decrease in the scores on scales 'Disorders of initiating and maintaining sleep', 'Disorders of excessive somnolence' (p<0.001), 'Sleep wake transition disorders' (p<0.01)) in the nooclerin group. No significant positive changes were detected in the placebo group. CONCLUSION: An anxiolytic action of nooclerin was confirmed. Further studies of the drug in child neurology and psychiatry using larger groups of patients are needed.
Subject(s)
Anti-Anxiety Agents , Deanol , Glutamates , Sleep Wake Disorders , Tension-Type Headache , Adolescent , Anti-Anxiety Agents/therapeutic use , Child , Deanol/therapeutic use , Female , Glutamates/therapeutic use , Humans , Male , Sleep , Sleep Wake Disorders/congenital , Sleep Wake Disorders/drug therapy , Tension-Type Headache/complications , Tension-Type Headache/drug therapyABSTRACT
The importance of sleep in the development is only now beginning to be understood: sleep and established sleep cycles have an important role in the normal neurosensory and cortex development. The biological basis of sleep organization has been highlighted by several studies however environmental differences can affect the sleep patterns in preterm infants in the NICU. Sleep disorders are related to several physiological conditions but it is important to know the relationship between sleep organization and neurocognitive and socio-emotional outcomes. From the recent literature it is possible to find out potentially better practices that preserve and promote infant sleep in the NICU.
Subject(s)
Infant, Premature/physiology , Sleep Wake Disorders/congenital , Sleep Wake Disorders/prevention & control , Sleep/physiology , Humans , Infant, Newborn , Intensive Care Units, Neonatal/standards , Neonatology/methods , Neonatology/standards , Sleep Wake Disorders/physiopathologyABSTRACT
Sleep is a very important element for the development of a premature newborn, because it helps in creating good clinical condition, good weight gain, mastering full oral feeding and improving parent-infant relationship as well. Moreover, the development of a correct sleeping-awaking pattern is a key factor for the development of the brain. To protect sleep is important to modify the environment, for example, reducing noise levels, creating period of semi darkness and protecting infant face from direct light. To obtain this, individualized care, based on infant behavioural cues, becomes fundamental, requiring a change in daily assistance that should become more relationship-oriented. It is also fundamental to foster the presence of parents because it helps the baby to feel more protected and allows him to relax.
Subject(s)
Infant Care/methods , Intensive Care Units, Neonatal , Sleep Wake Disorders/prevention & control , Sleep/physiology , Humans , Infant Care/organization & administration , Infant, Newborn , Infant, Premature/physiology , Intensive Care Units, Neonatal/organization & administration , Parents , Sleep Wake Disorders/congenitalABSTRACT
Este trabajo orienta a que los hàbitos de sueño de la poblaciòn estudiada,no son exactamente los descritos como ideales en la literatura.Hay muchas soluciones que se pueden iniciar.La educaciòn es la clave..
