ABSTRACT
Introduction: The purpose of this paper is to study the type, the clinical presentation, and the best diagnostic methods for pleural solitary fibrous tumors (PSFTs), as well as to evaluate which is the most appropriate treatment, especially as PSFTs represent a rare occurrence in the thoracic pathology. Material and Method: A retrospective study was conducted on a group of 45 patients submitted to surgery between January 2015 and December 2019. In most cases, the diagnosis was established through imaging studies-thoracic computed tomography (CT) scan with or without contrast-but also using magnetic resonance imaging (MRI) or positron emission tomography (PET) scans when data from CT scans were scarce. All patients were submitted to surgery with curative intent. Results: Most patients included in this study were asymptomatic, with this pathology being more common in patients over 60 years of age, and more common in women. The occurrence of malignant PSFT in our study was 17.77% (8 cases). All cases were submitted to surgery with curative intent, with a single case developing further recurrence. In order to achieve complete resection en bloc resection of the tumor with the chest wall, resection was performed in two cases, while lower lobectomy, pneumectomy, and hemidiaphragm resection, respectively, were needed in each case. Postoperative mortality was null. Conclusion: Thoracic CT scan remains the most important imagistic investigation in diagnosing. MRI is superior to thoracic CT, especially in cases that involved the larger blood vessels within the thorax, spinal column, or diaphragm. Complete surgical resection is the gold standard in treatment of PSFT, and the prognosis in benign cases is very good.
Subject(s)
Solitary Fibrous Tumor, Pleural/diagnosis , Adult , Aged , Aged, 80 and over , Female , Humans , Magnetic Resonance Imaging , Male , Middle Aged , Neoplasm Staging , Retrospective Studies , Sex Distribution , Solitary Fibrous Tumor, Pleural/physiopathology , Solitary Fibrous Tumor, Pleural/surgery , Tomography, X-Ray ComputedABSTRACT
No disponible
Subject(s)
Humans , Male , Female , Solitary Fibrous Tumor, Pleural/diagnosis , Solitary Fibrous Tumor, Pleural/physiopathology , Lipoma/chemically induced , Lipoma/diagnosis , Facial Neoplasms/chemically induced , Solitary Fibrous Tumor, Pleural/chemically induced , Solitary Fibrous Tumor, Pleural/complications , Lipoma/pathology , Lipoma/psychology , Facial Neoplasms/psychologyABSTRACT
No disponible
Subject(s)
Humans , Male , Aged , Solitary Fibrous Tumor, Pleural/complications , Solitary Fibrous Tumor, Pleural/surgery , Solitary Fibrous Tumor, Pleural , Incidental Findings , Tomography, Emission-Computed/instrumentation , Tomography, Emission-Computed/methods , Tomography, Emission-Computed , Laparotomy/methods , Laparotomy , Solitary Fibrous Tumor, Pleural/physiopathology , Retroperitoneal Fibrosis/complications , Retroperitoneal Fibrosis/surgery , Retroperitoneal Neoplasms/surgery , Retroperitoneal Neoplasms , Retroperitoneal Space/pathology , Retroperitoneal Space/surgerySubject(s)
Pleura/pathology , Pneumonectomy/methods , Solitary Fibrous Tumor, Pleural , Aged , Arthralgia/etiology , Arthralgia/physiopathology , Disease Progression , Erythema/etiology , Erythema/physiopathology , Fatigue/etiology , Fatigue/physiopathology , Fever/etiology , Fever/physiopathology , Humans , Male , Osteoarthropathy, Secondary Hypertrophic/etiology , Osteoarthropathy, Secondary Hypertrophic/physiopathology , Positron-Emission Tomography/methods , Recovery of Function , Solitary Fibrous Tumor, Pleural/complications , Solitary Fibrous Tumor, Pleural/diagnosis , Solitary Fibrous Tumor, Pleural/physiopathology , Solitary Fibrous Tumor, Pleural/surgery , Tomography, X-Ray Computed/methods , Treatment OutcomeABSTRACT
Solitary fibrous tumor (SFT) of the pleura is an uncommon neoplasm with non-specific symptoms and non-pathognomonical radiological findings. Surgery allows establishment of a definitive diagnosis as well as a cure of the disease. The role of radiotherapy or chemotherapy in the management of the disease is unclear because of the rarity of the disease and the successful results of the surgical treatment. Long-term clinical follow-up may be useful for the patients with SFT because of the potential adverse biological behavior of this tumor, which may lead to repeated recurrences and/or malignant transformation. We reported a 66-year-old woman with recurrence of SFT in the right lung, which had significant response to external thoracic radiotherapy.
Subject(s)
Neoplasm Recurrence, Local/radiotherapy , Solitary Fibrous Tumor, Pleural/radiotherapy , Aged , Dyspnea/etiology , Female , Humans , Immunohistochemistry , Neoplasm Recurrence, Local/pathology , Neoplasm Recurrence, Local/physiopathology , Palliative Care , Solitary Fibrous Tumor, Pleural/pathology , Solitary Fibrous Tumor, Pleural/physiopathology , Tomography, X-Ray Computed , Treatment OutcomeABSTRACT
Solitary fibrous pleural tumors are rare masses of mesenchymal origin that may be mistaken for mesothelioma. A positive staining of vimentin, negative staining of cytoplasmic keratin, and expression of the CD34 antigen can confirm the presence of a solitary fibrous pleural tumor. Although most tumors of this type are benign, they possess a malignant potential and thus should be excised. We report a case of a 63-year-old man who had an inconclusive biopsy of a lung lesion 15 years ago. Further testing after excision revealed a solitary fibrous pleural tumor. A brief discussion of the clinical presentation and incidence of these tumors is included.
