ABSTRACT
Splenic infarction caused by malaria can be fatal, but its incidence and clinical presentation are not well-known. Thus, we investigated the prevalence and characteristics of splenic complications in patients with vivax malaria from 2005 to 2017 in a university hospital. Among 273 patients who were diagnosed with Plasmodium vivax infection by blood smear, 92 underwent abdominal computed tomography or ultrasonography. Twelve patients had splenic infarction. All patients with splenic infarction recovered after treatment with antimalarial drugs, without surgery and intervention. Although anemia and prolonged fever may be risk factors for splenic infarction, the incidence of these events was insufficient for a detailed analysis.
Subject(s)
Antimalarials/therapeutic use , Malaria, Vivax/epidemiology , Plasmodium vivax/isolation & purification , Splenic Infarction/epidemiology , Abdomen/diagnostic imaging , Adult , Female , Hospitals, University , Humans , Incidence , Malaria, Vivax/diagnostic imaging , Malaria, Vivax/drug therapy , Malaria, Vivax/parasitology , Male , Middle Aged , Republic of Korea/epidemiology , Spleen/diagnostic imaging , Splenic Infarction/diagnostic imaging , Splenic Infarction/drug therapy , Splenic Infarction/parasitology , Tomography, X-Ray Computed , Ultrasonography , Young AdultABSTRACT
In tropical countries like India, malaria has been one of the most common parasitic illnesses leading to frequent hospitalization and causing major economic burden among the masses. Although Plasmodium vivax infection is considered to be benign, in contrast to Plasmodium falciparum infection which is notorious for its severe splenic complications can occur frequently. Splenomegaly tends not to receive special attention, as it is not usually accompanied by any symptoms and can be gradually resolved via standard antimalarial therapy. Splenic infarction, although rarely attributable to malaria in an endemic region with high parasitemia, can be a rare presentation of this disease entity.
Subject(s)
Malaria, Vivax/parasitology , Plasmodium vivax/isolation & purification , Splenic Infarction/parasitology , Abdomen/diagnostic imaging , Abdomen/parasitology , Adolescent , Female , Humans , Malaria, Vivax/diagnostic imaging , Splenic Infarction/diagnostic imaging , UltrasonographyABSTRACT
We present three cases of unusual and complicated malaria caused by Plasmodium vivax. Parenteral artemisinin derivatives or quinine should be used, irrespective of chloroquine sensitivity, for treatment of severe malaria.
Subject(s)
Antimalarials/therapeutic use , Malaria, Vivax/complications , Plasmodium vivax/pathogenicity , Respiratory Distress Syndrome/etiology , Shock/etiology , Splenic Infarction/etiology , Adult , Animals , Antimalarials/pharmacology , Artemisinins/therapeutic use , Artesunate , Chloroquine/therapeutic use , Female , Humans , Malaria, Vivax/drug therapy , Malaria, Vivax/parasitology , Male , Middle Aged , Plasmodium vivax/drug effects , Plasmodium vivax/isolation & purification , Primaquine/therapeutic use , Respiratory Distress Syndrome/parasitology , Shock/drug therapy , Shock/parasitology , Splenic Infarction/drug therapy , Splenic Infarction/parasitology , Treatment OutcomeABSTRACT
We describe 2 patients with Babesia infection who presented with fever and multiple splenic infarcts. There were no other conditions present that could potentially be causes of splenic infarction. Although retinal infarction has been described rarely in patients with babesiosis, splenic infarction has not been reported previously in association with this infection in humans.
Subject(s)
Babesiosis/complications , Splenic Infarction/parasitology , Aged , Animals , Babesiosis/diagnosis , Babesiosis/diagnostic imaging , Babesiosis/parasitology , Female , Humans , Male , Middle Aged , RadiographyABSTRACT
Splenic infarction is a rare complication in malaria cases, and is caused primarily by Plasmodium falciparum. Recently in South Korea, only P. vivax has prevailed since 1993. Although the probability that symptomatic splenic infarction may occur in vivax malaria cases is considered relatively high, there have never been any case reports describing the occurrence of symptomatic splenic infarction in cases of vivax malaria. A 34-year-old man presented with fever that had persisted for 5 days. P. vivax infection was verified using a peripheral blood smear, and chloroquine was utilized to treat the fever successfully. Six days later, the patient developed pain in the left upper abdomen, which was diagnosed as splenic infarction by computed tomography.
Subject(s)
Malaria, Vivax/complications , Plasmodium vivax/isolation & purification , Splenic Infarction/parasitology , Adult , Animals , Humans , Malaria, Vivax/blood , Malaria, Vivax/drug therapy , Male , Primaquine/therapeutic use , Splenic Infarction/bloodABSTRACT
Splenic infarct during P. falciparum malaria is rare but well known. We report one case where ultrasonography and computed tomography suggested the diagnostic, showing respectively in splenic parenchyma a peripheral hypoechoic lesion and a low attenuation lesion. Diagnostic was confirmed by spontaneous regression during following days. We shall encounter more frequently than nowadays this rare entity due to expanding tourism and P. falciparum resistance.