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Article in Russian | MEDLINE | ID: mdl-3414248

ABSTRACT

Experimental and clinical studies of the autoimmune component of the reactive inflammatory process in tissues of the vertebral canal, caused by the presence of elements of an intervertebral disk, have allowed the authors to investigate the immune reaction of a delayed type and prove that it is immunocomplex in nature and manifests 3 weeks after the elements of the intervertebral disk have found their way into the immunocompetent system. The presence of immunoglobulins around the vessels and in the spinal membranes sheds some light on the autoimmune origin of cicatricial changes in these anatomical structures.


Subject(s)
Autoimmune Diseases/immunology , Lumbar Vertebrae , Nerve Compression Syndromes/immunology , Osteochondritis/immunology , Spinal Nerve Roots , Animals , Autoimmune Diseases/complications , Autoimmune Diseases/pathology , Biopsy , Humans , Immunoglobulins/analysis , Intervertebral Disc/immunology , Intervertebral Disc/pathology , Nerve Compression Syndromes/etiology , Nerve Compression Syndromes/pathology , Osteochondritis/complications , Osteochondritis/pathology , Rabbits , Spinal Canal/immunology , Spinal Canal/pathology , Time Factors
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