Subject(s)
Granuloma/pathology , Granulomatosis, Orofacial/diagnosis , Intubation/adverse effects , Sialometaplasia, Necrotizing/pathology , Sublingual Gland Neoplasms/pathology , Tongue Neoplasms/etiology , Tongue/pathology , Adrenal Cortex Hormones/therapeutic use , Aged , Diagnosis, Differential , Female , Humans , Sialometaplasia, Necrotizing/drug therapy , Sialometaplasia, Necrotizing/etiology , Sublingual Gland Neoplasms/drug therapy , Sublingual Gland Neoplasms/etiology , Tongue Neoplasms/diagnosisABSTRACT
We described an extremely rare case of adenoid cystic carcinoma associated with salivary duct cyst in the sublingual gland of a 40-year-old Japanese woman. The tumor was growing from the cyst wall and almost occluded the cyst lumen. The epithelium lining the cyst lumen contained both keratin 19-positive cells and alpha-smooth muscle actin-positive cells, indicating the cyst being derived from the acinus/intercalated duct of the sublingual gland. Therefore, our case has presented for the first time a direct evidence that adenoid cystic carcinoma arises from acinus/intercalated duct.
Subject(s)
Carcinoma, Adenoid Cystic/etiology , Cysts/complications , Salivary Ducts , Sublingual Gland Neoplasms/etiology , Adult , Carcinoma, Adenoid Cystic/pathology , Cysts/pathology , Female , Humans , Salivary Ducts/pathology , Salivary Gland Diseases/complications , Salivary Gland Diseases/pathology , Sublingual Gland/pathology , Sublingual Gland Neoplasms/pathologyABSTRACT
Salivary gland lymphoma is associated with Sjögren's syndrome. A case of bilateral submandibular gland and sublingual gland lymphoma, arising in Sjögren's syndrome, is presented. A lymphoma involving more than one salivary gland may occur in Sjögren's syndrome, and there is an increased risk of developing an extrasalivary lymphoma.
